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Executive Director, Strategic Sourcing and Supply Chain

Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company focused on developing cell therapies for patients suffering from autoimmune diseases. The Kyverna therapeutic platform leverages advanced T cell engineering to suppress and eliminate autoreactive immune cells at the origin of autoimmune and inflammatory diseases. Be at the forefront of cell therapy innovation by joining scientists, industry veterans and healthcare visionaries and help transform how autoimmune diseases are treated


Title:                Executive Director, Strategic Sourcing & Supply Chain

Reporting to: SVP, Manufacturing, Sourcing and Supply

Location:        Emeryville (Hybrid)


Kyverna is recruiting a highly motivated Strategic Sourcing Head responsible for building the Strategic Sourcing operation at Kyverna to source, evaluate, select and manage critical components of the Kyverna business, and continuing to build manage and optimize the Supply Chain function across the Kyverna portfolio of products, clinical sites and regions where Kyverna products are made available. The ideal candidate will contribute to our goals of navigating what’s next in synthetic biology, immunology and cell engineering while living our core values: Bring Intellectual Rigor, Elevate Each Other, and Stay True To Why. 

 

The Strategic Sourcing and Supply Chain Head will be responsible for establishing the Sourcing and Procurement functions, managing the selection and implementation of critical supply components to the Kyverna Business across the supply chain including suppliers of critical materials, Build vs Buy opportunities for manufacturing of cell products, logistics services, and other fundamental components of the business to optimize the value chain in line with the Corporate Strategy. 


Responsibilities
  • Build and establish the Sourcing function and operations including the components of the operations needed to evaluate and select critical supply components of the business.
  • Source, Evaluate, and Select components of the Supply Network including, but not limited to, Manufacturing Organizations, Technology Providers, Critical Material providers (Vector, LNP, Cells, Cell Lines, and Other). 
  • Lead and provide the tools and framework for the cross functional assessment of suppliers, vendors and partners for their capabilities, business stability, and quality of service. 
  • Negotiate and implement major contracts related to manufacturing, development, procurement of critical materials, and logistics management with a balanced focus on cost, time and capabilities. Make strategic recommendations to the Kyverna Leadership on areas of growth, expansion, exit or contraction.
  • Monitor the landscape, assess, categorize and communicate opportunities to evaluate the on-going directory of potential suppliers/services that help advance Kyverna's business. Maintain the directory, eliminating suppliers/providers with unfavorable prior assessments and adding new suppliers/providers as they are identified.
  • Provide strategic input, including capacity and capability planning and management, supporting the expansion of the Kyverna footprint globally. Assist teams in building the full business case with risks, opportunities and recommendations that support the growth of Kyverna.
  • Identify areas of need for supply redundancy based on business risk. 
  • Recommend and establish strategic partnerships and opportunities for consolidation that reduces overall business complexity and risk.
  • Partner with stakeholders in Business Development, Legal, Manufacturing, Quality, Technical Development, Clinical Development and Life-cycle Leadership to identify, evaluate, and implement opportunities to establish efficient supply networks that support the corporate vision and strategy.
  • Manage and optimize the Supply Chain function to ensure timely, cost-effective, and robust management of all materials and products to all regions where Kyverna product is provided.
  • Set up Supply Lanes and evaluate requirements in new regions where clinical trials are being considered, assessing import/export requirements, taxes, tariffs, and supply constraints for autologous cell therapy products.
  • Provide the Supply Plan to S&OP and set targets that ensure robust supply planning and forecasting.
  • Strategically allocate supply across the supply network to ensure redundancy, un-interrupted supply, and cost effectiveness.
  • Set-up and manage inventory of all materials managed by Kyverna. Source Depots for import/export management, and warehouses for storage of samples and critical materials. Set re-supply levels.
  • Build, manage and develop the team of sourcing, supply chain and procurement personnel into a high-functioning team. Plan algorithms for additional personnel based on work volume, drum-beat and regional presence. 


Requirements
  • A bachelor’s degree in life sciences is required.
  • An advanced degree in life science and/or an MBA is preferred.
  • 15+ years in Pharmaceutical or Biopharmaceutical operations with 5+ years managing sourcing or supply chain. Experience is cell therapy required.
  • Proven track-record of excellence in managing complex supply chains with internal and external stakeholder and optimizing cost and performance. 
  • Proven leader able to manage teams and collaborate with cross-functional groups and executives of the company to advance ideas and implement solutions while balancing speed, cost, quality, and risk.
  • Accountable, independently motivated, detail oriented and good problem-solving ability.
  • Able to understand business needs, recommend options with realistic alternatives, and make decisions based on changing priorities.
  • Demonstrated ability to engage and influence internal and external team members at all levels in a matrixed environment to achieve objectives and effectively communicate challenging goals and objectives.
  • Highly collaborative team player who fosters open communication and facilitates mutual understanding and cooperation between all stakeholders.
  • Strategic and critical thinker who has excellent judgement when making trade-off decisions for program scope, costs and strategy.
  • A mentor and leader: all team members deserve an engaged, thoughtful culture and people leader.
  • Excellent verbal, written and presentation skills and effectively communicates with all levels of management.
  • Ability to build strong relationships throughout the organization by being transparent, reliable, and delivering on commitments.
  • Self-starter who works effectively in teams.


The base salary range for candidates residing in the California Bay Area for this position is $260,000 to $300,000 annually. This salary range is an estimate of what we reasonably expect to pay for this posted position, and the actual salary may vary based on various factors that may include but are not limited to quality and length of experience, education, geographic location and alignment with market data.

