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Scientist, Multispecifics Engineering

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on XFacebookInstagramYouTubeLinkedIn and Tik Tok.

Job Description

Biologics Discovery Sciences at AbbVie is seeking a highly motivated research scientist to join a dynamic team supporting biologics drug discovery and multispecifics engineering. This position will impact projects through the discovery and engineering of biopharmaceutical products. The ideal candidate should have strong experience with antibody and multispecifics production, a variety of molecular cloning techniques as they relate to multispecifics biologics assembly, and knowledge of antibody fragments and mimetics. Other desirable skills include experience with antibody engineering, protein purification expertise, and familiarity with sequence analysis tools. The applicant should be able to analyze, document, and report data. They should possess excellent communication skills and be comfortable presenting in group settings.

Qualifications

Qualifications:

  • BS or MS in biology or related field with typically 5-7+ years (BS), or 2-5+ years (MS) of pharmaceutical and/or relevant experience
  • Experience with protein, biologics, fragments, and multi-specifics purification
  • Experience with bacterial and mammalian cell culture
  • Experience with in vitro analytical techniques for protein characterization (e.g. SEC, MS, DSF)
  • Strong molecular biology skills (e.g. molecular cloning)
  • Familiarity with sequence analysis tools (Vector NTI, Geneious, Genedata)
  • Understanding of protein structure and function
  • Excellent oral and written communication skills
  • Excellent organization skills and the ability to execute on multiple projects simultaneously
  • Team player with the ability to operate in a fast-paced multi-disciplinary environment
  • Adapt to rapid changes in project priorities and timelines
  • Competency with software programs, including MS Excel, Powerpoint, Word

Preferred:

  • Experience with antibody engineering, design, and optimization (e.g., humanization, Fc optimization, building multi-specifics)
  • Hands-on experience with ELISA, FACS
  • Hands-on experience with SEC, HIC, IEX purification of complex biologics utilizing AKTAs
  • Utilization of automation (e.g. Hamilton, AssayMap, Kingfisher) equipment in Biologics discovery processes
  • Proficiency with mass spectrometry deconvolution and interpretation for complex biologics
  • Proficiency with the software programs Geneious, Genedata, PMI, Bioconfirm, Unicorn
  • Experience training junior scientists

Key AbbVie Competencies:

  • Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.
  • Learns fast, grasps the “essence” and can change the course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Position will be hired based on level of experience- Scientist I or Scientist II

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

  • This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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Average salary estimate

$100000 / YEARLY (est.)
min
max
$80000K
$120000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

What You Should Know About Scientist, Multispecifics Engineering, AbbVie

At AbbVie, we're on the hunt for a passionate Scientist in Multispecifics Engineering to become a part of our vibrant team in Worcester, MA. This role is pivotal in shaping the future of biologics drug discovery through innovative research and engineering. As a Scientist, you'll dive deep into the world of biopharmaceutical products, leveraging your expertise in antibody production and multispecifics to drive impactful projects forward. If you're someone who thrives in a collaborative environment and has hands-on experience with molecular cloning techniques, protein purification, and antibody engineering, we would love to hear from you. Your daily responsibilities will include analyzing and documenting experimental data, using in vitro analytical methods for protein characterization, and presenting findings to your team. Your excellent communication and organizational skills will be key as you balance multiple projects in our fast-paced setting. This opportunity is more than just a job; it's a chance to make a real difference in the healthcare landscape while working alongside some of the brightest minds in the industry. If you're ready to embrace the challenges and excitement of multispecifics biologics engineering, apply today and join us in our mission to transform lives through science.

Frequently Asked Questions (FAQs) for Scientist, Multispecifics Engineering Role at AbbVie
What are the main responsibilities of the Scientist position at AbbVie?

As a Scientist in Multispecifics Engineering at AbbVie, you will be responsible for conducting research that supports biologics drug discovery. This includes the production and engineering of biopharmaceutical products, utilizing molecular cloning techniques, and employing various analytical methods to characterize proteins. You will also be tasked with documenting and reporting findings, collaborating with a dynamic team to ensure project progress, and communicating results effectively in group settings.

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What qualifications are required for the Scientist role at AbbVie?

To qualify for the Scientist position at AbbVie, you should have a BS or MS in biology or a related field, with several years of relevant experience in pharmaceuticals. Essential skills include strong molecular biology capabilities, experience in protein purification, and familiarity with bacterial and mammalian cell cultures. Additionally, knowledge of in vitro techniques for protein characterization and proficiency with software tools for sequence analysis are highly desirable.

