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Staff Scientist, Bioinformatics

Work ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeWork ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeDo you have a passion for innovative ideas and groundbreaking discoveries? With over $1 billion invested annually in R&D, at Thermo Fisher Scientific you’ll help solve some of the world’s toughest challenges, from giving cancer patients hope, ensuring safe drinking water, and helping law enforcement tackle cases through forensics. We empower our teams to put science into meaningful action and give our R&D colleagues the autonomy, resources, and tools they need to take science a step beyond.Discover Impactful Work:As a Staff Scientist, Bioinformatics, you will support the development and implementation of Next Generation Sequencing (NGS) based oncology assays within the Clinical Sequencing Division. You will leverage your expertise in oncology bioinformatics, Python programming, and Unix/Linux systems to develop and maintain bioinformatics pipelines, analyze complex genomic data, and ensure compliance with regulatory standards. Your work will directly contribute to advancing precision medicine and improving patient outcomes.A day in the Life:• Pipeline Development and Maintenance: Develop, optimize, and maintain bioinformatics pipelines and tools using Python and other relevant scripting languages on linux based platforms.• Data Analysis: Perform data analysis and interpretation of high-throughput sequencing data, including but not limited to DNA, RNA, cell free total nucleic acid datasets.• Collaboration: Work closely with cross-functional teams, including laboratory scientists, clinical researchers, regulatory professionals, and software developers, to design and implement bioinformatics solutions that meet project requirements.• Troubleshooting: Troubleshoot and resolve technical issues related to data processing and analysis, ensuring timely and accurate results.• Quality Control: Ensure data integrity, quality control, and compliance with regulatory standards throughout the development process.• Documentation: Document workflows, pipelines, and analysis results in a clear and reproducible manner, adhering to best practices in scientific research.• Continuous Learning: Stay up-to-date with the latest developments in bioinformatics, genomics, and computational biology, and apply this knowledge to improve existing pipelines and develop new solutions.Keys to Success:Education• Ph.D. or Master’s degree in Bioinformatics, Computational Biology, Molecular Biology, or a related field.Experience• At least 5 years of experience in bioinformatics, with a focus on oncology and Next Generation Sequencing (NGS).• Proven experience in Python programming, bash scripting, Unix/Linux systems, next generation sequencing analysis, and somatic oncology genomics• Strong understanding of bioinformatics tools and algorithms, including sequence alignment, variant calling, and functional annotation.• Experience with high-throughput sequencing data analysis (e.g., NGS, RNA-Seq, WGS, etc.).• Familiarity with version control systems (e.g., Github)• Experience working in regulated environments and familiarity with regulatory compliance and quality assurance standards.Knowledge, Skills, Abilities• Outstanding problem-solving skills and attention to detail.• Strong communication and collaboration skills, with the ability to work effectively in a multidisciplinary team.• Excellent documentation skills, with the ability to write clear and reproducible workflows.• Familiarity with cloud data platforms (e.g., AWS) and containerization technologies (e.g., Docker) is a plus.• Knowledge of statistical analysis and machine learning techniques is a plus.• Familiarity with databases and data management systems (e.g., SQL, NoSQL) is a plus.We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!Apply today! http://jobs.thermofisher.comThermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.Compensation And BenefitsThe salary range estimated for this position based in California is $118,500.00–$177,850.00This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:• A choice of national medical and dental plans, and a national vision plan, including health incentive programs• Employee assistance and family support programs, including commuter benefits and tuition reimbursement• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discountCompensation And BenefitsThe salary range estimated for this position based in California is $118,600.00–$177,850.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:• A choice of national medical and dental plans, and a national vision plan, including health incentive programs• Employee assistance and family support programs, including commuter benefits and tuition reimbursement• At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy• Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan• Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discountFor more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
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What You Should Know About Staff Scientist, Bioinformatics, Thermo Fisher Scientific

Are you ready to dive into the exciting world of bioinformatics? At Thermo Fisher Scientific in Austin, TX, we are on the lookout for a Staff Scientist, Bioinformatics who is not only passionate about innovative ideas but also eager to contribute to groundbreaking discoveries in oncology. With over $1 billion invested annually in our R&D, your role will significantly shape the future of precision medicine. You'll get to leverage your expertise in Python programming and Unix/Linux systems to develop and maintain bioinformatics pipelines that analyze complex genomic data. Each day will present new challenges as you work collaboratively with cross-functional teams to design solutions that meet project requirements. Imagine being part of a team that helps provide cancer patients with hope and advances our understanding of genomics! The Staff Scientist will ensure compliance with regulatory standards while performing data analysis and developing high-throughput sequencing tools. We’re here to support your continuous learning and growth in a vibrant culture that values integrity, intensity, and innovation. With competitive remuneration and comprehensive benefits, we strive to nurture talent and create impactful work environments. If you're ready to embark on this exciting journey with us and take science a step beyond, we encourage you to apply!

