Associate Director/Director, Toxicology

To be considered for the Associate Director/Director, Toxicology role at Korro, candidates must hold a DVM, Ph.D., or an equivalent degree in Toxicology or a related field. Additionally, DABT/DACVP certification is preferred. Candidates should also have 7-10 years of experience as a regulatory toxicologist in the pharmaceutical or biotechnology industry. A proven track record of leading toxicology programs through various drug development phases is crucial.

The primary responsibilities of the Associate Director/Director, Toxicology at Korro include the design and oversight of IND/CTA toxicology studies, authoring nonclinical sections of regulatory submissions, and representing toxicology at cross-functional project teams. The role involves strategic input on toxicological evaluations and providing guidance on study design and data interpretation, ensuring alignment with company objectives and regulatory standards.

The Associate Director/Director, Toxicology plays a vital role in Korro's research and development goals by influencing the overall development strategy of candidate molecules. This position collaborates with various departments, ensuring that toxicology results are integrated into project timelines and strategic planning, ultimately aiding in the advancement of innovative genetic medicines.

Korro prides itself on a collaborative and inclusive work environment. As an Associate Director/Director in Toxicology, you will be working alongside a team of dedicated professionals who share a commitment to innovative science and patient health. The atmosphere is dynamic and flexible, accommodating collaboration across different time zones, which adds to the vibrant company culture.

Korro offers a competitive compensation package for the Associate Director/Director, Toxicology that includes equity-based compensation along with a comprehensive benefits package. This includes medical, dental, and vision coverage, a 401(k) retirement plan, life insurance, a dependent care flexible spending account, a health savings account, and free parking, reflecting Korro's commitment to employee well-being.

In answering this question, focus on specific examples from your past roles where you've been directly involved in GLP toxicology studies. Detail your responsibilities and highlight how your contributions impacted the overall success of drug development. Emphasize your understanding of GLP regulations and share specific metrics or outcomes that resulted from your efforts.

Use the STAR method to outline the situation, task, action, and result. Discuss a specific challenge you faced in toxicology and the steps you took to address it. Emphasize your problem-solving skills and ability to collaborate with other departments, showcasing how your actions led to a successful resolution and informed future projects.

Talk about your proactive approach to staying informed, such as subscribing to industry publications, attending conferences, participating in workshops, or being a member of professional organizations. Mention specific sources or networks that you rely on for the latest information and how you apply this knowledge in your work.

Explain your methodology for designing nonclinical safety studies, detailing how you assess the objectives, regulatory requirements, and scientific principles behind the studies. Provide an example of a study you designed and discuss the factors you considered to ensure comprehensive data collection and analysis.

Highlight your experience working with different departments such as discovery, bioanalysis, or regulatory affairs. Provide an example of a project where cross-functional collaboration was critical to achieving project goals and how you navigated any challenges that arose, underscoring your ability to communicate effectively.

Discuss the critical function that toxicology serves in ensuring the safety and efficacy of therapeutics. Emphasize how toxicological assessments inform decisions throughout the development process, influence regulatory submissions, and ultimately protect patient health, aligning with Korro's mission.

Share your strategies for time management and prioritization, such as methodologies you follow or tools you use to keep track of tasks. Discuss how you've successfully managed competing deadlines in past roles while maintaining high standards of quality in your submissions.

Emphasize your commitment to mentoring and developing your team. Highlight specific ways you have provided guidance and support to junior team members, such as training programs or collaborative projects. Showcase your belief in fostering an environment where everyone feels valued and empowered.

Explain how you simplified complex toxicological concepts and results for your audience, focusing on clarity and engagement. Talk about the tools or methods you used, such as visuals or analogies, and the resulting feedback from the presentation.

Discuss your systematic approach to maintaining compliance with GLP regulations and other industry standards. Highlight how you stay updated on any changes and how you implement best practices in your work to ensure that all studies meet the required guidelines for regulatory submissions.