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Scientist II, Biologics Drug Product Development

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on XFacebookInstagramYouTubeLinkedIn and Tik Tok.

Job Description

The Biologics Drug Product Development group within AbbVie is a global organization responsible for developing and characterizing drug product formulations and manufacturing processes for biologic therapeutics (antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats) from preclinical development through clinical proof of concept.

We have an exciting opportunity for a Scientist II to join our team at our Bay Area site in South San Francisco, CA. This position requires an onsite presence and involves lab-based functions. Successful candidates will thrive in a collaborative lab environment and engage in daily cross-functional interactions with fellow scientists.

KEY RESPONSIBILITIES INCLUDE:

  • As a technical expert in drug product, develop, optimize, and innovate biologic formulations to enable clinical studies in a phase appropriate manner.
  • Design and execute experiments independently for formulation development, drug product process development, and in-use studies to ensure stability and accurate administration.
  • Analyze and interpret experimental data independently to address scientific inquiries aligned with project and management goals.
  • Develop and refine formulations, methods, and protocols to drive innovation while ensuring reliability and scalability.
  • Collaborate cross-functionally to achieve project timelines and objectives, applying a deep understanding of CMC and drug product development.
  • Manage experimental timelines effectively and adjust plans as required in consultation with project leads and stakeholders.
  • Stay well-informed with scientific literature to enhance technical expertise and apply it to assignments in drug product development.
  • Generate and document high-quality scientific data using electronic lab notebooks.
  • Present scientific plans and data effectively and document studies through comprehensive reports.
  • Contribute to the conceptualization and writing of publications, presentations, and patents.

Qualifications

  • Bachelor’s degree in Chemistry, Biochemistry, Chemical Engineering, Bioengineering, Pharmaceutical Sciences, or related field with at least 7 years of industry experience, or a Master’s degree with at least 5 years of industry experience.
  • Proven experience in biologic formulation development for both liquid and lyophilized products. Experience in platform formulation development is a plus.
  • Proficiency in biologic drug product process development, with hands-on experience with fillers, liquid handlers, and lyophilizers.
  • Expertise in analytical techniques for protein characterization and stability testing (e.g., SEC, CE-SDS, icIEF, HIAC, MFI, DLS).
  • Experience in analytical method development is preferred.
  • Strong attention to detail, organizational skills, and problem-solving capabilities.
  • Excellent communication skills, both oral and written, with a commitment to maintaining detailed lab records.
  • Eagerness to learn and apply new scientific techniques.
  • Ability to manage multiple tasks efficiently within established timelines, with strong planning and analytical skills.
  • Strong collaborative skills for working effectively within and outside the team.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • On-site opportunity located in South San Francisco office. 
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
  • This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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Average salary estimate

$135000 / YEARLY (est.)
min
max
$120000K
$150000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

What You Should Know About Scientist II, Biologics Drug Product Development, AbbVie

Are you a talented scientist looking to make a real impact in the world of biologics? AbbVie, a leading biopharmaceutical company, is excited to offer an opportunity for a Scientist II in Biologics Drug Product Development at our beautiful site in South San Francisco, CA. This role is perfect for someone who thrives in a collaborative lab environment and is passionate about developing innovative drug formulations. As a Scientist II, you'll have the chance to work on cutting-edge biologic therapeutics—including antibodies and antibody-drug conjugates—driving the development and optimization of drug product formulations. You'll independently design and execute experiments, analyze data, and contribute to project goals while staying updated with the latest scientific literature. This is more than just a job—it's a chance to be part of a dedicated team committed to improving lives through advanced therapeutic solutions. With your background in chemistry, biochemistry, or a related field and a proven track record in biologic formulation development, you will be integral in ensuring the stability and efficacy of our drug products. Join us in making a difference!

Frequently Asked Questions (FAQs) for Scientist II, Biologics Drug Product Development Role at AbbVie
What are the key responsibilities for the Scientist II position at AbbVie?

