Research Associate III, Impurity Assays

Seagen is a global, multi-product biotechnology company dedicated to developing and commercializing transformative cancer medicines. As the industry leader in antibody-drug conjugate (ADC) technology, we pioneered a new generation in the science of harnessing antibodies to deliver cell-killing agents directly to cancer cells. Seagen’s dedication to improving the lives of cancer patients goes beyond science, and we believe that every employee has a role in contributing to this mission. By working together with a shared dedication and diverse perspectives, we are able to reach our full potential and make a real difference in the world. Seagen is a fast-growing company and has an abundance of opportunities available for you to grow your career. Put your passion to work at Seagen and join us!

Summary:

Seagen is looking for an action-oriented Research Associate III to work in the Impurity Assays Group. In this individual contributor role, the primary responsibility will be to perform testing for process-related impurities including host cell proteins (HCPs), Protein A leachate, glucan, and growth factor IGF-1 LongR3, and more. This person will also participate in development and qualification of methods using various analytical techniques to characterize process-related impurities to support our antibody and antibody-drug conjugate programs. The ideal candidate will have a strong background in biochemistry, molecular biology, or related discipline, foster a team player mentality, possess strong critical thinking and troubleshooting skills and the ability to work both independently and in a collaborative manner.

Principal Responsibilities:

• Perform process-related impurity testing with a high degree of independence in daily work
• With guidance, design and execute development and qualification of analytical assays to characterize process-related impurities, and provide method troubleshooting assistance
• Plan and execute complex experiments with guidance.
• Independently design and execute routine experiments, and compile, analyze and interpret data
• Support transfer impurity methods and reagents to internal or external teams and manufacturing facilities
• Summarize and present experimental findings at group, department or cross-functional meetings, participate in discussions and author technical reports

Required Qualifications:

• M.S. degree in biochemistry, molecular biology, microbiology or related scientific discipline with 2+ years of relevant industry experience; or B.S. degree with 5+ years of relevant industry experience
• Familiar with process development for drug manufacturing
• Proficiency in plate-based assay development and troubleshooting, including ELISAs
• Experience in developing and executing ELISAs and method qualification/validation
• Experience in gel electrophoresis and western blotting
• Strong organizational skill and attention to detail
• Demonstrated ability to understand project scope, meet deliverables timeline
• Effective communicator and interpersonal skills
• Leans into optimizing work processes

Preferred Qualifications:

• Experience with 2D gel and western blotting
• Experience with lab automation technologies
• Experience with diverse bioanalytical platforms: e.g., Gyrolab, MSD ECL, AlphaLISA, Simple Plex

As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visit www.seagen.com.

The hiring pay range for this position is $83,000 to $108,000 per year based on skills, education and experience relevant to the role. Other components of total compensation include a competitive equity grant at the time of hire (with additional annual grants, and grants upon promotion when applicable), and an annual bonus.

Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.

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