Frequently Asked Questions (FAQs) for Staff Scientist, Bioinformatics Role at Thermo Fisher Scientific
What are the key responsibilities of the Staff Scientist, Bioinformatics at Thermo Fisher Scientific?

As a Staff Scientist, Bioinformatics at Thermo Fisher Scientific, your key responsibilities include developing and maintaining bioinformatics pipelines using Python, analyzing complex genomic data, and collaborating with various teams to ensure effective implementation of bioinformatics solutions. You’ll also focus on troubleshooting and ensuring compliance with regulatory standards.

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What qualifications do I need to apply for the Staff Scientist, Bioinformatics position at Thermo Fisher Scientific?

To apply for the Staff Scientist, Bioinformatics position at Thermo Fisher Scientific, you should hold a Ph.D. or a Master’s degree in Bioinformatics, Computational Biology, Molecular Biology, or a related field, along with at least 5 years of bioinformatics experience focused on oncology and NGS.

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How does the Staff Scientist, Bioinformatics role contribute to advancements in oncology at Thermo Fisher Scientific?

The Staff Scientist, Bioinformatics role contributes to advancements in oncology by developing innovative bioinformatics methods and pipelines for Next Generation Sequencing data analysis, which plays a crucial part in the development of precision medicine solutions aimed at improving patient outcomes.

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What programming languages should a Staff Scientist, Bioinformatics at Thermo Fisher Scientific be proficient in?

A Staff Scientist, Bioinformatics at Thermo Fisher Scientific should be proficient in Python programming and have experience with Unix/Linux systems. Familiarity with bash scripting and experience in high-throughput sequencing data analysis are also essential.

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What is the work environment like for a Staff Scientist, Bioinformatics at Thermo Fisher Scientific?

The work environment for a Staff Scientist, Bioinformatics at Thermo Fisher Scientific is collaborative and dynamic. You will work in an office setting with a focus on teamwork, communication, and continuous learning, surrounded by highly skilled professionals passionate about advancing scientific research.

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Common Interview Questions for Staff Scientist, Bioinformatics
Can you describe your experience with NGS data analysis?

In answering this question, focus on discussing specific projects where you’ve analyzed NGS data, including the types of data you’ve worked with and any particular tools or algorithms you utilized. Highlight any challenges you faced and how you overcame them to ensure data accuracy.

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What are the key considerations when developing bioinformatics pipelines?

When developing bioinformatics pipelines, it's essential to consider data integrity, scalability, and compliance with regulatory standards. Mention the importance of documentation and reproducibility, as well as how you troubleshoot issues as they arise.

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How do you stay updated with the latest developments in bioinformatics?

Share your strategies for staying current, such as following industry journals, attending conferences, engaging with professional networks, and participating in online workshops or courses related to bioinformatics and genomics.

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What bioinformatics tools are you most familiar with?

Identify specific tools you have used in previous roles while explaining how you applied these tools in various projects. Whether it’s software for sequence alignment, variant calling, or data visualization, provide insights into your proficiency and usage.

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Can you explain the significance of quality control in bioinformatics?

In your response, emphasize that quality control is critical to ensure the reliability of results, discussing methods used for checking data quality and how you’ve implemented QA processes in your previous work.

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How do you approach collaboration with other scientists and teams?

Describe your collaborative experiences, detailing how you communicate effectively with cross-functional teams, manage differing viewpoints, and drive group consensus towards achieving project goals.

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What programming languages are you comfortable with, and how do you apply them?

Explain your proficiency in specific programming languages such as Python and bash, detailing real-world applications in developing scripts for data analysis, automation of tasks, or creation of bioinformatics tools.

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Describe a challenging data analysis project you have worked on.

Provide a detailed account of a specific project, the challenges you faced, the solutions you implemented, and the impact your work had on the project outcomes. Highlight your problem-solving capabilities.

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What regulatory standards have you worked with in your previous bioinformatics roles?

Discuss your familiarity with various regulatory frameworks relevant to bioinformatics and genomics, citing specific experiences where adhering to these standards was crucial for project success.

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How do you document your workflows and analysis results?

Illustrate your documentation practices by discussing the types of tools and formats you use to ensure reproducibility and clarity in documenting workflows, which can include using markdown formats, version control like Git, and comprehensive reporting structures.

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Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing ...

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December 23, 2024

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