Senior Scientist 1, In Vivo Pharmacology

As a Senior Scientist 1, In Vivo Pharmacology at Eikon Therapeutics, you'll be responsible for performing ex-vivo molecular analysis on tissues from both clinical and pre-clinical disease models. This includes supporting the in vivo characterization of novel chemical entities and engaging with clinical and animal scientist colleagues to design studies. You'll also develop and validate biomarker assays and potentially mentor junior research associates, contributing your expertise across various drug development programs.

To qualify for the Senior Scientist 1, In Vivo Pharmacology role at Eikon Therapeutics, candidates typically need either a Postdoc fellowship plus 2 years of relevant experience, a Ph.D. with a minimum of 5 years, a Master's degree with 14 years, or a Bachelor's degree with 16 years of relevant experience. Significant hands-on experience in drug discovery and molecular biology techniques, including immunoassays and PCR, is also essential.

A Senior Scientist 1 at Eikon Therapeutics should be proficient in various molecular biology techniques such as immunoassay development, real-time and conventional PCR, flow cytometry, and possibly immuno-histochemistry. Hands-on experience analyzing whole tissues, including tumor and organ samples, is crucial for successfully performing the duties of this role.

The Senior Scientist 1, In Vivo Pharmacology role at Eikon Therapeutics plays a critical part in our drug discovery efforts by providing essential insights into target engagement and bioactivity through molecular analysis of clinical and pre-clinical tissue samples. Your ability to develop and validate biomarker assays will directly impact our understanding of the efficacy of novel chemical entities, thereby driving our drug development choices and timelines.

At Eikon Therapeutics, a Senior Scientist 1, In Vivo Pharmacology can expect an exciting and fast-paced work environment. You'll be part of a highly energetic and collaborative team driven by scientific rigor. With significant interaction across various project teams, this role encourages sharing ideas and leveraging expertise in a dynamic culture, especially as we transition to our new headquarters in Millbrae, CA.

To answer this question effectively, highlight specific molecular biology techniques you have worked with, such as ELISA, PCR, and flow cytometry. Provide examples of projects where you applied these techniques, emphasizing your role and any notable outcomes.

Describe your systematic approach to data analysis, from experimental design to the interpretation of results. Discuss tools and software you use for data analysis and how you ensure accuracy through rigorous documentation and peer review.

Share a story of a project where you worked collaboratively with team members. Outline your role, the budget or timelines you adhered to, and the positive outcomes from the collaboration. Highlight communication as a key aspect of success.

Discuss your practices for maintaining meticulous lab notebooks and following protocols precisely. Explain how you handle mistakes when they occur, and emphasize the importance of validation and cross-checking your results with colleagues.

Reflect on your passion for scientific discovery and how the prospect of contributing to novel treatments for diseases drives your work. Share specific inspirations, such as past research experiences or personal connections to the field.

Illustrate your organizational skills by discussing specific strategies you use to prioritize tasks, such as time management techniques, planning tools, or collaboration with team members to align on goals.

Share your career aspirations in pharmacology, linking them to the company's goals. Highlight your desire for growth and ongoing learning, and potentially take on leadership roles as you become an expert in the field.

Explain your approach to continuous learning, such as attending conferences, following relevant journals, and networking with professionals. Emphasize the importance of knowledge sharing in advancing your career and the field.

Identify potential challenges, such as handling complex data sets or keeping up with fast-paced research timelines. Then discuss strategies you would use to tackle these challenges proactively.

Articulate your genuine interest in Eikon Therapeutics by discussing the company’s innovative approach to drug discovery, its values, and the exciting work culture. Highlight how your skills and passion align with their mission.