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Automation Engineer II, Clinical Biomarker Laboratory Operations

The Role

Moderna is seeking a talented, experienced, and motivated Automation Engineer II to join the Clinical Biomarker Laboratory to serve as a technical expert for the automation of biomarker assays.  The individual will work with automation engineers from other departments to implement existing automation strategies to optimize instruments and integration platforms in the clinical biomarker laboratory.  The candidate will provide support to laboratory scientists by automating manual laboratory processes and improving existing processes using liquid handlers, cell culture incubators and other lab automation tools.  The incumbent will also be responsible for providing critical automation support used for high-throughput assay development, qualification/validation of methods, sample management and testing.  In addition, the incumbent will be responsible for the training of team members to perform automated bioanalytical work and maintain clinical testing continuity to support Moderna’s clinical phase studies.  The ability to effectively communicate across multi-disciplinary teams and external partners is required.  The incumbent will stay aware of the latest technology, should be an outstanding automation scientist, a collaborative team member, and an excellent communicator to support Moderna’s portfolio needs.  The applicant will report to the Associate Director, Automation Engineer, Clinical Biomarker Laboratory Operations.

Here’s What You’ll Do

  • Develop and optimize new liquid handler protocols for the screening and high-throughput assay platforms, specifically using Hamilton Venus 

  • Work with scientist to develop, optimize and implement automated workflows

  • Perform lab automation operations including protocol design, error recovery, point-teaching etc

  • Drives software communication drivers between lab automation systems

  • Deploy integrated lab automation solutions based on dynamic scheduling systems

  • Assist scientists with operation of automation platforms including design, qualification/validation, and implementation of automated bioanalytical methods

  • Track/record problems with the automated systems and assay setups for proper troubleshooting

  • Explore, evaluate, and implement newer hardware and Digital control technologies in automation, to improve on clinical sample analysis such as robotic arm and modular platforms

  • Develop and optimize new liquid handler protocols for the high-throughput assay platforms, specifically using Hamilton automated liquid handling systems

  • Identify digital solutions to integrate robotic and modular platforms solutions

  • Train users on new methods and protocols of system functionalities to automate bioanalytical processes using automated liquid handling and other modular platforms

  • Educate users about lab automation instruments, software and their capabilities

  • Collaborate and coordinate with internal and external groups to identify appropriate solutions to improve bioanalytical testing capacity and efficiency

  • Occasionally the job may require overtime work or weekend shift as needed

  • Additional duties as may be assigned from time to time

Here’s What You’ll Need (Minimum Qualifications)

  • Requires MSc or B.S. in biology/engineering/biotechnology or related field

  • Minimum 3 years’ experience in bioanalytical laboratory and automation solutions

Here’s What You’ll Bring to the Table (Preferred Qualifications)

  • Experience in Java, C++ and other object-oriented programming languages

  • Experience with LIMS systems or database

  • 2 years of extensive Hamilton liquid handlers servicing and troubleshooting experience strongly preferred.

  • Requires ability to diagnose problems and fix problems with Hamiltons

  • Background in Web Services (SOAP,REST), JMS, J2EE and/or Spring frameworks

  • Must be able to work in a fast-paced multi-tasking environment

  • Must demonstrate an ability to troubleshoot complex problems on automation equipment

  • Experience with Tecan, Hudson, High-Res, Echo, Spinnaker or Inspire™ module is desirable

  • Experience with dynamic scheduling software: Momentum, SmartQC, Cellario, GreenButtonGo, Softlynx, Retisoft,or similar

  • Extensive hands-on experience with high throughput liquid handling system operation, troubleshooting, and maintenance

  • Industry experience focused on lab automation is strongly preferred

  • Proven ability to successfully automate manual lab processes

  • Keen on taking initiative, ability to work independently as well as in team settings, and the ability to execute on strategic plan under minimal supervision

  • Will have an analytical mindset, creative problem-solving skills, and be methodical and organized

  • Experience and skills in creating, modifying, and troubleshooting robotics/automation scripts

  • Exceptional written and oral communication

  • Familiarity with Atlassian tools (e.g., Bitbucket, Jira) is desirable

  • Experience with Scrum/Agile development methodologies

  • Ability to communicate at various levels within the organization as well as with external vendors

  • Be able to travel upon need 5%

  • A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

  • This position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote work.

At Moderna, we believe that when you feel your best, you can do your best work.  That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

  • Best-in-class healthcare coverage, plus a suite of voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Lifestyle Spending Accounts to personalize your well-being journey
  • Family planning and adoption benefits
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investment opportunities
  • Location-specific perks and extras

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.  

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. 

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. 

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. 

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. 

Moderna is a smoke-free, alcohol-free, and drug-free work environment. 

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! 

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.  

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements. 

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. 

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com.  (EEO Employer)  

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What You Should Know About Automation Engineer II, Clinical Biomarker Laboratory Operations, Moderna

If you're passionate about automation in the biotech space, then the role of Automation Engineer II at Moderna in Norwood, Massachusetts, could be your next exciting adventure! As an Automation Engineer II, you'll become a key player in the Clinical Biomarker Laboratory, working alongside a talented team to automate and enhance laboratory processes. Your day-to-day will involve developing and optimizing new liquid handling protocols, implementing automation strategies, and supporting high-throughput assay development. You'll get hands-on with cutting-edge technologies including Hamilton automated liquid handling systems while collaborating with scientists to streamline workflows. But it's not just about the tech—your communication skills will shine as you engage with multi-disciplinary teams and external partners to drive impactful results. With a focus on continuous improvement and training team members on automated bioanalytical methods, you'll play a crucial role in maintaining clinical testing continuity for Moderna's innovative clinical phase studies. This role is perfect for someone who is not just technically proficient but also eager to make a difference in a fast-paced, collaborative environment. If you want to be part of a company recognized as a leader in mRNA technology and committed to innovative health solutions, we invite you to apply today!

