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Senior Scientist, Flow Cytometry

Senior Scientist, Flow Cytometry

Summary of the Group 

The Flow Cytometry group is part of Dynamic Omics/ Centre for Genomics Research (CGR) and Discovery Sciences within AstraZeneca, and work across all therapeutic areas: Oncology, Cardiovascular, Renal and Metabolism (CVRM), Respiratory and Immunology (R&I), Vaccines and Immunotherapies (V&I), and Rare Diseases. The team supports over 600 scientists globally and delivers key data to projects across all phases of the drug discovery and development, and we work with all modalities from small molecules to biologics. The Flow Cytometry Center of Excellence is among the leading flow cytometry organizations worldwide (as recently recognized by the International Society for Advancement of Cytometry), equipped with state-of-the-art instrumentation and cutting-edge technology and expertise. 

Introduction to role

In this role, you will support the operations of the team in Gaithersburg, MD, with a particular focus on flow cytometry core lab experience and cell sorting. You will also participate in collaborations with multiple therapeutic areas. The successful candidate will have the opportunity to work and grow in a fast-paced environment under the supervision of senior staff members.

Accountabilities

In this role, you will serve as a primary resource to:

  • Support the daily operation and maintenance of flow cytometers with a specific focus on cell sorting, and ensure accurate acquisition and management of data under local and global flow cytometry leadership

  • Collaborate on innovative immunology/flow cytometry projects and/or automation solutions to support Oncology and BioPharma within AstraZeneca

  • Be an expert in multicolor flow cytometry, review and analyze data, interpret experimental results, and summarize data for presentations and reports with accountability for accuracy

  • Contribute to the development of new technological platforms such as Imaging Flow Cytometry

  • Demonstrate excellent collaborative and pro-active problem-solving skills to include identifying a problem and taking appropriate actions and knowing when to seek guidance

Essential Skills/Experience

  • PhD degree (or equivalent experience) in Immunology, Bioinformatics, Engineering or a related quantitative discipline and 3+ years of relevant experience, or a Masters with 5+ years, or a Bachelor’s with 8 years of directly relevant outstanding performance

  • Cell sorting and flow cytometry core experience

  • Track record of scientific excellence in immunology, flow cytometry and/or automation

  • High-content and/or spectral flow cytometry experience

  • Experience with a variety of flow cytometry data analysis and bioinformatic tools, including FlowJo, FCS Express, OMIQ, or Cytobank

  • Great teamwork and communication skills, both verbal and written

  • Strong multi-tasking, time management and organizational skills

Desirable Skills/Experience

  • Programming skills such as Python and R are desirable

  • Experience in automation is desirable

  • Experience in understanding and analyzing other omics data (e.g. transcriptomics, mass spec) is a plus

  • Microscopy experience is desirable

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. 

At AstraZeneca, we are at the forefront of creating new solutions that put patients at the core. We harness digital, data, and analytics to reimagine healthcare's future and deliver improved outcomes beyond core medicine. Our collaborative culture drives innovation, empowering us to unleash creativity and bring modern approaches to everyday challenges. Join us as we push boundaries within regulatory limits, leveraging technology to redefine patient experiences across their entire journey.

Ready to make a difference? Apply now to join our team!

The annual base pay (or hourly rate of compensation) for this position ranges from $108,473 to $162,710. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

11-Apr-2025

Closing Date

24-Apr-2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
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Average salary estimate

$135591.5 / YEARLY (est.)
min
max
$108473K
$162710K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

What You Should Know About Senior Scientist, Flow Cytometry, AstraZeneca

Join the dynamic team at AstraZeneca as a Senior Scientist, Flow Cytometry, where you'll be part of the Cutting-edge Flow Cytometry group in Gaithersburg, MD. This renowned team, highly regarded within the industry, plays a pivotal role in supporting over 600 scientists globally across various therapeutic areas, including Oncology, CVRM, and Rare Diseases. Here, innovation is at the forefront, with opportunities to work on groundbreaking projects involving small molecules and biologics. As the Senior Scientist, you'll spearhead the operations of the flow cytometry core lab, ensuring the maintenance and functionality of flow cytometers while providing expert insights into cell sorting processes. Your work will involve collaboration with multiple therapeutic areas on innovative flow cytometry projects and automation solutions, contributing to AstraZeneca's vision of enhancing drug discovery and development. Your background in immunology, bioinformatics, or a related field, combined with your proficiency in multicolor flow cytometry, will be vital in interpreting experimental data and summarizing intelligence for impactful reporting. Join us and be part of a collaborative environment that values problem-solving and innovative thinking, as we aim to revolutionize healthcare solutions, putting patients at the core of everything we do.

