Research Technician - job 2 of 2

Job Category: Fulltime Regular
Exempt Overtime Eligible: Overtime Eligible
Benefits Eligible: Benefit Based

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.

Job Summary

We are seeking a highly motivated and dependable individual with experience in molecular biology to join our integrative computational and experimental team in characterizing the functions and mechanisms of noncoding RNAs in gene regulation. Specifically, this person will help to optimize methods and generate data for understanding interactions between RNA, DNA, and proteins in mammalian cells. This work will include experiments to characterize RNA-protein interactions and DNA-protein interactions involving library generation, high-throughput sequencing, and mass spectrometry. The candidate will work closely with other graduate students, post-doctoral fellows, and staff members in the lab to apply various technologies in specific biological applications. The candidate will adapt easily to changing needs and priorities of a fast-paced research environment, facilitate project completion, address technical issues as they arise, and will summarize and present results to the research group. Training in established techniques will be provided, but the work will require significant independence of day-to-day operations to achieve the overall goals of the project.

Essential Job Duties

• Designs and performs challenging bench level experiments and small projects.
• Adapts and optimizes methods for manipulating RNA and proteins.
• Executes established genomic protocols, including but not limited to RAP, CLIP-seq, ChIP-seq, RNA-seq.
• Generates new cell-lines using genetic engineering approaches such as CRISPR-Cas9.
• Analyzes, summarizes, and presents results to the group as needed and to senior members of the research team and lab head to ensure proper experimental design, analysis, and technical concerns related to the projects.
• Adjusts easily to changing needs and priorities in order to facilitate project completion and to address technical problems.
• Works collaboratively with others to dynamically synthesize strategies, results, and future directions for single projects or multiple projects simultaneously.

Basic Qualifications

• Bachelor's degree in biology or related field required.
• Must possess at least 2 years of experience in a research laboratory, conducting an independent project(s).
• Solid technical knowledge of molecular cloning and cell biology techniques.
• Familiarity with molecular biological methods and the operation of standard lab equipment required.
• Excellent communication skills and the ability to interact professionally with all levels of staff and with external contacts in a fast-paced environment required.
• Ability to handle a variety of tasks simultaneously required.
• Must possess a high level of initiative and the ability to work with little supervision.
• Excellent organization, time management, and project management skills.

Preferred Qualifications

• Direct laboratory experience involving molecular cloning, cell culture, library generation, proteomics, or next generation sequencing a strong plus.
• Broad knowledge of molecular biology, RNA-sequencing and DNA-sequencing methods preferred.
• Basic knowledge of sequence analysis tools such as BLAST, primer3, UCSC genome browser, and other applications favored.
• Solid technical knowledge of DNA and RNA isolation and handling techniques a plus.

Required Documents

• Resume
• Cover Letter

To be considered for this position please visit our web site and apply on line at the following link: https://hr.caltech.edu/work/job_openings

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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