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Senior Scientist I - Chemistry

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on XFacebookInstagramYouTubeLinkedIn and Tik Tok.

Job Description

The AbbVie Process Chemistry Chromatographic Separations Lab is actively seeking a Sr. Scientist I with experience in analytical and preparative chromatographic method development. Our team collaborates with colleagues across multiple disciplines, offering expertise in preparative chromatography to support a broad range of AbbVie R&D programs. We maintain and utilize specialized equipment for a variety separation tasks, including the purification of peptides, ADC drug-linkers, and chiral compounds, as well as the isolation of low-level small molecule API impurities. Additionally, the team is responsible for pilot-scale preparative purification, developing scalable purification processes, and overseeing their implementation under cGMP guidelines at AbbVie's North Chicago Chemical Pilot Plant. This role will contribute to the development of novel/advanced separations technologies and broader efforts to develop new process technologies for advancing the AbbVie pipeline, including the application of machine learning strategies.

We are looking for a highly motivated scientist capable of conceiving, implementing, and executing novel research and development projects. Ideal candidates will have hands-on experience developing chromatographic methods and troubleshooting complex separation challenges. Experience working with peptides is highly desirable, though not strictly required for application.

Key Responsibilities:

  • Develop and execute purification processes to support the clinical development of potential therapies, including small molecules, antibody drug conjugates, and peptides.
  • Routinely demonstrate scientific initiative and creativity in research and development activities to resolve key project hurdles.
  • Build strong relationships with peers and cross-functional partners to enhance performance.
  • Operate with autonomy and maintain a high level of productivity in laboratory research and method development, with minimal supervision.
  • Foster a learning environment, welcome diverse ideas, and encourage experimentation for improvement.
  • Adhere to corporate standards for conduct, safety, quality, and proper handling of materials.

Qualifications

Qualifications

  • Bachelor’s, Master’s, or PhD Degree in chemistry or chemical engineering with typically 10+ (BS), 8+ (MS) or 0+ (PhD) years of experience.
  • Strong technical background in Separations Science. Capable of independently developing and troubleshooting chromatographic methods.
  • A broad range of functional expertise in modern analytical analysis techniques with an emphasis on chromatography, compound purification, spectral analysis and interpretation.
  • An ability to search chemical literature and evaluate potential solutions to research problems.
  • High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​​

​​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​​

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​​

  • This job is eligible to participate in our short-term incentive programs. ​​

​​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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Average salary estimate

$100000 / YEARLY (est.)
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$80000K
$120000K

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What You Should Know About Senior Scientist I - Chemistry, AbbVie

Join AbbVie as a Senior Scientist I - Chemistry, where your expertise in analytical and preparative chromatographic method development will be crucial in shaping innovative medical solutions. Based in North Chicago, IL, you’ll collaborate with a dynamic team, contributing to AbbVie’s mission of addressing serious health issues through groundbreaking therapies in areas like immunology, oncology, and neuroscience. Your role will involve developing purification processes for crucial components like small molecules and antibody-drug conjugates, all while adhering to cGMP guidelines in our state-of-the-art Chemical Pilot Plant. We are looking for an innovative individual who is not only skilled in chromatography but also possesses a strong initiative in research and development. With a focus on fostering collaborative relationships across multidisciplinary teams, you'll have the autonomy to drive your projects while promoting a learning culture. If you have a passion for science and a commitment to making a meaningful impact in health care, this position at AbbVie could be the perfect next step in your career.

Frequently Asked Questions (FAQs) for Senior Scientist I - Chemistry Role at AbbVie
What are the main responsibilities of the Senior Scientist I - Chemistry at AbbVie?

As a Senior Scientist I - Chemistry at AbbVie, you'll take on key responsibilities such as developing and executing chromatographic purification processes, especially for small molecules and antibody-drug conjugates. Your role involves using advanced techniques in analytical and preparative chromatography, solving complex research challenges, and ensuring compliance with cGMP standards. You will also foster relationships with cross-functional teams to enhance collaboration and output.

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What qualifications do I need to apply for the Senior Scientist I - Chemistry position at AbbVie?

