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Research Data Scientist II/Sr Research Data Scientist

JOB SUMMARY

We are seeking a skilled Senior Machine Learning Scientist to join our team at the Iambic Therapeutics. In this role, you will work to design, develop, train, benchmark, and deploy one out of two of our machine learning models. 

1.     NeuralPLexer is a protein-ligand structure prediction model based on equivariant diffusion and related techniques.

2.     Enchant is a multitask and multimodal transformer model, trained at scale on a wide variety of biomedical data.

 

KEY RESPONSIBILITIES

  • Execute the full machine learning project cycle including planning, proof of concept, deployment, and maintenance of machine learning models

  • Perform individual and group research in the machine learning literature

  • Implement, train, evaluate, and deploy large transformer models

  • Maintain, refactor, package, and test code related to machine learning activities

  • Train new employees and interns in the practice of machine learning, including implementation, execution, evaluation, and deployment

  • Train machine learning models on many-GPU clusters

  • Communicate results with internal drug discovery teams and externally at conferences 

QUALIFICATIONS

Required:

  • A wide-ranging knowledge base in machine learning with expertise in the application of deep learning to the biology, medicine, and/or chemistry

  • A PhD or equivalent degree in machine learning or a computational STEM field

 

For the NeuralPLexer role:

  • Responsibility: Collaborate with teams of computational scientists, biologists, and medicinal chemists to apply machine learning to structural biology and structure-based drug design problems

  • Previous experience: machine learning for biomolecular structure prediction, diffusion/flow-matching/normalizing flows/neural ODEs, equivariant models, application of deep learning to the physical sciences, computational protein simulation

 

For the Enchant role:

  • Previous experience at the intersection of deep learning, python programming, and high-performance computing

  • Previous experience in large language or transformer model, including data preparation, training, finetuning, and evaluation

ABOUT IAMBIC THERAPEUTICS

Founded in 2019 and headquartered in San Diego, California, Iambic Therapeutics is disrupting the therapeutics landscape with its unique AI-driven drug-discovery platform. Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters with strong track records of success in delivering clinically validated therapeutics. The Iambic platform has been demonstrated to deliver high-quality, differentiated therapeutics to clinical stage with unprecedented speed and across multiple target classes and mechanisms of action. The Iambic team is advancing an internal pipeline of clinical assets to address urgent unmet patient needs. Learn more about the Iambic team, platform, and pipeline at iambic.ai.

MISSION & CORE VALUES

The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

ALSO

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life Insurance, 401K matching, and unlimited vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

Average salary estimate

$125000 / YEARLY (est.)
min
max
$100000K
$150000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

What You Should Know About Research Data Scientist II/Sr Research Data Scientist, Iambic Therapeutics, Inc

At Iambic Therapeutics, we're on the lookout for a Research Data Scientist II/Sr Research Data Scientist to join our innovative team in sunny San Diego. We're harnessing the power of AI to reshape the drug discovery process, and your expertise in machine learning could play a pivotal role in our journey. In this role, you will dive into cutting-edge machine learning projects, focusing on either the NeuralPLexer model, a revolutionary protein-ligand structure prediction system, or Enchant, our advanced multitask transformer model that integrates a diverse array of biomedical data. Your responsibilities will include the full machine learning project cycle, from planning and proof of concept to deployment and maintenance. You’ll encourage collaboration among computational scientists, biologists, and medicinal chemists, ensuring that machine learning applications effectively address challenges in structural biology and drug design. If you have a PhD or equivalent in machine learning or a computational STEM field, we want to see your passion for applying deep learning to our biology and medicine challenges. Plus, your experience with large transformer models and many-GPU clusters will help us continue pushing the envelope of what's possible in therapeutics. Join us at Iambic Therapeutics, where we’re not just creating a workplace; we're fostering a vibrant community aimed at making a difference in healthcare through AI-driven innovations.

Frequently Asked Questions (FAQs) for Research Data Scientist II/Sr Research Data Scientist Role at Iambic Therapeutics, Inc
What are the key responsibilities of a Research Data Scientist II/Sr Research Data Scientist at Iambic Therapeutics?

As a Research Data Scientist II/Sr Research Data Scientist at Iambic Therapeutics, you'll be responsible for executing the complete machine learning project lifecycle, developing and deploying models like NeuralPLexer and Enchant, and collaborating with internal teams for effective communication of results. Additionally, you'll perform research in machine learning literature, refactor and package code, and train new employees in machine learning practices.

