Senior Director, Clinical Operations (24130-R-615-MED)

WHO WE ARE

Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We seek a talented and experienced Clinical Operations Senior Director to work HYBRID based in our SOUTH SAN FRANCISCO office. 

ArsenalBio’s mission and purpose are very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines to attack cancer’s inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy.

Driven by a collective of diverse experts across multi-scientific disciplines and clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients’ lives.

This means you’ll have the opportunity to work with the best talent in the field of cell therapy and be part of ONE TEAM, which advances therapies for patients who need it most.

Clinical Operations facilitates excellence in clinical trial execution and partners with Technical Operations to ensure drug product quality and delivery. The Clinical Operations Senior Director will be responsible for execution of clinical studies and program(s) and will build and manage clinical study teams. This role will work within a matrix team to enable productive interactions across technical operations and clinical functions. This role will require an ability to operate in a fast-paced, highly dynamic environment with partnerships that include both internal and external stakeholders.

• Manage all operational and strategic operational aspects of assigned programs
• Give input to Development activities for assigned studies
• Contribute to resource strategy for assigned programs
• Collaborate in the development of the target product profiles (TPPs) and CDPs by generating scenario plans, high-level forecasting of timelines, assessing global program-level feasibility, estimation and allocation of resources and budget, and development of high-level operational strategies
• Handle unique challenges and decisions that have an impact on programs and disease area.
• Develop and communicate budget, resource, risks and timelines to review bodies
• Operate at strategic level including input into risk management plans, value assessment and therapeutic area/indication expertise. Long-range planning horizon is typically 2 or more years
• Provide program leadership with oversight, guidance, and expertise to all staff assigned to the clinical program
• Coach and mentor Study Team Leaders and Clinical Trial Managers assigned to program on trial leadership activities and appropriately delegates development opportunities
• May serve as a team lead on non-program/ functional initiative work streams
• Develop good relationships with all important partners. Contribute at Core Team level beyond operations and able to give input into Development strategy
• Help hire and source strategy and improve resources
• Be a primary consultant to senior-level colleagues (eg, Project Team Leaders, Leaders & Medical Directors), functional leadership and stakeholders
• Work is accomplished independently with oversight from VP Development Ops to ensure understanding of broad disease and organizational strategies
• Lead and foster an environment supportive of innovation and smart risk-taking to bring and implement novel approaches to drug development
• Lead staff through organizational change and growth and provide input to senior management on changes and improvements
• Champion change with direct reports, dotted line reports and peers to sustain long-term goals
• Demonstrate  core Arsenal’s core values (One Team, Transparency, Humility, Sustainability) and the attributes that support these core values 
• Engage in crucial conversations by providing and receiving feedback supporting the growth and development of team members
• Demonstrate ability to engage and effectively influence team members across multidisciplinary teams while prioritizing multiple projects and meeting deadlines
• Drive curiosity, scientific rigor and excellent problem-solving skills across a fast-paced performance driven environment
• Innate ability to assess talent that will help grow the organization and add to Arsenal’s culture

• BS or equivalent advanced degree.
• 15+ years of experience in drug development with recent experience in oncology drug development and autologous cell therapy. 
• 13+ years of experience in managing complex teams.
• Proven track record of managing complex cell therapy studies, autologous cell therapy experience is required.
• Proven track record of managing complex early phase clinical trials in cell therapy or immuno-oncology.
• Experience managing direct reports 
• Knowledge of advanced information technology to facilitate complex clinical monitoring.
• Excellent understanding of regulatory processes and clinical development.
• Excellent organizational skills and ability to prioritize and deliver results.
• Excellent communication and influencing skills and proven ability to lead in a matrix environment.
• Creative and innovative leadership with a sharp objective intellect and experience balancing big picture thinking with detailed analysis.

BENEFITS AND PAY

ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra “Arsenal Days of Rest” every quarter for employees to recharge. 

Our people-first culture cultivates a deep respect for humanity, not only in those we serve but also in one another. We take pride in being part of a company that values and celebrates diversity—in experiences, ideas, and interests. We are empowered in an environment that embraces unity and inclusivity, fostering a sense of belonging and mutual respect.

We provide powerful tools to empower our employees to take charge of their career paths and reach their full potential. At ArsenalBio, we believe in investing in our employees' well-being—both professionally and personally—because our people are our most valuable asset. Our essential team members bring exceptional expertise in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software, and other fields to turn the possibilities of tomorrow into the realities of today.

We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients.

We are an equal opportunity employer and deeply value diversity within our company. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability.

The estimated base salary for the preferred primary location of the San Francisco Bay area ranges from $224,500–$275,000. Salary ranges for other locations may vary.  Base pay offered may vary based on job-related knowledge, experience, education, and location. Beyond these considerations, we are committed to pay equity and consider the internal equity of our current employees when making any final offers.

To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias or to ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes.

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