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Postdoctoral Research Fellow - Neurobiology and Anatomy

The Ma lab (https://med.uth.edu/nba/2022/11/03/keran-ma-phd/) at the Department of Neurobiology and Anatomy, McGovern Medical School, University of Health Science Center at Houston is seeking a motivated and creative Postdoctoral Fellow. We aim to understand neuron-glia interactions and cellular dysfunction underlying behavioral disturbances in Alzheimer’s disease at the molecular, cellular, circuit and network levels. We are interested in understanding neuronal functional deficits and modulation of neuronal activity by microglia and astrocytes in mouse models of Alzheimer’s disease. We employ advanced state-of-the-art tools in in vivo electrophysiology (including Neuropixels probes) and multi-photon imaging in awake behaving mice, virtual reality behavioral paradigms, machine learning, and RNA sequencing to address our research questions. We use optogenetics, genetic manipulation, fluorescent calcium, voltage, and neurotransmitter biosensors as well as pharmacological intervention to visualize and modulate specific neuronal and glial functions to gain further mechanistic insight for therapeutic interventions.What we do here changes the world. UTHealth Houston is Texas’ resource for healthcare education, innovation, scientific discovery, and excellence in patient care. That’s where you come in.Once you join us you won't want to leave. It’s because we reward our team for the excellent service they provide. Our total rewards package includes the benefits you’d expect from a top healthcare organization (benefits, insurance, etc.), plus:• 100% paid medical premiums for our full-time employees• Generous time off (holidays, preventative leave day, both vacation and sick time – all of which equates to around 37-38 days per year)• The longer you stay, the more vacation you’ll accrue!• Longevity Pay (Monthly payments after two years of service)• Build your future with our awesome retirement/pension plan!We take care of our employees! As a world-renowned institution, our employees’ wellbeing is important to us. We offer work/life services such as...• Free financial and legal counseling• Free mental health counseling services• Gym membership discounts and access to wellness programs• Other employee discounts including entertainment, car rentals, cell phones, etc.• Resources for child and elder care• Plus many more!Position Summary:A biomedical postdoc position provides an opportunity for early-career researchers to gain valuable experience, develop independent research skills, and contribute to the advancement of scientific knowledge in their field of expertise.A strong background in neuroscience, neurobiology, or a related field is preferred. The successful candidate will be trained in advanced systems neuroscience tools. Experience in in vivo electrophysiology/optogenetics, in vivo multi-photon imaging, behavioral testing, and/or Matlab/Python-based data analysis is a plus.Position Key Accountabilities:1. Plans and conducts experiments, analyzes data, and prepares publications describing results.2. Assists in training and mentoring of lab personnel, including graduate students and other trainees.3. Reads and evaluates literature.4. Possess interpersonal skills to effectively collaborate and communicate with individuals at all levels.5. Have strong written and oral communication skills.6. Performs other duties as assigned.Minimum Education:Doctoral/Terminal DegreePhysical Requirements:Exerts up to 20 pounds of force occasionally and/or up to 10 pounds frequently and/or a negligible amount constantly to move objects.Security Sensitive:This job class may contain positions that are security sensitive and thereby subject to the provisions of Texas Education Code § 51.215Residency Requirement:Employees must permanently reside and work in the State of Texas.

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What You Should Know About Postdoctoral Research Fellow - Neurobiology and Anatomy, UTHealth Houston

Join the Ma lab at the McGovern Medical School of the University of Health Science Center at Houston as a Postdoctoral Research Fellow in Neurobiology and Anatomy! This exciting position is perfect for those eager to explore the intricate interactions between neurons and glial cells, focusing on the cellular dysfunctions that underlie behavioral disturbances in Alzheimer's disease. In our lab, you'll have the chance to dive into cutting-edge research, utilizing advanced tools like Neuropixels probes and multi-photon imaging to study the workings of awake behaving mice. If you’re fascinated by how microglia and astrocytes modulate neuronal activity, this is the place for you. We emphasize a collaborative environment where you can enhance your skills in in vivo electrophysiology, machine learning, and RNA sequencing. You'll also mentor graduate students while preparing impactful publications that contribute to our understanding of neurobiology. At UTHealth Houston, we care about our team's welfare, offering a generous benefits package that includes fully paid medical premiums, extensive time off, and a strong retirement plan. With fantastic resources for personal wellness and work/life balance, you'll find that this role not only advances your career but also enriches your life. Apply now to be part of an innovative team that is making a tangible difference in healthcare.

Frequently Asked Questions (FAQs) for Postdoctoral Research Fellow - Neurobiology and Anatomy Role at UTHealth Houston
What are the responsibilities of a Postdoctoral Research Fellow at the Ma lab?