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What qualifications are required for the Research Data Scientist II/Sr Research Data Scientist position at Iambic Therapeutics?

To qualify for the Research Data Scientist II/Sr Research Data Scientist role at Iambic Therapeutics, you should hold a PhD or an equivalent degree in machine learning or a computational STEM field. A strong background in deep learning as it pertains to biology, medicine, or chemistry is also essential, along with experience in applying machine learning techniques to structural biology or drug design problems.

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How does Iambic Therapeutics support continuous learning for Research Data Scientists?

Iambic Therapeutics fosters an environment of continuous learning by allowing Research Data Scientists to conduct individual and group research in the machine learning field. In addition, you'll also have the chance to train new employees, thereby reinforcing your own knowledge while sharing insights on machine learning methodologies and practices.

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What can Research Data Scientists expect regarding project involvement at Iambic Therapeutics?

Research Data Scientists at Iambic Therapeutics can expect to be deeply involved in significant projects that shape the future of drug discovery. You will have the chance to work on pioneering models, engage in collaborative brainstorming sessions with multidisciplinary teams, and even present your findings at external conferences, furthering your career and contributing to groundbreaking advancements.

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What makes Iambic Therapeutics a unique place to work for Research Data Scientists?

Iambic Therapeutics is unique in its commitment to diversity and inclusion, creating an enriching environment where various backgrounds and experiences fuel innovation. Along with competitive pay and generous benefits, our state-of-the-art facility in San Diego provides amenities designed for enhancing work-life balance, ensuring our Research Data Scientists feel valued and motivated.

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Common Interview Questions for Research Data Scientist II/Sr Research Data Scientist
What experience do you have with neural and transformer models in machine learning?

Highlight your relevant hands-on experience with neural and transformer models by discussing specific projects where you've successfully implemented, trained, and evaluated these models. Include details about the specific tasks you undertook, the data sets you worked with, and the outcomes you achieved.

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Can you explain the differences between NeuralPLexer and Enchant models?

When asked about the differences, provide a concise explanation of both models. Emphasize that NeuralPLexer focuses on protein-ligand structure prediction using equivariant diffusion techniques, while Enchant is a multitask transformer model trained on a vast range of biomedical data. This shows your understanding of how each model operates and its intended application.

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How do you approach training and evaluating large-scale models?

Share your approach to training large-scale models, detailing the methodologies you use for data preparation, model selection, hyperparameter tuning and evaluation metrics. Discuss challenges you've overcome and any specific tools or frameworks you've applied to make the process smoother.

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Describe a project where you applied deep learning to solve a biological or chemical problem.

Choose a relevant project and describe the problem, your role in it, the techniques you utilized, and the impact of the solution. Be specific about how deep learning was pivotal in achieving favorable results, illustrating your capability to apply technical skills to real-world scientific challenges.

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What techniques do you use to communicate complex results to non-technical stakeholders?

Discuss strategies for breaking down complex machine learning outcomes into digestible insights. For example, you might use visualizations, relatable analogies, or executive summaries to help non-technical team members understand your findings and how they apply to their work.

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How do you stay current with advancements in machine learning and AI?

Demonstrate your commitment to professional growth by discussing specific journals, blogs, or conferences you follow. Mention any relevant courses you've completed or groups you participate in, as this reflects a proactive approach to staying updated in a fast-paced field.

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What challenges have you faced when implementing machine learning in a research setting, and how did you overcome them?

Highlight specific challenges related to data quality, model performance, or collaboration with cross-functional teams. Discuss the steps you took to analyze and address these issues, demonstrating your problem-solving and critical thinking skills.

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Describe how you would handle a situation where team members have differing opinions on a project's direction.

Address this scenario by outlining your approach to facilitating constructive discussions. Emphasize listening to all viewpoints, summarizing key arguments, and guiding the team towards a consensus that aligns with overall project goals, showcasing your teamwork and leadership skills.

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What strategies do you employ for ensuring code quality and maintainability in your machine learning projects?

Explain your approach toward establishing coding standards, implementing regular code reviews, and utilizing version control systems. Highlight any tools or practices you use to facilitate testing and documentation, illustrating your commitment to maintaining high code quality.

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In your opinion, what role does ethics play in machine learning research?

Discuss the importance of ethical considerations in machine learning, particularly concerning data privacy and algorithmic bias. Emphasize the responsibility of scientists to ensure their work promotes fairness and transparency while addressing potential societal impacts.

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DATE POSTED
January 4, 2025

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