Vice President, Medical Affairs

The Vice President of Medical Affairs at Spyre Therapeutics is responsible for leading the medical affairs team, overseeing clinical trials, ensuring regulatory compliance, and developing medical content for various stakeholders. This role involves strategic leadership to align medical strategies with the company's objectives, managing cross-functional collaboration, and maintaining relationships with key opinion leaders within the IBD space.

Candidates for the Vice President, Medical Affairs position at Spyre Therapeutics should hold a PhD, PharmD, or Medical Degree along with a minimum of 12 years of experience in medical affairs or clinical development within the pharmaceutical or biotech industry. Strong experience in IBD, inflammation, or immunology, along with demonstrated leadership and regulatory knowledge, is strongly preferred.

The Vice President of Medical Affairs plays a critical role in clinical development at Spyre Therapeutics by overseeing the design and execution of clinical studies and ensuring all information is compliant with regulatory standards. This individual collaborates with Clinical Operations and Development teams, providing medical expertise while monitoring emerging trends in the IBD market to inform decision-making.

At Spyre Therapeutics, the Vice President of Medical Affairs can expect to work in a fast-paced, dynamic remote environment, complemented by frequent in-person meetings to foster collaboration on complex issues. This role includes high levels of teamwork and a culture that encourages professional growth and innovation.

Spyre Therapeutics is committed to providing comprehensive professional development opportunities for its employees, including the Vice President of Medical Affairs. This includes mentorship, learning resources, and programs designed to enhance skill sets, along with a commitment to creating a diverse and inclusive work environment.

When asked about your experience leading medical affairs teams, be sure to highlight specific instances where you've successfully built or managed a team, your approach to leadership, and the outcomes of your efforts. Discuss the collaborations and initiatives you have driven that resulted in improved operational efficiency or better alignment with corporate objectives.

To answer how you ensure compliance with regulatory requirements, share your understanding of regulations and guidelines you’ve implemented in past roles. Provide examples of how you've monitored compliance during clinical trials, and discuss any processes or training initiatives you created to enhance awareness of regulatory obligations within your team.

Describe your approach to engaging with key opinion leaders by emphasizing relationship-building strategies. Talk about how you've established connections, maintained communication, and addressed their needs in past roles. Highlight specific instances where these relationships have led to successful collaborations or insights into market trends.

When asked about prioritizing projects, describe your method for evaluating project importance and urgency. Discuss how you balance the demands of clinical development, regulatory compliance, and team management. Providing examples of prioritization in a previous role can demonstrate your organizational skills.

For this question, explain your systematic approach to handling medical inquiries and adverse event reports. Include your methods for ensuring prompt and effective responses, the importance of documentation, and how you collaborate with the clinical and regulatory teams to maintain compliance while addressing these inquiries.

When discussing your experience with medical content development, highlight specific types of documents you have produced, such as scientific publications, presentations, or educational materials. Share examples of how you’ve tailored content for various audiences while ensuring accuracy and scientific integrity.

In your response, choose an example that showcases your problem-solving ability and strategic thinking. Clearly outline the challenge, the actions you took to address it, and the positive outcomes that resulted. This will demonstrate your capability to handle adversity in a leadership role.

Discuss the strategies you employ to stay informed about trends in the IBD market. This could involve attending conferences, reading industry publications, connecting with thought leaders, or leveraging professional networks. Explain how this knowledge has impacted your prior roles in medical affairs.

When answering this question, describe your leadership style, whether it's transformational, participative, or situational. Share how you motivate your team, facilitate collaboration, and nurture professional growth, using examples to illustrate your approach's effectiveness.

In your response, highlight your understanding of how to integrate medical strategies into broader business objectives. Discuss your experiences in aligning medical affairs with commercial and clinical developments while ensuring that the company's scientific integrity and patient outcomes remain top priorities.