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Research Assistant II

The Jalili lab is seeking a motivated research assistant II to join our innovative laboratory to carry out cutting-edge research on modeling and monitoring host immune-microbiome crosstalk in the context of infectious diseases, autoimmunity and cancer. We are a highly interdisciplinary team working at the interface of biomaterial science, immunology and microbiology. The prospective candidate will be exposed to a variety of research topics and engage in diverse experiments that utilize cellular and molecular biology, biomaterial science, immunology and microbiology techniques as well as animal models. The candidate will work under the guidance of the principal investigator and postdoctoral associates to help with 3D organoid and Organ on Chips cultures and developing immune monitoring/diagnosis devices. This position will involve cell and bacterial culturing, microfluidic device fabrication and culturing, and handling mouse models. The candidate will also assist in daily lab organization and operations.

This position is ideal for postbacs who are looking to enrich their hands-on research experience before pursuing graduate studies or transitioning into industry positions.

Applicants are expected to hold a bachelor’s degree in biomedical engineering, biology, immunology, microbiology or other related fields. The ideal candidate will be a team player, highly self-motivated, enthusiastic about problem solving and scientistic discovery. The successful applicant must have demonstrable competency or hands-on experience in one or more of the following areas: tissue culture, 3D organoid culture, design and fabrication of 3D materials, molecular biology work, bacterial culture, immunophenotyping assays, or Microfluidic fabrication. This position encompasses a range of responsibilities, including but not limited to: project planning, experimental design, method development, procedure execution, procedure modification as necessary, data collection and analysis, contribution to publications and reports, as well as effective communication and instruction. We are looking for candidates with a minimum of two years of availability, with positions to commence in or after May 2025.

Key Responsibilities & Essential Functions

  • Identifies problems, troubleshoots and analyzes variations observed and reported in regular testing protocols; modifies, refines or adapts techniques and procedures; modifies and/or adjusts quality control measures.
  • Monitors documentation of results; reviews and recognizes documentation which may lead to modification and adaptation of research methodologies; may collaborate with others.
  • Plans and monitors resources needed to operate the laboratory; maintains inventory control; coordinates space, field, equipment and/or facilities; may monitor expenditures.
  • Leads exchange of research information through demonstration and instruction.
  • Executes designated research tasks, making use of selected experiments, equipment, field work, library research, data acquisition and processing, statistical analysis or other investigative techniques.
  • May troubleshoot and modify experimental methods as well as perform data analysis functions.
  • Organizes and summarizes acquired data, using scientific and statistical techniques including computer programs.
  • Organizes and/or drafts material for the preparation of research papers, manuscripts, or other documents for publication and/or presentation.
  • Assists in grant writing and proposal development.
  • Conducts multiple experiments and is responsible for maintenance of equipment used in those experiments. Is organized, responsible and reports results clearly and efficiently to supervisor.

Knowledge, Skills, and Abilities

  • Experience required is 6 months to 1 year.
  • Demonstrated ability in development of research protocols.
  • Demonstrated success in coordinating and/or conducting multiple, concurrent assignments or a multi-faceted project.
  • Ability to interact with all individuals in a productive, professional, and positive manner to enhance the outcome of the goals of the research program.
  • Established understanding of good safety practices and a demonstrated history of safe conduct
  • Self-motivated with the ability to organize time effectively, demonstrated ability to manage details.
  • Advanced computer skills, ability to develop technical documents and presentations.
  • Demonstrated team player with professional, positive attitude and willingness to be flexible.
  • Ability to work flexible shifts (evening/weekend/holiday)
  • Regular, reliable, and consistent attendance

JAX has a vibrant and interactive research and training environment characterized by multidisciplinary scientific collaboration, unparalleled mouse resources, and outstanding core services. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities. In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 1.5-2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.

Pay range: $45,835 - $59,586

#CA-NL6

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org​​​​​​​.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

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Average salary estimate

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$45835K
$59586K

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What You Should Know About Research Assistant II, The Jackson Laboratory

The Jalili lab at JAX in Farmington, Connecticut, is on the lookout for a Research Assistant II who is passionate about diving deep into the realms of immunology and microbiology. This is an exciting opportunity to contribute to cutting-edge research focused on understanding host immune-microbiome crosstalk, especially in the context of infectious diseases, autoimmunity, and cancer. As part of a dynamic and interdisciplinary team, you'll find yourself engaging in a variety of experiments that range from 3D organoid cultures to developing innovative immune monitoring devices. No day is the same here! You’ll be hands-on with cellular and molecular biology techniques, assisting the principal investigator and postdoctoral associates with groundbreaking projects. The work will also involve managing animal models, performing bacterial cultures, and fabricating microfluidic devices. Beyond the lab work, you'll play a key role in the organization and operation of the lab, making it an excellent position for someone keen on enriching their research experience before advancing to graduate studies or an industry career. A bachelor’s degree in biomedical engineering, biology, immunology, microbiology, or a related field is essential, alongside at least six months to a year of relevant experience. In return, you’ll be part of a collaborative and innovative environment at JAX, where you can thrive professionally and personally, all while contributing to research that aims to enhance human health and well-being. If you're ready to take on a rewarding challenge and develop your skills, we can’t wait to hear from you!

