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Associate Scientist, Biologics Cell Line Development (Contractor)

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform––from cells to software––to enable the design and manufacture of next-generation therapeutics.


We are seeking an Associate Scientist to join our Cell Line Development team on a 6 month contract to help push the boundaries of biotherapeutic cell line development. In this role, you will conduct CHO-based cell line engineering and screening to produce human therapeutics. In addition, you will execute synthetic biology studies and new technology evaluations to continuously innovate our workflows and expression platform. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.


About the Role:
  • Perform CHO cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment.
  • Complete comprehensive documentation of studies in an Electronic Lab Notebook (ELN).
  • Help identify emerging practices for biologics cell line development and manufacturing to shape scientific strategies and develop improved workflows.
  • Contribute to innovation focused on the development of novel cell line development workflows and applications.
  • This role will begin as a full-time, 6 month contract. Dependent on business needs, there is potential for the contract to be extended or converted into a permanent position.


About You:
  • You have a BS or MS. in Biological Engineering, Cell Biology, Molecular Biology, or a related field with 3+ years of hands-on industry experience performing CHO cell line development in support of biologic (mAb) therapies.
  • You’re a creative problem solver and get excited about the opportunity to drive the creation of industry-disruptive technology.
  • You have experience with spreadsheets such as Google Sheets or Excel and ideally Spotfire, Google Apps Script (JavaScript) and/or BigQuery to facilitate data management and analysis.
  • Don’t let this stop you from applying, but it’s a plus if you are familiar with cell culture liquid handling automation, ambr bioreactors, and/or ddPCR.


We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

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What You Should Know About Associate Scientist, Biologics Cell Line Development (Contractor), Asimov

At Asimov, we are on a thrilling mission to enhance humanity's capability to design living systems, creating groundbreaking biotechnologies that have a profound societal impact. We are currently searching for an Associate Scientist in Biologics Cell Line Development to join our vibrant team in Boston, MA, on a six-month contract. This role is pivotal as you will be instrumental in advancing biologic therapies by performing CHO-based cell line engineering and screening designed to produce human therapeutics. You'll leverage state-of-the-art equipment for transfection, cloning, and characterization while ensuring meticulous documentation through our Electronic Lab Notebook (ELN). This isn’t just a job; it's an opportunity to innovate and guide the future of biological engineering. The ideal candidate holds a BS or MS in Biological Engineering, Cell Biology, or Molecular Biology and has at least three years of hands-on experience in CHO cell line development. Creativity and problem-solving are key—you're not just filling a role; you're contributing to industry-disrupting technology, continuously seeking to improve workflows and strategies. Familiarity with tools like Google Sheets or Excel, and ideally with automation technologies is a bonus. Asimov cultivates a diverse culture of recombination, and this is your chance to grow with us in an ever-evolving field. Join us as we push the boundaries of synthetic biology and change the world together!

Frequently Asked Questions (FAQs) for Associate Scientist, Biologics Cell Line Development (Contractor) Role at Asimov
What are the primary responsibilities of an Associate Scientist at Asimov?

As an Associate Scientist at Asimov, your primary responsibilities will involve performing CHO cell line development processes including transfection, cloning, and characterization, which are essential for producing human therapeutics. You'll also document your studies comprehensively using an Electronic Lab Notebook (ELN) and contribute to the continuous innovation of workflows and scientific strategies in biologics cell line development.

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What qualifications do I need to become an Associate Scientist at Asimov?

To be an Associate Scientist at Asimov, you should possess a BS or MS in Biological Engineering, Cell Biology, Molecular Biology, or a related field, with at least three years of hands-on experience in CHO cell line development, particularly supporting biologic therapies such as monoclonal antibodies (mAb). Being well-versed in data management tools and having a creative approach to problem-solving will also greatly benefit your application.

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How does the team culture at Asimov foster innovation for the Associate Scientist role?

At Asimov, the culture is one of recombination, believing diverse backgrounds and perspectives lead to groundbreaking innovation. As an Associate Scientist, you’ll be encouraged to bring forth your unique ideas and work collaboratively, making this an ideal environment for driving the creation of disruptive technologies in biological engineering.

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Is there potential for contract extension or permanent position as an Associate Scientist at Asimov?

Yes, the Associate Scientist position at Asimov starts as a full-time, six-month contract with the potential for extension or conversion into a permanent role, depending on business needs and your performance. This provides a pathway for you to grow within the company as the team continues to evolve.

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What tools and technologies will I use as an Associate Scientist at Asimov?

As an Associate Scientist at Asimov, you will work with a range of tools and technologies, including CHO cell culture systems, data management tools like Google Sheets or Excel, and potentially automation technologies. Familiarity with Spotfire, Google Apps Script (JavaScript), or ddPCR is a plus, as these technologies facilitate efficient data handling and analysis within your role.

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Common Interview Questions for Associate Scientist, Biologics Cell Line Development (Contractor)
Can you describe your experience with CHO cell line development?

When answering this question, be specific about the techniques you used in CHO cell line development. Discuss your roles in transfection, cloning, and any innovations you contributed to in previous projects, highlighting your problem-solving skills and how you approached challenges.

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How do you ensure accuracy and compliance in your lab documentation?

It's crucial to stress the importance of thorough documentation in a lab setting. Describe your methods for maintaining accurate records in an Electronic Lab Notebook (ELN) and how you’ve implemented practices to ensure your data is always complete and compliant with industry standards.

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What strategies do you use to stay updated on new technologies in biologics development?

Discuss how you keep abreast of advancements in biologics cell line development, such as attending industry conferences, participating in webinars, or reading relevant scientific literature. Your commitment to continuous learning is valuable in this fast-paced field.

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Can you provide an example of a challenging problem you faced in cell line development, and how you resolved it?

Use the STAR method (Situation, Task, Action, Result) to describe a specific challenge you faced, the steps you took to analyze and address it, and the positive results that followed. This shows your problem-solving ability and proactive nature.

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What role does teamwork play in successful biologics cell line development?

Emphasize that teamwork is fundamental in a scientific setting. Share examples of how you’ve collaborated with your colleagues from diverse backgrounds to achieve shared goals, showcasing your communication skills and willingness to listen to others' ideas.

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How do you handle failure or unexpected results in your experiments?

Explain that failure is part of the scientific process. Discuss how you analyze results critically and learn from them to refine your approach, enhancing your experimental design and improving future outcomes.

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What is your experience with automation in cell culture processes?

Here, detail any direct experiences you have with automation technologies, such as liquid handling systems or bioreactors. If you don't have direct experience, express your understanding of automation's importance in increasing efficiency and accuracy.

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How do you prioritize tasks when managing multiple projects?

Illustrate your organizational skills by describing your methods for prioritizing tasks, such as using project management tools, setting clear deadlines, and maintaining open communication with team members about deadlines and responsibilities.

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Why are you interested in working for Asimov?

Express genuine enthusiasm for Asimov's mission to innovate biological engineering. Mention any specific projects or technologies from Asimov's portfolio that resonate with your interests, demonstrating your knowledge of the company and alignment with its goals.

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What skills do you believe are essential for an Associate Scientist at Asimov?

Mention skills like analytical thinking, attention to detail, and proficiency in laboratory techniques. Additionally, emphasize the importance of creativity in problem-solving, communication abilities, and experience with relevant software tools as key to success in this role.

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Contract, on-site
DATE POSTED
March 23, 2025

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