Senior Associate Scientist Immunology

Working with UsChallenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.Bristol-Myers Squibb is looking for Senior Associate Scientist to join the Discovery Biology Immunology team located in Lawrenceville, NJ. The position will utilize cell biological, biochemical and immunological systems and methods to identify and validate novel targets as well as to elucidate modes of actions of novel therapeutic agents in immune-mediated and inflammatory diseases. Broad expertise in cellular biology is required with preference given to candidates with demonstrated experience in primary human and murine immune cell systems. Experience in primary human and mouse epithelial cell and/or stromal cell assays is a plus . The successful candidate will have excellent oral and written communication skills, able to work well independently as well as collaboratively across other functional groups within the Discovery Research organization. The position is a hands-on, laboratory-based role. The candidate is expected to be able to plan, design, develop new assay systems, and execute projects according to plans and protocols with appropriate supervision. Meticulous record keeping, and excellent understanding in cellular immunology and related experimental systems are must-have requirements. Experience in drug discovery is desired.QualificationsEducation:BS with 4+ years of academic or industry experience or MS degree with 2+ years of academic or industry experienceRequired Experience and Skills:• In vitro and/or ex vivo skills required with a focus on immune-mediated and inflammatory disease setting:• Strong experience in cellular biology is required.• Expertise in primary human and mouse immune cell isolation, phenotyping, propagation and functional characterization is desired.• Hands on experience with a wide range of in-vitro molecular and cell biological and biochemical assays, including qRT-PCR, RNAseq, cellular localization of proteins (e.g. by imaging-based methods), western blotting, immunoprecipitation, Bio-assays (e.g. ELISA, Alphalisa, multiplexing) is required.• Experience in flow cytometric analysis, measurement of cell surface receptors and proteins by multicolor FACS across different platforms is strongly desired.• Must be able to work independently, to design and conduct experiments, including trouble-shooting outcomes and adaptively designing follow-on experiments with minimal supervision• Proficiency in scientific computer programs including Microsoft Excel, GraphPad, FlowJo• Excellent verbal skills, record keeping and make presentations of progress to be presented to research teams.• Possess a high level of critical thinking, high energy, independence, a strong desire to learn new areas, and the ability to work in a highly dynamic, transparent, collaborative research organizationPreferred Experience and Skills:• Experience in epithelial (e.g. organoid) and stromal cell assay experience a plus, including phenotyping and functional readouts (e.g. TEER, cell differentiation, proliferation and/or co-culture) is desired.• Experience in imaging techniques, Amnis image stream, confocal microscopy, and experience in siRNA/shRNA, CRISPR knockdown and qPCR is desired• Knowledge of the drug discovery process is desiredWhy You Should ApplyAround the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.Uniquely Interesting Work, Life-changing CareersWith a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.On-site ProtocolBMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.