Intern - Clinical Pharmacology - job 1 of 2

Company Summary:

Kriya is a next-generation gene therapy company focused on expanding the field to new frontiers. We have built a fully integrated, technology-enabled platform for rational vector design, analytical characterization, and scalable manufacturing to design and develop gene therapies for diseases with well-understood underlying biology. We believe that rationally engineered gene therapies can transform the treatment of a broad universe of diseases – and we are prepared to lead this revolution in medicine.

Our team is made up of leading scientific experts who are passionate about improving patients’ lives and easing the burden of these life-changing disorders for patients. We are looking for teammates with the ambition, creativity, and energy to help us build a unique organization.

If you are looking to be a part of a company with an entrepreneurial culture, a bold vision, and a meaningful purpose, Kriya is the company for you.

Position Summary:

We are seeking an independent and highly organized summer intern to join the Clinical Pharmacology team at Kriya. The intern will contribute to the development of Quantitative Systems Pharmacology model of adeno-associated virus (AAV) based gene therapy for first-in-human dose prediction. This internship is an excellent opportunity to gain direct experience working in an industry setting across functional areas of drug development (Regulatory, CMC, Quality, Clinical, Preclinical).

Primary Responsibilities:

The overall objective of the intern is to use quantitative modeling approaches to characterize/understand AAV kinetics and identify intrinsic factors that my influence transgene product expression:

• Perform statistical analysis and interpretation of literature and in-house proprietary data
• Develop mathematical models (e.g. PK/PD, Population PK, etc.)
• Present to broader team at the conclusion of assignment
• Conduct multivariate analysis to interrogate complex biological problems
• Create models, analyses and reports using R, NONMEM, and/or Matlab

Required Qualifications:

• Currently enrolled in university, pursuing a PhD in Pharmacokinetics, Pharmaceutical Science, Pharmacometrics, Pharmacology, or related mathematical/statistical field
• Previous experience and interest in applying quantitative/mechanistic modeling to describe biological/pharmacological processes
• Strong analytical, problem-solving, and oral and written communication skills
• Must be enrolled in university during the internship period

Working Conditions:

• Work is normally performed in a typical office work environment
• This is a hybrid role consisting of 2 days per week, in office. (remote only possible).

Kriya is an equal opportunity employer.

We celebrate diversity and are committed to creating an inclusive environment for all employees.

All job requirements in the job description provided indicate the minimum level of knowledge, skills, and/or abilities deemed necessary to perform the job competently. Job descriptions are an overview of the duties, responsibilities, and requirements of the position. Employees may be required to perform other job-related assignments as requested.