To apply for the Senior Scientist I - Chemistry position at AbbVie, candidates should have a Bachelor’s, Master’s, or PhD in chemistry or chemical engineering with relevant experience—typically 10+ years for a BS, 8+ years for a MS, or fresh to 3 years for a PhD. A strong technical background in Separations Science and the ability to independently develop and troubleshoot chromatographic methods are essential. Ideal candidates will also possess excellent communication skills to work effectively with interdisciplinary teams.

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What type of projects will I work on as a Senior Scientist I - Chemistry at AbbVie?

In the role of Senior Scientist I - Chemistry at AbbVie, you will work on a variety of critical projects focused on the purification of peptides, ADC drug-linkers, and chiral compounds. You'll also be involved in pilot-scale preparative purification efforts, optimizing scalable purification processes, and exploring innovative separations technologies that advance AbbVie’s drug pipeline.

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What skills are important for the Senior Scientist I - Chemistry position at AbbVie?

Essential skills for a Senior Scientist I - Chemistry at AbbVie include a strong foundation in chromatography and analytical techniques, proficiency in method development, and problem-solving capabilities for complex separation challenges. Candidates should also demonstrate creativity in research, the ability to work independently, and strong collaboration skills to engage with a diverse scientific community.

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How does AbbVie support professional development for Senior Scientist I - Chemistry?

AbbVie is committed to fostering a culture of learning and innovation, particularly for positions like Senior Scientist I - Chemistry. Employees are encouraged to engage in continuous professional development through training, collaborative projects, and access to the latest scientific resources. The company values initiative and creativity, promoting an environment where diverse ideas can flourish, ultimately contributing to both personal growth and organizational success.

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Common Interview Questions for Senior Scientist I - Chemistry
Can you describe your experience with chromatographic method development?

When asked this question, highlight specific projects where you developed chromatographic methods, detailing the techniques you used and the complexities you overcame. Mention any relevant software or technologies that support your work in chromatography to showcase your expertise.

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What strategies do you employ to troubleshoot complex separation challenges?

Focus on your systematic approach to troubleshooting. Discuss how you analyze the problem, consider different variables in the chromatography process, and incorporate literature research or peer consultations to devise solutions.

Join Rise to see the full answer
How do you ensure compliance with cGMP guidelines in your laboratory work?

Provide examples of how you have adhered to cGMP in previous roles. Discuss your understanding of quality control measures and your commitment to maintaining safety and regulatory standards throughout your research and development activities.

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What motivates you to work in the field of chemistry?

This is a chance to share your passion for chemistry. Discuss your interests, perhaps highlighting a specific project or technology that sparked your enthusiasm, and how you see yourself contributing to advancements in the medical field through your work.

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Can you describe a time when you had to work with a cross-functional team? What was your role?

Choose a collaborative project example and explain your specific contributions, emphasizing your interpersonal skills and the importance of effective communication in achieving project goals. Highlight how working with others enhanced the outcome.

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How do you stay current with advancements in analytical and preparative chemistry?

Discuss the journals, workshops, or conferences you follow to maintain your industry knowledge. Mention any specific areas of new technology or methodologies that excite you, illustrating your commitment to continuous learning.

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What challenges do you foresee in advancing chromatographic techniques in drug development?

Reflect on potential industry challenges such as regulatory changes, technological advancements, or the need for faster processing times. Offer your perspective on how you would address these challenges creatively and effectively.

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Describe your experience with machine learning strategies in chemical processes.

If applicable, discuss how you've integrated machine learning into your research. If not, express your interest in learning more about it and share any relevant training you've sought out.

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How do you handle a laboratory project that does not go as planned?

Discuss your approach to setbacks in research. Highlight your analytical skills and willingness to adapt, emphasizing how you analyze errors to refine methods and improve future experiments.

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What do you believe makes you a good fit for the Senior Scientist I - Chemistry position at AbbVie?

Present compelling reasons for your suitability, aligning your technical skills, experiences, and values with AbbVie's mission. Share examples that demonstrate your collaborative spirit, innovative thinking, and commitment to advancing healthcare.

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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: i...

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April 5, 2025

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