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Downstream Process Scientist - job 1 of 2

Company Description

Are you looking for an exciting opportunity, a rewarding, enriching, and fulfilling career, and the opportunity to grow to greater levels of success with a company that values you? Then look no further! Join Eurofins PSS: a world class company that is growing by leaps and bounds while making a difference to humanity.

At Eurofins PSS, you will gain experience working in state-of-the-art laboratories, and be a part of a team that is dedicated to testing, development, and advancement of life-saving drug products to make the world a healthier and happier place to live in. Our people are our chemistry and we need talented people like you now more than ever.

Job Description

The candidate for this position will work as a member of a small team to perform scale-up/scale-down development of therapeutic biologics with strong emphasis on API proteins within the Large-Scale Development & Operations downstream (DSP) group in Malvern, PA. The candidate’s primary responsibilities will include a component of pilot-scale DSP operations execution, DSP data acquisition and modeling, and optimizing the process steps to be representative of the target process scale to ensure right first time technical transfers.

This will include:

  • Pilot-scale and occasional laboratory work with chromatographic purification and several types of filtration systems
  • Record and analyze data, verify data integrity and accuracy, and report/summarize findings to the project development teams
  • Design experiments to optimize DSP operations within the Large-Scale Development & Operations DSP group to ensure that they are representative of internal and external manufacturing sites
  • Draft technical documents, SOPs, and work instructions
  • Work in a team environment as well as contributing individually to meet project timelines and objectives

Qualifications

  • Minimum of BS in scientific related discipline is required.
  • Knowledge of and hands-on experience with DSP purification (chromatography, filtration) of protein therapeutics (such as antibodies) is required.
  • Experience with scale-up/down of DSP, and/or execution at pilot or manufacturing scales for biologics manufacture is preferred.
  • Exposure to analytical method development for in-process methods is preferred.
  • The candidate must be highly organized and capable of managing/pursuing multiple projects with some supervision.
  • Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is preferred.
  • Data reporting, ability to present findings to management, and experience with team-based collaborations is required.

Additional Information

  • Position is full-time, Mon-Fri 9am-5pm. Candidates currently living within a commutable distance of Malvern, PA are encouraged to apply. 

  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

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Average salary estimate

$70000 / YEARLY (est.)
min
max
$60000K
$80000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

What You Should Know About Downstream Process Scientist, Eurofins

At Eurofins PSS in Malvern, PA, we're on the lookout for a talented Downstream Process Scientist to join our dynamic team! If you're passionate about the development of life-saving drug products, this is your chance to be part of something incredible. In this role, you'll dive into the fascinating world of therapeutic biologics, focusing on the scale-up and scale-down processes for therapeutic proteins within our Large-Scale Development & Operations downstream group. Your day-to-day will involve engaging in pilot-scale DSP operations, where you'll be responsible for collecting and analyzing critical data. You'll optimize process steps to ensure smooth technical transfers, contributing to our mission of delivering quality healthcare solutions. From hands-on work with chromatographic purification techniques to drafting essential technical documents and SOPs, you'll play a pivotal role in our success. Collaboration is key here, as you'll join forces with fellow scientists to meet project objectives while managing multiple tasks efficiently. With a BS in a scientific discipline and experience in DSP purification, you're set up for success. Join us at Eurofins PSS where your work makes a real impact, and let's create a healthier future together!

Frequently Asked Questions (FAQs) for Downstream Process Scientist Role at Eurofins
What responsibilities does a Downstream Process Scientist have at Eurofins PSS?

As a Downstream Process Scientist at Eurofins PSS, your main responsibilities will include executing pilot-scale DSP operations, optimizing process steps, and analyzing data to ensure effective technical transfers. You'll engage in hands-on work with chromatography and filtration systems, draft technical documents, and contribute to team projects, ensuring you're integral in developing therapeutic biologics.

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What qualifications are needed for the Downstream Process Scientist position at Eurofins PSS?

To qualify for the Downstream Process Scientist role at Eurofins PSS, you require a minimum of a Bachelor’s degree in a scientific field. Hands-on experience with DSP purification techniques, such as chromatography and filtration, is essential. Exposure to pilot-scale operations and analytical method development is preferred for those looking to stand out.