 

Kyverna is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Kyverna is committed to the principle of equal employment opportunity for all employees and does not discriminate on the basis of race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other legally protected status. EOE/AA/Vets



Kyverna is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Kyverna is committed to the principle of equal employment opportunity for all employees and does not discriminate on the basis of race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other legally protected status. EOE/AA/Vets

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CEO of Kyverna Therapeutics
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Dominic Borie
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What You Should Know About Executive Director, Strategic Sourcing and Supply Chain, Kyverna Therapeutics

At Kyverna Therapeutics, we're excited to welcome an Executive Director of Strategic Sourcing and Supply Chain to our innovative Emeryville, CA team! Here, you'll be at the forefront of game-changing cell therapy advancements, where we passionately develop treatments for autoimmune diseases using groundbreaking T cell engineering. This role is perfect for someone eager to build and optimize strategic sourcing operations that are crucial for our clinical-stage biopharmaceutical journey. As the Executive Director, you’ll orchestrate the sourcing of critical components and manage the supply chain functions that ensure our products reach the patients who need them most. Your leadership will guide cross-functional teams, negotiate key contracts, and maintain a directory of top-tier suppliers to navigate the competitive landscape of cell therapy. You’ll be responsible for identifying growth opportunities and mitigating risks, ensuring we maintain an efficient supply network across all operational aspects. If you're a detail-oriented, collaborative leader with a strong background in biopharmaceutical operations, particularly in cell therapy, you're exactly who we're looking for. Join us and help shape the future of medicine while living out our core values: Bring Intellectual Rigor, Elevate Each Other, and Stay True To Why.

Frequently Asked Questions (FAQs) for Executive Director, Strategic Sourcing and Supply Chain Role at Kyverna Therapeutics
What are the key responsibilities of the Executive Director, Strategic Sourcing and Supply Chain at Kyverna Therapeutics?

The Executive Director at Kyverna Therapeutics is responsible for establishing sourcing operations, sourcing critical components, and managing the overall supply chain. This role includes evaluating suppliers, negotiating contracts, and ensuring timely, cost-effective delivery of materials for our innovative cell therapies.

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What qualifications are required for the Executive Director position at Kyverna Therapeutics?

Candidates for the Executive Director role at Kyverna Therapeutics should ideally have a bachelor’s degree in life sciences, with an advanced degree or MBA preferred. You'll need 15+ years in pharmaceutical operations, with at least 5 years in sourcing or supply chain, and specific experience in cell therapy is essential.

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How does the Executive Director contribute to Kyverna Therapeutics' corporate strategy?

The Executive Director of Strategic Sourcing and Supply Chain at Kyverna Therapeutics plays a crucial role in aligning sourcing operations with corporate strategy by recommending growth opportunities, assessing supplier capabilities, and optimizing the supply chain to support the company's vision of advancing cell therapy treatments.

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What skills are important for the Executive Director role at Kyverna Therapeutics?

Important skills for the Executive Director role include strong leadership, strategic thinking, excellent communication abilities, and proven skills in managing complex supply chains. A collaborative mindset is critical as you work with cross-functional teams to make decisions that balance speed, cost, and quality.

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What can candidates expect for the salary range as an Executive Director at Kyverna Therapeutics?

The salary range for the Executive Director, Strategic Sourcing and Supply Chain position at Kyverna Therapeutics in the California Bay Area is estimated to be between $260,000 to $300,000 annually. Actual compensation may vary based on experience, education, and market alignment.

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Common Interview Questions for Executive Director, Strategic Sourcing and Supply Chain
Can you describe your experience in managing sourcing operations in the biopharmaceutical industry?

A strong answer should include specific examples of your previous roles in sourcing, highlighting your achievements in negotiating contracts, selecting suppliers, and optimizing supply chains to improve efficiency and reduce costs.

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How do you assess and choose suppliers for critical materials?

Discuss a systematic approach you use to evaluate suppliers based on quality, reliability, stability, and cost, along with any frameworks or tools that have worked effectively in your previous roles.

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What strategies would you employ to ensure supply chain continuity?

Explain your experience with risk assessment and management in the supply chain, mentioning specific strategies like redundancy planning, establishing multiple sourcing options, and monitoring supplier performance.

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How would you handle conflicts between suppliers and internal stakeholders?

Utilize examples where you successfully mediated disputes, emphasizing your communication skills, ability to foster collaboration and your understanding of both supplier needs and internal objectives.

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What role does data analysis play in your decision-making process for strategic sourcing?

Illustrate your proficiency in using analytics tools and data to drive decisions regarding supplier selection, negotiating terms, and forecasting needs, ensuring that your strategies are data-informed and effective.

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Can you discuss a time when you had to pivot due to supply chain disruptions?

Provide a clear narrative detailing the disruption, your immediate response, and how you enacted a plan to mitigate future risks to illustrate your problem-solving and adaptability skills.

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What are your thoughts on the future of sourcing in the biopharmaceutical sector?

Share insights on emerging trends in the industry, like digital transformation in supply chains and the increasing importance of sustainability, while tying these trends back to your sourcing strategies.

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How do you prioritize projects and initiatives within your team?

Speak about your method for prioritization, including how you evaluate urgency against potential impact, your collaboration with stakeholders, and how you keep your team focused on strategic goals.

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What metrics do you consider most important when evaluating supply chain performance?

Discuss key performance indicators such as on-time delivery, cost savings, supply chain lead time, and supplier performance, highlighting how you use these metrics to drive improvement.

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How do you ensure cross-departmental collaboration in sourcing initiatives?

Share examples of successful cross-departmental projects, emphasizing how open communication, regular updates, and collaborative strategy sessions foster alignment between sourcing and other functions.

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We are bringing curative medicines to life to free patients from the siege of autoimmune disease.

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Full-time, hybrid
DATE POSTED
December 14, 2024

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