As a Postdoctoral Research Fellow in Neurobiology and Anatomy at the Ma lab, your responsibilities will include planning and conducting experiments, analyzing data, and publishing results. You'll also assist in mentoring lab personnel, reading and evaluating literature related to Alzheimer's disease, and utilizing advanced neuroscience tools to investigate neuron-glia interactions.

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What qualifications are needed for the Postdoctoral Research Fellow position at the Ma lab?

To qualify for the Postdoctoral Research Fellow position at the Ma lab, candidates should hold a Doctoral or Terminal Degree in neuroscience, neurobiology, or a related field. Experience in in vivo electrophysiology, optogenetics, and behavioral testing is highly advantageous and enhances your application.

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What benefits can I expect as a Postdoctoral Research Fellow at UTHealth Houston?

UTHealth Houston offers an excellent total rewards package for Postdoctoral Research Fellows. This includes 100% paid medical premiums, generous paid time off equating to approximately 37-38 days per year, and additional perks like free legal and mental health counseling, gym discounts, and resources for child and elder care.

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What kind of research will I be involved in as a Postdoctoral Research Fellow in Neurobiology and Anatomy?

In this position, you will be deeply engaged in research focused on understanding neuron-glia interactions in the context of Alzheimer's disease. You'll utilize innovative methodologies such as multi-photon imaging and machine learning to explore how microglia and astrocytes influence neuronal activity in mouse models.

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What opportunities for professional growth exist for a Postdoctoral Research Fellow at the Ma lab?

A Postdoctoral Research Fellow at the Ma lab will gain invaluable experience in advanced systems neuroscience. You'll have opportunities to develop independent research skills, collaborate with other researchers, and contribute to significant publications, all of which help advance your scientific career.

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Common Interview Questions for Postdoctoral Research Fellow - Neurobiology and Anatomy
Can you describe your experience with in vivo electrophysiology and its relevance to the research at the Ma lab?

When answering this question, provide details about your hands-on experiences, mentioning specific techniques and tools you've used. Relate your expertise to the Ma lab's focus on neuron-glia interactions and discuss how your background prepares you to contribute to their research goals.

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What techniques are you familiar with that could be beneficial for studying Alzheimer’s disease?

Share a list of techniques you’ve utilized in the past, such as multi-photon imaging or optogenetics. Explain how they contribute to a better understanding of Alzheimer's disease mechanisms, emphasizing your readiness to apply these in the Ma lab's research.

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How do you approach mentoring undergraduate or graduate students in a research setting?

Discuss your mentoring philosophy and provide examples of how you’ve guided students in past roles. Highlight your communication skills and how you encourage independent thinking, which aligns with the collaborative environment at the Ma lab.

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What role do you think microglia play in neuronal activity modulation?

This question allows you to showcase your understanding of neurobiology. Discuss the current findings regarding microglial functions and how these insights may influence therapeutic approaches for Alzheimer’s disease, connecting it to the lab’s research emphasis.

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Describe a research challenge you faced and how you overcame it.

Reflect on a specific instance where you encountered obstacles in your research. Discuss your problem-solving skills and the strategies you used to navigate through the challenge, demonstrating resilience and analytical thinking crucial for the Ma lab.

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What do you believe are the key factors for maintaining a productive lab environment?

Address the importance of collaboration, open communication, and mutual respect among lab members. Emphasize how these factors lead to successful research outcomes while fitting into the positive culture of the Ma lab.

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How would you communicate your research findings to a broader audience?

Provide examples of how you've previously presented your research to non-specialists, whether through public talks, blog posts, or social media. Highlight your ability to simplify complex topics, a valuable skill for the Ma lab’s outreach efforts.

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Why do you want to work at the Ma lab specifically?

Articulate your excitement about the lab’s focus on Alzheimer’s disease and neuron-glia research. Mention how their innovative methodologies resonate with your interests and how you can contribute to their impactful research agenda.

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What are your long-term career goals within the field of neuroscience?

Outline your aspirations, whether they involve continuing research, academia, or industry applications. Show how the experience at the Ma lab aligns with these goals, emphasizing your commitment to advancing neuroscience.

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How do you stay current with developments in neurobiology?

Discuss your strategies for keeping up-to-date, such as attending conferences, reading relevant journals, or participating in online courses. Highlight how continuous learning is integral to your professional growth and research contributions.

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As a comprehensive health science university, the mission of The University of Texas Health Science Center at Houston is to educate health science professionals, discover and translate advances in the biomedical and social sciences, and model the ...

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Full-time, on-site
DATE POSTED
December 23, 2024

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