Associate Director/Director, Medical Affairs Strategy

Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle® Toxin Conjugate (BTC®) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle® Radio Conjugates (BRC™) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle® technology to develop therapies for diseases beyond oncology.

Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA USA

Culture is key and all Bicycle employees actively embrace and role model our company values: 

• We are Adventurous. We believe it’s the way to deliver extraordinary results for our patients.   
• We are Dedicated to our Mission. You can’t change the world if you don’t have determination. 
• We are One Team. We only succeed when we work together.  

The Associate Director/Director, Medical Affairs Strategy will function as a scientific and medical expert within Medical Affairs, as well as other groups across the company. This individual will be responsible for helping to develop and execute medical affairs strategies and tactical plans. This person will also be expected to develop relationships with Key Opinion Leaders (KOLs), professional medical organizations, and patient advocacy organizations as assigned by the Senior Director, Global Medical Affairs Strategy Lead. The candidate will have a successful track record of supporting the development and implementation of medical strategy, including the effective communication of scientific data through publications, medical communications, scientific engagement, advisory boards, congress activities, and medical information.  In addition, this individual will support activities related to data generation, life cycle management, and launch readiness activities. This individual should ideally have prior experience in the field of solid tumors, with the ability to translate scientific goals into actions that align with cross-functional partners and business objectives.

• Contribute to the creation and implementation of medical affairs strategies and tactics for assigned Bicycle assets

• Identify, develop, and cultivate trust-based relationships with professional medical organizations including medical societies and NCI-designated Cooperative Groups, as well as with patient advocacy organizations
• Support U.S. medical affairs launch readiness planning, activities, tracking, and execution
• Utilize experience, resources, and gained knowledge to affect different projects and programs across pipeline for the GMA team
• In collaboration with the Senior Director, Global Medical Affairs Strategy Lead, establish budgets for medical affairs tactics
• Work closely with the field medical affairs team as a subject matter expert to support scientific education/training and KOL activities
• Provide input to Scientific Communications/Medical Communications on internally and externally facing medical materials and publication
• In collaboration with the Medical Affairs Leadership Team, provide input, review and support for Investigator-Sponsored Trial (IST) program
• Support Global Medical Affairs lead on GPT to plan and execute on the life cycle management plan for assigned Bicycle assets

• Prior biopharmaceutical industry experience is required (4+ years of experience preferred) in medical affairs and/or oncology drug development

• Advanced degree in a health-related field (PhD, MD, and PharmD strongly preferred)
• Ability to think strategically and translate scientific information into medical affairs strategies
• Ability to understand complex information and simplify into concise scientific messages
• Ability to navigate and succeed in a dynamic environment with collaboration and teamwork
• Strong communication and presentation skills with the ability to present scientific data in a credible and fair balanced manner
• Strategic thinking with strong business acumen and the ability to prioritize
• Excellent communication and presentation skills with the ability to influence key stakeholders
• Proficiency in clinical trial data review and interpretation
• Knowledge of the U.S. healthcare and regulatory environment
• Willingness and flexibility to meet domestic and international travel requirements (up to 30%)

• Flexible working environment
• Competitive reward including annual company bonus
• Medical, dental, and vision insurance for eligible employees and their families with 100% of the premiums covered by the Company
• Health and Dependent Care Flexible Spending Accounts
• 401(k) plan with a 4% Company match and immediate vesting
• Eligibility to accrue up to 23 paid time off days per full year worked, plus the option to buy up to 5 additional days
• Employee assistance program
• Employee recognition schemes
• 10 Company holidays
• Competitive Family Leave Policy
• Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.