Job Description
Be a part of the legacy: Postdoctoral Research Fellow Program
Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
Position Overview:
The Quantitative Pharmacology and Pharmacometrics (QP2) Department of our company's Research Laboratories in Rahway, NJ is seeking a curious and collaborative Postdoctoral Scientist with a strong interest to develop quantitative models of biological systems. The successful candidate is eager to learn and not intimidated by tough scientific challenges. You will build a mechanistic mathematical model based on publicly available information that integrates key pharmacological and physiological pathways to quantitatively understand the interplay among pathways involved in the regulation of body weight and body composition. Such a model enables prioritization of potential anti-obesity drugs with different modes of action based on projected clinical benefit and provide means to explore favorable drug combinations. Furthermore, it could be used to explore the impact of different background therapies in clinical obesity trials. The postdoctoral scientist will have the opportunity to work in collaboration with data scientists and modelers, biologists and clinicians at our company's Laboratories.
Responsibilities include but are not limited to:
Develop a quantitative systems pharmacology (QSP) model of key pathways regulating body weight and body composition in obesity
Conduct literature searches to inform key pathways and identify relationships between components in the model
Qualify the model with existing clinical data
Perform simulations and sensitivity analyses
Collaborate across the scientific network within our company's laboratories
Invest in your professional and scientific development
Attend and actively participate to our company's and external scientific symposiums and meetings/seminars
Write and review publications and manuscripts
Education Minimum Requirement:
Required Experience and Skills:
A strong passion for science and exited to learn new things
A Ph.D. or equivalent degree in PK/PD, pharmaceutical sciences, pharmacometrics, mathematics, data science, statistics/ biostatistics, computational biology/chemistry, or chemical/biomedical engineering
Mathematical [or mechanistic] modeling of biological systems using R, Matlab, or other similar programing language
Proficiency in written and verbal communication
Preferred Experience and Skills:
Knowledge of obesity or other cardiometabolic diseases
Experience with software as mrgSolve, Simbiology (Matlab), or others
Skills in experimental design, mathematical problem solving, critical data analysis/interpretation, or statistics
Under New York City, Colorado State, Washington State, and California State law, the Company is required to provide a reasonable estimate of the salary range for this job. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.
Expected salary range:
$75,000.00-$86,000.00
Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here.
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Current Employees apply HERE
Current Contingent Workers apply HERE
US and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
Pay Transparency Nondiscrimination
We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
10%Flexible Work Arrangements:
HybridShift:
Not IndicatedValid Driving License:
NoHazardous Material(s):
n/aJob Posting End Date:
04/7/2025*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
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