Frequently Asked Questions (FAQs) for Research Assistant II Role at The Jackson Laboratory
What are the primary responsibilities of the Research Assistant II at JAX?

The Research Assistant II position at JAX involves a broad range of responsibilities, including project planning, experimental design, and executing procedures. You'll be responsible for tasks such as cell and bacterial culturing, as well as developing and fabricating microfluidic devices. Additionally, you'll work closely with the lab team to monitor documentation of results and contribute to publications and reports, making your role crucial in advancing the team's research efforts.

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What qualifications are required for the Research Assistant II role at JAX?

Candidates applying for the Research Assistant II role at JAX should hold a bachelor’s degree in biomedical engineering, biology, immunology, microbiology, or a closely related field. Furthermore, a minimum of six months to one year of hands-on experience in relevant areas such as tissue culture, molecular biology, or bacterial culture is preferred, enabling you to conduct experiments effectively and contribute to various research projects.

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What kind of laboratory techniques will I use as a Research Assistant II at JAX?

As a Research Assistant II at JAX, you will engage in various sophisticated laboratory techniques, including 3D organoid and organ-on-chip cultures, tissue culture, microfluidic fabrication, and immunophenotyping assays. Your role will also involve the use of animal models, which will provide a unique opportunity to work at the intersection of cutting-edge scientific research and practical applications in biomedical fields.

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How does JAX support the professional development of its Research Assistant II employees?

JAX is committed to nurturing the professional growth of its Research Assistant II employees through lab-based training, multidisciplinary collaboration, and unique programs aimed at enhancing skills in science communication, entrepreneurship, and laboratory management. This supportive environment prepares you for future career opportunities, be it in academia or industry.

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What is the expected availability for the Research Assistant II position at JAX?

The Research Assistant II position at JAX requires candidates to be available for a minimum of two years, with positions expected to commence in or after May 2025. This commitment allows you to immerse yourself fully in the lab's projects and contribute meaningfully to ongoing research efforts.

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Common Interview Questions for Research Assistant II
Can you describe your experience with tissue culture techniques relevant to the Research Assistant II position?

When answering this question, highlight specific tissue culture techniques you have experience with, such as how you handled cell lines, maintained aseptic conditions, and any relevant experiments performed. Discuss the outcomes or findings from your previous work that demonstrate your competence.

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What strategies do you use for data analysis and presentation in research?

In your response, mention various methods and software you are familiar with for data analysis, such as statistical software or programming languages like R or Python. Emphasize how you present data through charts and graphs to communicate findings effectively.

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How do you approach troubleshooting experiments in the lab?

In your answer, explain your systematic approach to troubleshooting, emphasizing your analytical skills and problem-solving mindset. Discuss any specific experiences where you identified an issue, tested hypotheses, and modified protocols to find a solution.

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Can you discuss a time when you collaborated with a team on a research project?

Share a specific example where you successfully collaborated with others in a research setting. Highlight your roles and responsibilities, communication strategies, and the project’s outcome to demonstrate your teamwork and collaboration skills.

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What are your thoughts on managing multiple tasks or experiments simultaneously?

Show your organizational skills by discussing how you prioritize tasks. You can mention tools or techniques you utilize, such as to-do lists or project management software, and how you ensure that deadlines are met without compromising on quality.

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How do you ensure compliance with safety protocols in the lab?

Discuss your understanding of safety protocols, your experience in maintaining a safe working environment, and elaborate on how you proactively monitor compliance and train others, emphasizing your dedication to safety in scientific research.

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Why are you interested in the Research Assistant II position at JAX?

Express your passion for the field of immunology and microbiology, and relate it to the research being conducted at JAX. Highlight any specific aspects of JAX’s work or culture that resonate with you and motivate you to apply.

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What molecular biology techniques are you familiar with that relate to this position?

List the molecular biology techniques you have experience with, such as PCR, gel electrophoresis, or cloning, and provide context or examples of how you have applied these techniques in past projects to demonstrate your skill.

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Describe how you would handle a situation where a colleague disagrees with your experimental approach.

Highlight your communication and conflict resolution skills by explaining how you would engage in a constructive discussion, listen to their perspective, and potentially adapt your approach based on valid feedback while keeping the project's goals in mind.

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What motivates you to conduct research in the field of immunology?

Share your passion for immunology and the impact it has on human health. You can mention personal experiences, academic interests, or stories that inspired your career path and how they connect to the mission of JAX.

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The Jackson Laboratory is an independent, non-profit biomedical research institution founded in 1929. We are an NCI-designated Cancer Center with 90 years of experience in genetics and genomics research.

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DATE POSTED
April 22, 2025

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