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Research Associate II / Senior Research Associate, In-Vivo Pharmacology

Lycia Therapeutics, Inc. is a biotechnology company leveraging its lysosomal targeting chimera (LYTAC) platform from Founder and Chemistry Nobel Laureate 2022, Carolyn Bertozzi, to discover and develop first-in-class therapeutics that degrade extracellular and membrane-bound proteins. Lycia’s next generation degraders harness the cell’s endogenous lysosomal trafficking and degradation machinery with the potential to degrade targets previously considered to be intractable, across a spectrum of indications. After raising $105 million in capital in 2021, Lycia is advancing an internal pipeline of novel degraders and has entered a strategic collaboration with Eli Lilly to address key unmet medical needs. In May 2024, Lycia Therapeutics completed a $106.6 million series C financing to advance its pipeline of LYTAC extracellular protein degraders to the clinic. Lycia is headquartered in South San Francisco.

Visit https://lyciatx.com/ for more information.

The Role:

Lycia Therapeutics is seeking a self-motivated, organized, and technically skilled in vivo pharmacology Research Associate II or Senior Research Associate. The successful applicant will engage in innovative research in a dynamic team environment, with a focus on developing and executing in vivo studies to support target validation and drug discovery efforts. A passion for translating basic scientific insights into generation of novel therapeutics is a must.

Responsibilities:

As part of the in vivo pharmacology team, conduct and support in vivo studies to evaluate pharmacokinetics, pharmacodynamics, efficacy, mechanism of action, and/or tolerability of novel therapeutics based on the LYTAC platform.
Duties will include contribution to study design, drug administration, blood collection, IVIS imaging, surgical procedures, tissue dissection/processing, and monitoring of disease models.
Evaluate, interpret, and document scientific results and communicate findings within functional and project teams.
Collaborate with colleagues in cross-functional project teams to support drug discovery and drug development efforts for various pipeline and platform programs.

Requirements:

B.S/B.A or M.S. in cell biology, molecular biology, biochemistry, pharmaceutical sciences, immunology, or related field with + 0 to 4 years of relevant experience. Previous industry experience is preferred.
Proficiency with animal handling procedures (e.g., husbandry, dosing via multiple routes, blood collection, organ harvests, tissue processing, etc.). Substantial experience with intravenous dosing is a plus.
Willingness to learn new in vivo techniques.
Ability to work independently while contributing to an integrated team.
Must be organized and detail-oriented with meticulous record keeping.
Flexibility to contribute to multiple studies while remaining well organized.
Highly motivated team player with excellent written and oral communication skills.
Proficiency in standard software (e.g., MS office and GraphPad).

$87,000 - $115,000 a year

The expected base salary range for this role is $87,000 - 95,000 for Research Associate II and $100,000 - 115,000 for Senior Research Associate . We encourage candidates of all levels to apply as there is often flexibility on job title and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications and internal equity. Lycia offers a competitive employment package that includes an annual bonus, equity, and a generous benefits package.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status

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$101000 / YEARLY (est.)

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$87000K

$115000K

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What You Should Know About Research Associate II / Senior Research Associate, In-Vivo Pharmacology, Lycia Therapeutics

Lycia Therapeutics, Inc. is excited to announce a fantastic opportunity for a Research Associate II or Senior Research Associate in In-Vivo Pharmacology based in South San Francisco. We're a pioneering biotechnology company, leveraging revolutionary technology to develop first-in-class therapeutics that can degrade extracellular and membrane-bound proteins. If you have a knack for innovative research and a desire to translate basic scientific insights into groundbreaking therapies, this role might be your perfect match! As part of our dynamic in vivo pharmacology team, you will conduct critical studies evaluating pharmacokinetics, pharmacodynamics, efficacy, and much more. Your tasks will range from study design and drug administration to tissue processing and IVIS imaging. This is a unique opportunity to collaborate within cross-functional teams, driving our drug discovery efforts forward. We’re looking for someone with a degree in biology or a related field, with experience and proficiency in animal handling and a passion for learning new techniques. You’ll need to be detail-oriented, organized, and a superb communicator. With an expected salary range of $87,000 to $115,000 based on experience and qualifications, it's an exciting time to join us at Lycia, especially as we advance our pipeline of innovative therapies. Come be part of something special and help shape the future of medicine!

Frequently Asked Questions (FAQs) for Research Associate II / Senior Research Associate, In-Vivo Pharmacology Role at Lycia Therapeutics

What are the main responsibilities of a Research Associate II at Lycia Therapeutics?

As a Research Associate II at Lycia Therapeutics, your primary responsibilities will involve conducting and supporting in vivo studies aimed at evaluating various aspects of novel therapeutics. This includes pharmacokinetics, pharmacodynamics, efficacy, and mechanism of action. You will be involved in study design, drug administration, blood collection, IVIS imaging, and surgical procedures, all critical for advancing our drug discovery efforts.