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Research Associate II – In Vivo Pharmacology - Temporary

Our mission is to develop therapies that empower the immune system to combat neurodegeneration and our team is focused on developing treatments for some of the most challenging diseases facing our society. By harnessing advancements in genetics, immunology and neuroscience, we are pioneering the development of potential therapies to counteract the devastating progression of neurodegeneration. We are supported in this mission by experienced and accomplished scientists and clinicians, a novel portfolio of programs, leading healthcare investors, and pharma company partners, who share in our commitment to bettering the lives of patients and realizing a world where we make brain disorders history.


Research Associate II – In Vivo Pharmacology will be responsible for conducting in vivo studies to evaluate potential therapeutics for neurodegenerative diseases. This role involves handling and dosing rodents, collecting samples for downstream biochemical assessments, assisting in animal disease model development, and maintaining accurate records to support PK/PD, efficacy, safety, POC, MOA in vivo studies.


Key Responsibilities
  • Perform in vivo pharmacology studies in rodent models of neurodegenerative diseases, including dosing (IV, IP, SC, PO, ICV) and tissue collection.
  • Collect and process biological samples (blood, CSF, brain, and other organs) for downstream analysis.
  • Assist in the development and optimization of disease models, including Parkinson’s and Alzheimer’s disease, POC, MOA models.
  • Maintain accurate records of experiments, protocols, and data in electronic lab notebooks (ELN).
  • Collaborate daily with cross-functional teams, including Biology, ADPE, and Preclinical groups.
  • Ensure compliance with IACUC protocols and maintain high standards of animal welfare.


Qualifications
  • BS/MS in Neuroscience, Immunology, Biology, or a related field with 2+ years of in vivo research experience (industry experience preferred).
  • Hands-on experience with rodent handling, dosing techniques, in-life and terminal blood collection, and necropsy.
  • Familiarity with lymph node harvesting and CSF collection is a plus.
  • Familiarity with stereotaxic surgery and neuroanatomy is a plus.
  • Proficient in Word, Excel, PowerPoint, and GraphPad Prism.
  • Excellent organizational and communication skills.
  • Strong attention to detail.
  • Highly adaptable and capable of adjusting to shifting priorities.
  • Able to work in a fast-paced and highly collaborative environment.


$40 - $50 an hour
Hourly ranges will be determined by the candidate’s level, qualifications, skill set, and experience.

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At Alector, our vision is bold, people are our priority, and our values are at the core of everything we do. Our dynamic and flexible environment encourages our teams to experiment, take ownership of decisions, and question convention to solve complex problems. We value shared wins, perseverance, and a growth mindset, which drives us forward, together.  


Among the things you'll discover at Alector from your very first day are our committed and driven colleagues, a bold company vision, and new, modern offices designed to inspire innovation and collaboration in South San Francisco, right at the heart of Biotech Bay. Our benefits are thoughtfully designed around Alectorians and their loved ones and include flexible hybrid work options, competitive compensation, and comprehensive and unique benefits that enhance your health and well-being. Come join us! 

 

We believe that hard-working teams include people from a wide variety of backgrounds and experiences who can challenge each other’s assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.  


We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, perform essential job functions, and receive other benefits and privileges of employment. Please contact us to request accommodation. 


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$104000K

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What You Should Know About Research Associate II – In Vivo Pharmacology - Temporary, Alector

If you're passionate about making a difference in the field of neuroscience, Alector might just have the perfect role for you as a Research Associate II – In Vivo Pharmacology. Located in the vibrant South San Francisco, CA, our mission revolves around empowering the immune system to tackle neurodegenerative diseases. As a Research Associate II, you’ll dive into exciting in vivo studies using rodent models to evaluate innovative therapeutic candidates. Your tasks will include dosing rodents, collecting biological samples for further biochemical analysis, and helping develop animal disease models, such as those for Parkinson's and Alzheimer's. We celebrate a collaborative culture where you’ll engage with cross-functional teams, contributing to groundbreaking research while adhering to high standards of animal welfare. This is a dynamic environment that encourages growth and creative problem-solving. We value diversity and inclusivity, ensuring that all voices are heard and respected. With competitive pay ranging from $40 to $50 per hour based on your skills and experience, Alector prioritizes the health and well-being of our team. Join us and be part of a mission that aims to revolutionize the treatment of brain disorders, enhancing the lives of patients worldwide.

Frequently Asked Questions (FAQs) for Research Associate II – In Vivo Pharmacology - Temporary Role at Alector
What are the primary responsibilities of a Research Associate II – In Vivo Pharmacology at Alector?