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What can I expect from the work environment as a Downstream Process Scientist at Eurofins PSS?

At Eurofins PSS, you can expect a supportive and collaborative work environment as a Downstream Process Scientist. You will be part of a small team dedicated to life-saving drug development, allowing for close-knit collaborations and individual contributions towards common project goals. Our state-of-the-art laboratories foster innovation and accountability.

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How does Eurofins PSS support its Downstream Process Scientists’ career growth?

Eurofins PSS is committed to nurturing the career growth of Downstream Process Scientists. With comprehensive training, a focus on skill optimization, and opportunities to work on cutting-edge projects, you will continuously develop your expertise in therapeutic biologics. We prioritize employee satisfaction, offering development opportunities aligned with your career goals.

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What benefits can a Downstream Process Scientist expect working at Eurofins PSS?

As a Downstream Process Scientist at Eurofins PSS, you'll receive excellent full-time benefits including comprehensive medical, dental, and vision coverage, 401(k) with company matching, life and disability insurance, and paid vacation and holidays. We invest in our employees' well-being to encourage a healthy work-life balance.

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Common Interview Questions for Downstream Process Scientist
Can you explain your experience with downstream process purification techniques?

When answering this question, focus on the specific downstream purification techniques you've used, particularly chromatography and filtration methods. Discuss how you've applied these techniques in past roles and any challenges you encountered, along with how you overcame them. This showcases your hands-on experience and problem-solving skills.

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How do you approach optimizing downstream processing operations?

To address this question, detail your systematic approach to optimization. Discuss how you analyze data, design experiments, and use feedback loops to improve efficiencies. Mention specific examples where you achieved notable success in optimizing processes, which demonstrates your analytical insight and commitment to quality.

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What experience do you have with scale-up and scale-down processes?

Share relevant experiences from your past positions, highlighting specific projects where you conducted scale-up or scale-down processes. Provide details about your role in these projects, such as the challenges you faced and how your contributions led to successful outcomes. This indicates your practical understanding of process dynamics.

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Describe a time when you encountered data integrity issues. How did you handle it?

Discuss a specific instance where you identified data integrity issues in your work. Explain your process of addressing the problem, including how you verified data, implemented solutions, and improved data management practices to prevent future occurrences. This shows your attention to detail and commitment to quality assurance.

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What role do you think communication plays in teamwork for a Downstream Process Scientist?

Emphasize the importance of open and clear communication within a team. Discuss how effective communication fosters collaboration, ensures every team member is aligned on project goals, and supports a positive work environment. Provide examples from your past where strong communication led to successful project outcomes.

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How do you manage competing priorities in a fast-paced environment?

To respond to this question, describe your organizational strategies, such as project management tools or prioritization techniques. Talk about a specific example where you successfully managed multiple projects, demonstrating your ability to adapt and stay focused while meeting deadlines.

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What is your experience with technical documentation and SOP drafting?

Discuss your background in creating technical documents and standard operating procedures (SOPs). Provide examples of documents you’ve drafted, detailing how you ensure their clarity, accuracy, and compliance with industry standards. This conveys your thoroughness and understanding of regulatory requirements.

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How do you ensure the accuracy of your experimental data?

Illustrate your methods for ensuring data accuracy, such as double-checking results, maintaining rigorous documentation, and using appropriate controls in experiments. Sharing an anecdote about a challenging experiment where data integrity was crucial can add depth to your response.

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Can you describe a successful collaboration in your previous roles?

Choose a specific example where you collaborated successfully with others to achieve a project goal. Highlight your role in the collaboration, the skills you utilized, and the outcome. This demonstrates your teamwork abilities and how you can contribute positively to the Eurofins PSS culture.

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What motivates you to work in the field of therapeutic biologics?

Share your passion for therapeutic biologics, focusing on why you find this field impactful. Describe your commitment to improving patient outcomes and your eagerness to contribute to innovative solutions in healthcare. This personal insight can create a connection with your interviewers.

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DATE POSTED
April 15, 2025

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