Scientist - In Vitro

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Pharmaceutical Candidate Optimization organization at Bristol Myers Squibb is a dynamic, multi-disciplinary department that works to discover and optimize new drug candidates. We work across all therapeutic areas and all modalities (small molecules, biotherapeutics, gene and cell therapies and other novel modalities), and engage with all other R&D functions to advance new assets in the BMS portfolio. Our integrated, cross-functional teams apply deep expertise in drug metabolism, pharmacokinetics (DMPK), toxicology, pharmaceutics, and bioanalysis to identify and solve issues, discover high quality drug candidates, and enable their clinical development.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Position Summary

We are seeking an enthusiastic, self-motivated scientist to join our Drug Metabolism and Pharmacokinetic (DMPK) Group as a Scientist. The position is available at multiple locations within BMS (Lawrenceville, Cambridge, San Diego, Bay Area) . The role is in the Pharmaceutical Candidate Optimization (PCO) department that encompasses broad support for Discovery programs and has a diverse range of expertise in DMPK, toxicology, pharmaceutics and bioanalytical sciences.

Key Responsibilities

In this role, the selected candidate will develop, improve and perform assays to predict the DMPK profile of molecules synthesized during lead optimization in small molecule Discovery projects. The successful candidate is expected to have working knowledge of the liquid chromatography (LC) and LC-MS approaches to chemical quantitation. They will also be expected to learn how to deconvolute in vitro to in vivo correlations for DMPK endpoints; they will address key mechanistic questions leveraging state of art in vitro and in silico ADME science, including physiologically based PK modeling for programs and issues across the discovery portfolio. Depending on the level of experience and interest, the successful candidate may represent the DMPK group in Discovery project teams.

Basic Qualifications

• Bachelor's Degree and 5+ years of academic / industry experience OR

• Master's Degree and 3+ years of academic / industry experience OR

• PhD with no experience required

Preferred Qualifications

• Bachelors or Masters degree in chemistry, biology, biochemistry, or related discipline with 2-5 years of relevant experience.

• Ph.D degree in any of the same fields above

• Demonstrated problem-solving skills, critical/strategic thinking ability, and capability of integrating data across multiple sources are required.

• Hands-on experience in conducting in vitro experiments is required.

• Experience with various analytical techniques and equipment such as LC-MS/MS and LC-UV is required.

• Experience with physiologically based PK modeling software in the areas of clearance and DDI prediction is desired.

• Strong communication skills and ability to work and collaborate in a cross-functional team setting are critical for this role.

For California applicants only, the starting compensation for this job is a range from $97,000 - $135,300, plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.

Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

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If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.