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Senior Research Associate - Process Development

BrainChild Bio is seeking to hire a Senior Research Associate to grow our Process Development team.  This role will support the design and execution of development studies as we scale our therapies beyond the early clinical research setting through commercialization to commercial launch.  The ideal candidate will have a background in cell selection, lentiviral transduction, and cell culture expansion.  They will be excited to assist with software-driven Design of Experiments (DOE) and scale down model studies, as well as full scale CAR-T cell production runs that will enable process optimization and understanding.  The successful candidate will be a creative problem solver that thrives while working in a fast-paced, highly collaborative environment. 


Responsibilities:
  • Design and execute experiments to support cell therapy process development including Design of Experiments (DOE) studies to efficiently optimize unit operations 
  • Document experiments in a timely and thorough manner using electronic laboratory notebooks 
  • Perform statistical data analysis using JMP software 
  • Author study reports detailing experimental work and summarizing results 
  • Present experimental findings to cross-functional teams following study completion 
  • Support planning activities prior to study execution including batch record authoring and reagent/material preparation 
  • Maintain a safe work environment in accordance with lab policies and procedures  


Qualifications:
  • BS/MS inBioengineering, Chemical Engineering, Biology, or other related discipline 
  • 2+ years of relevant lab experience.  Prior experience in cell therapy industry preferred. 
  • Proficiencywith mammalian cell culture sterile technique 
  • Proficiency with lab electronic notebook and report writing 
  • Flexibility with work schedule (i.e., occasional weekend work) 


$90,000 - $100,000 a year

Average salary estimate

$95000 / YEARLY (est.)
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$90000K
$100000K

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What You Should Know About Senior Research Associate - Process Development, BrainChild Bio

Are you passionate about advancing cutting-edge therapies? BrainChild Bio is on the lookout for a dynamic Senior Research Associate in Process Development to join our growing team in Seattle, WA. In this exciting role, you'll play a pivotal part in the design and execution of development studies that help take our transformative therapies from early clinical research to commercialization. As a Senior Research Associate, you will apply your expertise in cell selection, lentiviral transduction, and cell culture expansion to facilitate software-driven Design of Experiments (DOE) and scale down model studies. If you enjoy tackling challenges in a team environment and thrive in a fast-paced setting, this could be the perfect role for you. Your daily responsibilities will include designing and executing experiments, documenting your findings using electronic laboratory notebooks, and performing statistical data analysis with JMP software to optimize our CAR-T cell production processes. You will also be tasked with authoring detailed study reports and presenting your results to a collaborative cross-functional team. To excel in this position, you should hold a BS/MS in Bioengineering, Chemical Engineering, Biology, or a related field, along with at least 2 years of lab experience, preferably in the cell therapy industry. Proficiency in mammalian cell culture techniques and flexible work hours, including occasional weekends, is crucial. Join us at BrainChild Bio and contribute to pioneering innovations in cell therapy for a healthier future!

Frequently Asked Questions (FAQs) for Senior Research Associate - Process Development Role at BrainChild Bio
What are the main responsibilities of a Senior Research Associate - Process Development at BrainChild Bio?

As a Senior Research Associate - Process Development at BrainChild Bio, your main responsibilities will include designing and executing experiments for cell therapy process development, conducting Design of Experiments (DOE) studies, and documenting your work thoroughly using electronic laboratory notebooks. You'll also perform statistical analysis using JMP software, author study reports, and present your findings to cross-functional teams, all while maintaining a safe laboratory environment.

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What qualifications are needed to apply for the Senior Research Associate - Process Development position at BrainChild Bio?

To apply for the Senior Research Associate - Process Development role at BrainChild Bio, candidates should possess a BS/MS in Bioengineering, Chemical Engineering, Biology, or a related field. Additionally, you should have at least 2 years of relevant laboratory experience, preferably in the cell therapy industry, along with proficiency in mammalian cell culture techniques and experience with electronic lab notebooks.

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How does BrainChild Bio support the career growth of a Senior Research Associate - Process Development?

BrainChild Bio is committed to the professional development of its employees, including Senior Research Associates in Process Development. By providing opportunities for hands-on experience in cutting-edge projects, access to continuous learning resources, and participation in cross-functional meetings, team members are encouraged to grow their skills and advance their careers in the dynamic field of cell therapy.

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What tools and software will a Senior Research Associate - Process Development use at BrainChild Bio?

In the role of Senior Research Associate - Process Development at BrainChild Bio, you will utilize several tools and software programs including JMP for statistical data analysis and electronic laboratory notebooks for documenting experiments. Familiarity with Design of Experiments (DOE) software may also be beneficial as you help drive innovations in our therapies.

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What is the work environment like for a Senior Research Associate - Process Development at BrainChild Bio?

The work environment at BrainChild Bio is fast-paced, collaborative, and focused on innovation. As a Senior Research Associate - Process Development, you will work closely with a talented team that emphasizes problem-solving and collective advancement in cell therapy. A commitment to safety and adherence to lab policies is essential for maintaining a productive and supportive workplace.

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Common Interview Questions for Senior Research Associate - Process Development
Can you describe your experience with Design of Experiments (DOE) and how it applies to process development?

In your response, highlight specific experiences you've had using DOE in previous roles. Discuss how you designed experiments to optimize processes, what results you achieved, and how you collaborated with your team to analyze and interpret the data.

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What strategies do you use for maintaining accurate documentation in a laboratory setting?

Explain the importance of proper documentation in research and describe your typical approach. Mention using electronic laboratory notebooks, ensuring clarity in your notes, and reviewing documentation regularly with your team to enhance communication.

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How do you handle unexpected results in experiments?

Demonstrate your problem-solving skills by discussing a specific instance when an experiment did not go as planned. Describe how you analyzed the situation, what steps you took to uncover the issue, and how you adjusted your experimental design moving forward.

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What is your experience with cell culture techniques?

Share your background with mammalian cell culture, emphasizing your proficiency in sterile techniques and any challenges you faced in past roles. Discuss how you've worked to improve cell culture practices in your previous lab experiences.

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Can you give an example of a successful collaboration with cross-functional teams?

Illustrate your experience by sharing an example of a project where you partnered with other departments. Focus on the project objectives, your role, how you facilitated communication between teams, and the overall outcome of the collaboration.

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How do you prioritize tasks when working on multiple experiments?

Discuss your organizational strategies for managing time efficiently. Mention tools you use for tracking tasks, how you assess the urgency and importance of experiments, and how you communicate with your team to ensure alignment.

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What is your approach to data analysis when working with JMP software?

Describe your familiarity with JMP software and how you use it to analyze experimental data. Discuss any specific techniques you apply, such as regression analysis or data visualization, and how these contribute to your findings.

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Can you outline your experience with authoring study reports?

Explain the importance of clear and concise report writing in research and describe your process for documenting studies. Share examples of key elements you include in reports and how you present results to your peers or stakeholders.

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What motivates you to work in the field of cell therapy?

Express your passion for advancing healthcare through innovative therapies. You could discuss personal experiences, professional achievements, or specific aspects of the cell therapy field that inspire you to contribute your skills and knowledge.

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How do you maintain a safe laboratory environment?

Show your awareness of laboratory safety protocols by discussing specific practices you employ. Speak about regular safety checks, adherence to policies, and fostering a culture of safety among your teammates.

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MATCH
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LOCATION
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EMPLOYMENT TYPE
Full-time, on-site
DATE POSTED
December 27, 2024

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