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Postdoctoral Research Fellow- Modeling Systems Pharmacology & Obesity Research

Job Description

Be a part of the legacy: Postdoctoral Research Fellow Program

Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

Position Overview:

The Quantitative Pharmacology and Pharmacometrics (QP2) Department of our company's Research Laboratories in Rahway, NJ is seeking a curious and collaborative Postdoctoral Scientist with a strong interest to develop quantitative models of biological systems.  The successful candidate is eager to learn and not intimidated by tough scientific challenges.  You will build a mechanistic mathematical model based on publicly available information that integrates key pharmacological and physiological pathways to quantitatively understand the interplay among pathways involved in the regulation of body weight and body composition.  Such a model enables prioritization of potential anti-obesity drugs with different modes of action based on projected clinical benefit and provide means to explore favorable drug combinations.  Furthermore, it could be used to explore the impact of different background therapies in clinical obesity trials.  The postdoctoral scientist will have the opportunity to work in collaboration with data scientists and modelers, biologists and clinicians at our company's Laboratories.

Responsibilities include but are not limited to:

  • Develop a quantitative systems pharmacology (QSP) model of key pathways regulating body weight and body composition in obesity

  • Conduct literature searches to inform key pathways and identify relationships between components in the model

  • Qualify the model with existing clinical data

  • Perform simulations and sensitivity analyses

  • Collaborate across the scientific network within our company's laboratories

  • Invest in your professional and scientific development

  • Attend and actively participate to our company's and external scientific symposiums and meetings/seminars

  • Write and review publications and manuscripts

Education Minimum Requirement:  

  • Candidates must currently hold a PhD or equivalent in PK/PD, pharmaceutical sciences, pharmacometrics, mathematics, data science, statistics/ biostatistics, computational biology/chemistry, chemical/biomedical engineering or related field or will have completed your PhD by May 1, 2025

Required Experience and Skills: 

  • A strong passion for science and exited to learn new things

  • A Ph.D. or equivalent degree in PK/PD, pharmaceutical sciences, pharmacometrics, mathematics, data science, statistics/ biostatistics, computational biology/chemistry, or chemical/biomedical engineering

  • Mathematical [or mechanistic] modeling of biological systems using R, Matlab, or other similar programing language

  • Proficiency in written and verbal communication

Preferred Experience and Skills:

  • Knowledge of obesity or other cardiometabolic diseases

  • Experience with software as mrgSolve, Simbiology (Matlab), or others

  • Skills in experimental design, mathematical problem solving, critical data analysis/interpretation, or statistics

Under New York City, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.

Expected salary range:

$75,000.00-$86,000.00

Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here. 

PostdoctoralOpportunities

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Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace.  All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

n/a

Job Posting End Date:

04/7/2025

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Average salary estimate

$80500 / YEARLY (est.)
min
max
$75000K
$86000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

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Full-time, hybrid
DATE POSTED
April 2, 2025

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