Scientist I, Target Biology (25104-R-670-TB)

WHO WE ARE

Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We seek a talented and experienced Scientist to work on-site based in our South San Francisco office. 

ArsenalBio’s mission and purpose are very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.

Driven by a collective of diverse experts across multi-scientific disciplines and clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.

This means you’ll have the opportunity to work with the best talent in the field of cell therapy and be part of ONE TEAM, which advances therapies for patients who need it most.

• Lead efforts to identify and characterize target antigens for oncology CAR T applications
• Identify and utilize in silico databases for target discovery, validation and risk assessment 
• Develop and optimize RNA- and protein-based assay and platforms to validate target antigen profiles
• Design and lead experimental approaches to evaluate the interplay between internal products and existing or emerging therapeutics
• Investigate the impact of internal CAR T cells on indication-specific tumors through innovative experimental strategies
• Coordinate cell line engineering activities to enable CAR T cell candidate screening development
• Stay up to date with relevant literature and apply key insights to target selection and indications of interest
• Manage and coordinate cross-functional workstreams across multiple projects, ensuring effective prioritization and strategic planning 
• Execute, analyze, and present  experimental findings in cross-functional settings, aligning with project timelines, goals, and long-term strategy
• Mentor and guide junior colleagues, providing subject matter expertise and professional development support

• PhD in cancer, molecular or cellular biology, or a related field with 0-2+ years of relevant research experience in industry or equivalent in academia; OR a Masters with 5+ years of relevant experience; OR a Bachelor's degree with 7+ years of relevant experience
• Demonstrated scientific contributions through publications and/or development of cell therapies
• Hands-on expertise in RNA and protein-based experimental approaches (e.g IHC, Western blot, ELISA, RT-qPCR, RNA-seq, multi-color flow cytometry)
• Experienced working in highly collaborative, cross-functional team settings
• Creative, adaptable, and goal-oriented with strong team-first mindset

• Deep expertise in cancer biology, with a strong understanding of the tumor microenvironment and interactions with immune cells
• Experience in cell therapy (e.g CAR T, bispecific antibody, etc.) 
• Proficiency in silico analyses of bulk and scRNA-seq datasets (e.g R, Python)
• Experience mentoring or managing research associates and junior scientists

BENEFITS AND PAY

ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge. 

Our people-first culture cultivates a deep respect for humanity, not only in those we serve but also in one another. We take pride in being part of a company that values and celebrates diversity—in experiences, ideas, and interests. We are empowered in an environment that embraces unity and inclusivity, fostering a sense of belonging and mutual respect.

We provide powerful tools to empower our employees to take charge of their career paths and reach their full potential. At ArsenalBio, we believe in investing in our employees' well-being—both professionally and personally—because our people are our most valuable asset. Our essential team members bring exceptional expertise in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software, and other fields to turn the possibilities of tomorrow into the realities of today.

We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

We are an equal opportunity employer and deeply value diversity within our company. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability.

The estimated base salary for the preferred primary location of the San Francisco Bay area ranges from $113,600 to $ 139,100. Salary ranges for other locations may vary.  Base pay offered may vary based on job-related knowledge, experience, education, and location. Beyond these considerations, we are committed to pay equity and consider the internal equity of our current employees when making any final offers.

To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias or to ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.