Frequently Asked Questions (FAQs) for Senior Scientist, Flow Cytometry Role at AstraZeneca
What are the main responsibilities of a Senior Scientist, Flow Cytometry at AstraZeneca?

As a Senior Scientist in Flow Cytometry at AstraZeneca, your primary responsibilities include managing the daily operations and maintenance of flow cytometers, especially focusing on cell sorting. You'll collaborate on innovative immunology projects, leveraging your expertise in multicolor flow cytometry for data analysis, and contribute to the development of new technological platforms like Imaging Flow Cytometry.

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What qualifications are needed to be a Senior Scientist, Flow Cytometry at AstraZeneca?

To qualify for the Senior Scientist, Flow Cytometry position at AstraZeneca, candidates need either a PhD in Immunology or a related quantitative field with a minimum of 3 years' relevant experience, or a Master's degree with 5 years' experience, or a Bachelor's degree accompanied by 8 years of outstanding performance in the field, emphasizing flow cytometry and cell sorting expertise.

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What skills are essential for success as a Senior Scientist, Flow Cytometry at AstraZeneca?

Key skills for success as a Senior Scientist in Flow Cytometry at AstraZeneca include expertise in cell sorting, strong teamwork and communication abilities, and proficiency in flow cytometry data analysis. Desirable skills may also include programming knowledge in Python or R, and familiarity with omics data analysis.

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How does AstraZeneca support the growth and development of Senior Scientists in Flow Cytometry?

AstraZeneca fosters a collaborative and fast-paced environment that encourages professional growth for Senior Scientists in Flow Cytometry. You will have continuous opportunities to work alongside senior staff, participate in groundbreaking research, and contribute to diverse therapeutic projects, allowing for skill enhancement and career progression.

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What is the work culture like for a Senior Scientist, Flow Cytometry at AstraZeneca?

The work culture at AstraZeneca for a Senior Scientist in Flow Cytometry emphasizes innovation, collaboration, and diversity. The team is dedicated to creating an inclusive environment where diverse perspectives are celebrated, driving creativity and modern solutions to improve patient outcomes.

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Common Interview Questions for Senior Scientist, Flow Cytometry
Can you explain your experience with multicolor flow cytometry?

In responding to this question, provide specific examples of projects where you've utilized multicolor flow cytometry, detailing the techniques you employed and the outcomes achieved. Highlight your understanding of experimental design and how you interpreted complex data.

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What challenges have you faced in flow cytometry, and how did you overcome them?

Think of a particular challenge you've encountered, such as troubleshooting equipment or data discrepancies, and discuss the steps you took to resolve it. Include collaboration and problem-solving strategies that showcase your ability to work effectively in a team.

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How do you stay updated with the latest advancements in flow cytometry?

Mention specific resources you follow, such as scientific journals, conferences, or professional groups in flow cytometry. Explain how you actively seek continued education and apply new knowledge to your work, which reflects your commitment to scientific excellence.

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Describe a project where you collaborated with a cross-functional team.

Share an anecdote illustrating your ability to work within a cross-functional team. Emphasize your role, how you communicated with team members from different backgrounds, and the project's impact on the overall goals of the group.

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What techniques do you use for data analysis in flow cytometry?

Discuss specific software tools you have experience with, such as FlowJo or Cytobank. Explain your approach to analyzing flow cytometry data, including how you ensure accuracy and reliability in your results.

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What motivates you to work in the field of flow cytometry?

Reflect on your passion for the science behind flow cytometry and the significant role it plays in advancing healthcare. Share a personal story or experience that inspired you to pursue this career path.

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How do you prioritize tasks and manage time effectively in a busy lab environment?

Outline your strategies for time management, including setting priorities based on project deadlines, collaborating with team members to distribute workloads, and using tools to keep track of tasks that help maintain productivity in a fast-paced setting.

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What role does automation play in your flow cytometry projects?

Discuss your experience with automation in flow cytometry and how it has influenced project efficiency and accuracy. Provide examples of how you have implemented automation solutions or your interest in exploring further advancements in this area.

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How do you handle feedback and critiques on your work?

Emphasize your openness to receiving feedback. Share examples of how you've successfully incorporated constructive criticism into your work, leading to improvements in your project outcomes.

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What are your long-term career aspirations as a Senior Scientist in Flow Cytometry?

Discuss your career goals, whether it be advancing to a leadership role, contributing to innovative research, or expanding your expertise in new technologies. Articulate how the role at AstraZeneca aligns with these aspirations and your desire to make a significant impact in the industry.

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DATE POSTED
April 13, 2025

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