As a Research Associate II – In Vivo Pharmacology at Alector, you'll be focused on conducting in vivo pharmacology studies using rodent models. This includes tasks such as dosing using various methods, collecting and processing biological samples, assisting in the development of disease models for conditions like Alzheimer's and Parkinson's, and maintaining detailed experimental records in electronic lab notebooks.

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What qualifications are needed to apply for the Research Associate II – In Vivo Pharmacology position at Alector?

Candidates interested in the Research Associate II – In Vivo Pharmacology position at Alector should have at least a BS or MS in Neuroscience, Immunology, Biology, or a related field, along with a minimum of 2 years of in vivo research experience. Experience with rodent handling and techniques such as blood collection and dosing is highly preferred.

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How does Alector support its employees in the Research Associate II – In Vivo Pharmacology role?

Alector supports its Research Associate II – In Vivo Pharmacology team members through a flexible and dynamic work environment, offering opportunities for professional growth and development. We prioritize employee well-being with competitive compensation packages and a range of benefits tailored to enhance the health and happiness of our team.

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What is the work culture like at Alector for a Research Associate II – In Vivo Pharmacology?

The work culture at Alector is collaborative, innovative, and driven by a commitment to diversity and inclusivity. As a Research Associate II – In Vivo Pharmacology, you can expect to work alongside passionate colleagues and engage in shared victories, all while solving complex challenges in the realm of neurodegenerative diseases.

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What career development opportunities are available for Research Associates at Alector?

At Alector, Research Associates like the Research Associate II – In Vivo Pharmacology have access to numerous career development opportunities. We encourage experimentation and ownership of decisions, allowing team members to challenge themselves and grow professionally while contributing to impactful research in neurodegeneration.

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Common Interview Questions for Research Associate II – In Vivo Pharmacology - Temporary
Can you describe your experience with in vivo pharmacology studies?

When answering this question, share specific details about your past experience with in vivo studies, particularly how you've handled rodents, performed dosing, and collected samples. Highlight any successful projects or challenges you've overcome to showcase your qualifications effectively.

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What models of neurodegenerative diseases have you worked with?

Discuss the specific animal models you’ve utilized in your research, focusing on how they relate to neurodegenerative diseases like Alzheimer's and Parkinson's. Mention any unique methodologies you implemented to enhance the study's efficacy and results.

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How do you ensure compliance with IACUC protocols?

In your response, outline your understanding of IACUC protocols and share specific procedures or practices you've put in place to ensure compliance in your previous roles. This demonstrates your commitment to ethical research and animal welfare.

Join Rise to see the full answer
Describe your experience with data management and documentation in research.

Emphasize your familiarity with electronic lab notebooks (ELNs) and how you maintain accurate documentation of your experiments. Provide examples of how this skill has impacted your work, particularly in terms of data integrity and collaboration with teams.

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How do you handle shifting priorities in a fast-paced research environment?

Share strategies you use to adapt to changing circumstances and priorities, such as time management techniques and collaborative efforts with your team. Highlight an example where you successfully managed competing tasks while maintaining productivity.

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What techniques are you proficient in regarding rodent handling and dosing?

Discuss your proficiency with various techniques, such as intravenous, intraperitoneal, and subcutaneous dosing methods. Sharing practical examples of your hands-on experience will illustrate your qualifications in this area.

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What analytical tools are you familiar with, and how have you used them in your research?

Mention specific software or tools, such as GraphPad Prism, that you have effectively utilized in your research. Provide insights into how you've applied these tools in analyzing biological data, preparing reports, or presenting findings.

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Can you tell us about a challenging project you worked on and how you overcame obstacles?

Select a relevant project and explain the challenges faced, the solutions you implemented, and the outcome. This showcases your problem-solving skills and resilience in research.

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How do you maintain attention to detail in your experiments?

Explain your techniques for ensuring a high level of accuracy and detail in your work, such as organizing your workspace, using checklists, or consistently reviewing protocols. This highlights your commitment to quality research.

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Why do you want to work at Alector as a Research Associate II – In Vivo Pharmacology?

Reflect on Alector’s mission and how it aligns with your values, experience, and career goals. Emphasizing your passion for neuroscience and dedication to advancing treatments for neurodegenerative diseases will demonstrate your enthusiasm for the role.

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The burden of neurodegeneration is unprecedented.Our goal is a cure. Period.At Alector, we do not view diseases of aging as immutable facts.We are on a mission to slow down their progression and prevent their occurrence.

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Temporary, on-site
DATE POSTED
April 3, 2025

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