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What kind of work environment can a Scientist expect at AbbVie?

At AbbVie, a Scientist in Multispecifics Engineering will work in a collaborative and fast-paced environment. You will be part of a multi-disciplinary team that emphasizes innovation, learning, and adapting quickly to changing project priorities. The company values a culture of open ideas and experimentation, where building strong relationships with peers and cross-functional partners is essential for achieving higher performance.

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What are the preferred skills for a Scientist at AbbVie?

While a strong foundational knowledge is crucial, preferred skills for a Scientist in Multispecifics Engineering at AbbVie include hands-on experience in antibody engineering, ELISA, and purification of complex biologics using advanced techniques like SEC and HIC. Familiarity with automation equipment and software tools for data analysis and interpretation, such as Geneious, are also advantageous to excel in this role.

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How does AbbVie support professional development for Scientists?

AbbVie is committed to the professional growth of its employees by fostering an environment that encourages learning and innovation. As a Scientist, you will have access to various resources for training and development, opportunities for collaboration with experienced colleagues, and the chance to get involved in knowledge-sharing activities. AbbVie values mentorship and encourages junior scientists to learn from their peers.

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Common Interview Questions for Scientist, Multispecifics Engineering
Can you explain your experience with protein purification techniques relevant to this Scientist role?

In preparing for this question, focus on detailing specific purification methods you've worked with, such as SEC, HIC, or IEX. Discuss the context in which you applied these techniques, the challenges faced, and the results of your purifications. Highlight your hands-on experience and any relevant software tools you used, linking it back to how it benefits the role at AbbVie.

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What molecular cloning techniques are you proficient in?

When answering, mention the specific molecular cloning methods you have utilized, such as restriction enzyme cloning, Gibson assembly, or CRISPR. Provide examples of projects or experiments where these techniques played a crucial role. This demonstrates your technical skills and how they align with AbbVie’s focus on multispecifics engineering.

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How do you approach data analysis and documentation in scientific research?

Explain your systematic approach to analyzing experimental data, including any software or tools you utilize for data interpretation. Describe the importance of thorough documentation and how it impacts project continuity. Emphasize your detail-oriented nature and how you use your findings to guide future research directions.

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Describe a time when you had to present research findings to a group. How did you prepare?

In your answer, highlight your preparation strategies, such as organizing data clearly, anticipating questions, and creating effective visual aids. Discuss the importance of tailoring your presentation to your audience and how this experience improved your communication skills, reinforcing your qualifications for collaboration at AbbVie.

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What challenges have you faced in antibody engineering, and how did you overcome them?

Reflect on specific challenges, such as difficulties in optimizing antibody fragments or issues encountered during humanization processes. Discuss the strategies you implemented to overcome these challenges, including team collaboration, troubleshooting methods, and innovative approaches to problem-solving relevant to the responsibilities at AbbVie.

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How do you prioritize your projects in a fast-paced environment?

It's important to demonstrate your organizational skills and adaptability. Share your strategies for prioritizing tasks, such as assessing project urgency and importance, using project management tools, and maintaining constant communication with your team. This showcases your ability to thrive in AbbVie’s dynamic work culture.

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What do you know about AbbVie’s mission and product areas?

Research AbbVie’s therapeutic areas, such as immunology, oncology, and neuroscience. When asked this question, convey your understanding of their mission to transform lives through innovative medicine. This shows your genuine interest in contributing to their goals through your role as a Scientist.

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How do you stay current with advancements in biotech and biologics?

Demonstrate your commitment to continuous learning by mentioning specific journals, conferences, webinars, or online courses you follow. Highlight how staying updated on industry trends and advancements is essential for contributing to innovative projects at AbbVie.

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What experience do you have training or mentoring junior scientists?

If applicable, provide examples of your mentoring experience, focusing on how you’ve supported junior scientists in their development. Discuss the skills you helped them with, and express your belief in the value of mentorship in fostering a productive and collaborative lab environment at AbbVie.

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How do you handle constructive criticism in a scientific setting?

Explain your view of constructive criticism as an opportunity for growth. Provide an example of how you applied feedback to improve your work or processes. This answer will highlight your willingness to learn and adapt, which aligns well with AbbVie’s values of innovation and continuous improvement.

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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: i...

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DATE POSTED
December 15, 2024

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