Frequently Asked Questions (FAQs) for Automation Engineer II, Clinical Biomarker Laboratory Operations Role at Moderna
What are the main responsibilities of an Automation Engineer II at Moderna?

As an Automation Engineer II at Moderna, your primary responsibilities include developing and optimizing automated workflows, designing liquid handling protocols, and supporting high-throughput assay development in the Clinical Biomarker Laboratory. You'll work closely with laboratory scientists to enhance existing processes and troubleshoot any automation challenges, ensuring smooth operations in line with Moderna's commitment to innovation in medicine.

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What qualifications are required for the Automation Engineer II role at Moderna?

To be considered for the Automation Engineer II position at Moderna, you should possess a MSc or B.S. degree in biology, engineering, biotechnology, or a related field. A minimum of 3 years of experience in a bioanalytical laboratory and expertise in laboratory automation solutions are essential. Additionally, proficiency in programming languages such as Java or C++, as well as hands-on experience with Hamilton liquid handlers, is strongly preferred.

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What skills should an ideal candidate have for the Automation Engineer II position at Moderna?

An ideal candidate for the Automation Engineer II position at Moderna should have strong technical skills in lab automation systems, excellent problem-solving abilities, and outstanding written and oral communication skills. The ability to troubleshoot complex automation equipment and manage multiple tasks in a fast-paced environment is critical, as well as familiarity with Agile methodologies and experience with automation-related scripting.

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How does Moderna support career growth for Automation Engineer II?

At Moderna, career growth for an Automation Engineer II is supported through continuous learning opportunities, mentoring, and exposure to cutting-edge technology in the biotech industry. The company's emphasis on teamwork enables you to collaborate with experts across various fields, enhancing your skills and career trajectory while you contribute to revolutionary advancements in medicine.

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Is the Automation Engineer II role at Moderna remote or in-person?

The Automation Engineer II position at Moderna is site-based, requiring full-time presence at the Norwood, Massachusetts location. This in-person model fosters collaboration and innovation, key elements that contribute to Moderna's success in developing novel therapeutics.

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Common Interview Questions for Automation Engineer II, Clinical Biomarker Laboratory Operations
Can you describe your experience with liquid handlers?

In answering this question, focus on specific experiences you've had with liquid handlers, such as the Hamilton systems mentioned in the job description. Detail your knowledge of protocol design, optimization, and troubleshooting, and provide examples of how you successfully implemented higher throughput capabilities in your past roles.

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What automation challenges have you faced and how did you solve them?

Prepare to discuss a specific challenge you encountered in lab automation, detailing the steps you took to analyze the problem, your troubleshooting process, and the final solution. Highlight how your technical skills and team collaboration contributed to overcoming the issue.

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How do you prioritize tasks in a fast-paced environment?

Demonstrate your ability to prioritize tasks by explaining your methods for assessing urgency and importance. Talk about tools or strategies you use to manage your workload effectively, and provide examples of how you've successfully met deadlines without compromising quality.

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Describe a project where you collaborated with scientists to automate workflows.

Share a specific project experience where you worked alongside scientists to automate workflows. Emphasize your role, the technologies involved, and the project's impact on operational efficiency. Highlight aspects like your communication and teamwork skills that made the collaboration successful.

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What digital control technologies are you familiar with?

In your answer, discuss any experience you have with digital control technologies relevant to laboratory automation. Mention specific systems you've worked with, such as robotic arms or modular platforms, and describe how you’ve implemented them in previous projects to enhance analytical capabilities.

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How do you keep up with the latest advancements in lab automation?

Indicate how you stay informed on trends and technologies in lab automation, such as attending conferences, following relevant publications, and engaging with professional networks. This shows your proactive approach to continuous learning in your field.

Join Rise to see the full answer
What programming languages do you utilize for automation scripting?

List the programming languages you are proficient in, especially those mentioned in the job description like Java and C++. Discuss a project where you utilized these languages to script automation processes, emphasizing your coding skills and the successful outcomes.

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How do you ensure adherence to quality and regulatory standards in automation?

Detail your approach to ensuring quality and compliance in automation projects, including familiarity with regulatory requirements. Talk about experiences where you ensured that lab automation procedures adhered to these standards, highlighting your attention to detail and commitment to excellence.

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Explain how you trained other team members on automation systems.

Discuss your experience in training others, emphasizing your ability to convey complex concepts simply and effectively. Provide specific instances where you developed training materials, conducted workshops, or offered hands-on support to colleagues in using lab automation systems.

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What strategies do you employ for troubleshooting automated systems?

Share your systematic approach to troubleshooting, from identifying problems through diagnostics to implementing solutions. Highlight your analytical mindset and any specific tools or methodologies you use to ensure minimal downtime in automated processes.

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DATE POSTED
April 2, 2025

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