Director, DMPK

As the Director, DMPK at Septerna, your main responsibilities include setting and overseeing the DMPK strategy, designing studies to evaluate drug absorption and interactions, and managing cross-functional project teams to ensure successful drug discovery initiatives. This role empowers you to steer early-stage project screening all the way through to candidate selection and possibly early clinical development.

Candidates applying for the Director, DMPK position at Septerna should possess contemporary expertise in modern DMPK approaches, extensive experience in drug discovery across multiple target classes, and an ability to design studies for drug absorption and stability. Team leadership skills, along with a strong background in collaborating with external research organizations, are also crucial.

At Septerna, the work environment for the Director, DMPK is dynamic and fast-paced, fostering collaboration among a multidisciplinary team. We encourage innovation and the sharing of ideas, creating a supportive atmosphere for personal and professional growth. You'll be working alongside passionate individuals all dedicated to the mission of developing meaningful therapeutics.

Septerna is committed to the professional growth of its employees, including for the Director, DMPK. We offer opportunities for mentorship, collaboration on innovative projects, and access to continued learning through industry conferences and workshops. Your development is essential to our mission, and we provide resources to help you thrive.

The anticipated salary range for the Director, DMPK position at Septerna is between $220,000 and $240,000, depending on experience, skills, and education. Besides competitive salary, we offer a comprehensive benefits package, including stock options and an annual target bonus as part of our commitment to employee well-being and satisfaction.

When answering this question, highlight specific DMPK strategies you've developed or implemented in prior roles. Discuss the importance of aligning these strategies with drug discovery phases and how they contributed to successful project outcomes.

In your response, share examples where you've effectively worked with diverse teams, emphasizing communication techniques and how you align objectives across departments, ensuring a unified approach during project timelines.

Describe the types of preclinical studies you’ve designed, stressing your hands-on experience with specific methodologies and insights gained from the data that shaped drug discovery pathways.

Outline your mentoring philosophy, including how you foster a supportive environment that encourages knowledge sharing and professional development, ensuring your team remains motivated and productive.

Share your approach to overseeing external teams, focusing on how you ensure project goals are met and fostering strong working relationships that contribute to successful drug discovery initiatives.

Be prepared to discuss specific challenges, detailing your problem-solving strategies and the alignment of your solutions with project timelines and scientific goals.

Clearly articulate the complexities involved in drug absorption, including factors such as solubility, permeability, and formulation, and how understanding these elements guides strategy in initial drug discovery stages.

Mention specific journals, conferences, and online resources you follow to stay abreast of changes in DMPK science, demonstrating your commitment to continuous learning and application of new knowledge in your role.

Discuss your familiarity with emerging technologies like computational modeling and high-throughput screening, illustrating how these tools enhance decision-making and efficiency in drug discovery processes.

Highlight qualities such as strong leadership, excellent communication skills, adaptability, and a collaborative spirit that are essential for guiding teams and projects toward successful therapeutic outcomes.