As a Scientist II in Biologics Drug Product Development at AbbVie, your key responsibilities will include developing, optimizing, and innovating biologic formulations, executing experiments independently, analyzing experimental data, collaborating with cross-functional teams, and managing timelines. You'll play a crucial role in ensuring clinical studies are conducted efficiently and effectively.

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What qualifications are needed for the Scientist II role at AbbVie?

To apply for the Scientist II position in Biologics Drug Product Development at AbbVie, you need a Bachelor’s degree in a related field along with at least 7 years of industry experience, or a Master’s degree with a minimum of 5 years of experience. Proven experience in biologics formulation development and proficiency in analytical techniques for protein characterization are essential.

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What type of work environment can a Scientist II expect at AbbVie?

A Scientist II at AbbVie can expect a collaborative lab environment where teamwork and cross-functional interactions are key. You'll be working closely with fellow scientists and stakeholders, enabling you to engage in meaningful scientific discussions and contribute to impactful projects in biologics drug product development.

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How does AbbVie support the career growth of a Scientist II?

AbbVie is committed to fostering the development of its employees. As a Scientist II, you'll have access to various learning opportunities, including workshops, mentorship from senior scientists, and the chance to publish your findings. The company encourages continuous learning and applying new scientific techniques, allowing you to advance your career in a forward-thinking environment.

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What types of biologic products will a Scientist II work on at AbbVie?

In the Scientist II role at AbbVie, you will work on a variety of biologic products, including monoclonal antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats. Your work will directly contribute to the formulation and development of these innovative therapeutics.

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Common Interview Questions for Scientist II, Biologics Drug Product Development
Can you describe your experience with biologic formulation development?

When answering this question, be specific about the types of biologics you have worked on and the methods you used for formulation development. Be prepared to discuss any challenges you faced and how you overcame them, showcasing your problem-solving skills.

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How do you prioritize tasks when managing multiple projects in the lab?

In your response, explain your organizational strategies, such as using project management tools or setting clear milestones. Highlight your ability to remain flexible and adjust your priorities based on project needs or deadlines to demonstrate your adaptability.

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What analytical techniques have you used for protein characterization?

Discuss your hands-on experience with relevant techniques like SEC, CE-SDS, or DLS. Provide examples of how you've applied these techniques to analyze protein stability or quality, emphasizing your technical knowledge and analytical skills.

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How do you ensure the reliability and scalability of drug product formulations?

Talk about the importance of planning and rigorous testing in formulation development. Mention any specific protocols you've followed to validate formulations and ensure they are scalable, highlighting your commitment to quality.

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Describe a successful collaboration experience with cross-functional teams.

Provide a specific example of how you worked with colleagues from different departments to achieve a common goal. Emphasize your communication skills and ability to integrate feedback from various stakeholders, showcasing your collaborative spirit.

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How do you stay current with scientific literature and advancements in biologics?

Illustrate your proactive approach to professional development. Discuss the journals you read, conferences you attend, or online courses you take to stay informed about the latest innovations in drug product development and biologics.

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What motivates you to work in biologics drug development?

Share what initially drew you to this field and what continues to inspire you. Focus on your passion for improving patient outcomes and the excitement of working on innovative therapeutics.

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Can you explain a time when an experiment did not go as planned?

When discussing a failed experiment, emphasize your critical thinking and problem-solving skills. Describe how you analyzed the situation, what changes you made, and how the experience contributed to your growth as a scientist.

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What steps do you take to document your lab work accurately?

Explain the specific practices you follow to ensure comprehensive and precise documentation, including the use of electronic lab notebooks, maintaining detailed records of experiments, and adhering to compliance guidelines. This demonstrates your attention to detail.

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Why do you want to work for AbbVie specifically?

Tailor your response to show that you understand AbbVie's mission and values. Discuss how you align with their commitment to innovation and improving patient lives, and express your interest in contributing to their impactful projects in biologics.

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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: i...

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Full-time, on-site
DATE POSTED
December 17, 2024

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