Director, Clinical Sciences

As the Director, Clinical Sciences at Tango Therapeutics, your primary responsibilities will include leading the development and execution of clinical studies, collaborating with cross-functional teams to ensure compliance with regulatory requirements, authoring trial documents, and providing scientific input for commercial strategies. You'll also mentor junior scientists and enhance clinical development processes, making a significant impact on the company's oncology programs.

To qualify for the Director, Clinical Sciences role at Tango Therapeutics, you should hold an MD, PhD, PharmD, or MS in a relevant scientific discipline. Additionally, at least 10 years of clinical science experience, including a minimum of 3 years in oncology, is required. Candidates must demonstrate expertise in designing and managing clinical trials, possess strong analytical skills, and have excellent communication abilities.

The ideal candidate for the Director, Clinical Sciences position at Tango Therapeutics is someone with extensive experience in clinical science, particularly in oncology. They should exhibit strong analytical capabilities, proficiency in statistical analysis, and a passion for mentorship. Successful candidates will also have the ability to communicate complex scientific concepts clearly to diverse audiences and thrive in fast-paced work environments.

In their role, the Director, Clinical Sciences at Tango Therapeutics will collaborate closely with teams such as clinical operations, biostatistics, and pharmacovigilance. This collaboration is crucial to ensure that clinical trials are executed on time and in compliance with all regulatory requirements, thereby achieving the project's overall goals efficiently.

The Director, Clinical Sciences position at Tango Therapeutics not only offers the chance to lead innovative clinical programs but also provides numerous opportunities for professional development and mentorship. As you guide junior scientists and contribute to process enhancements, you'll strengthen your leadership skills and make impactful contributions to groundbreaking oncology therapies.

In your response, focus on specific trials you’ve led, detailing your role in designing study protocols, managing trial execution, and ensuring compliance with GCP. Share challenges you encountered and how you overcame them, demonstrating your problem-solving skills and adaptability.

Discuss your experience with regulatory submissions and your understanding of guidelines such as GCP and IND applications. Emphasize how you have previously engaged with regulatory authorities and maintained rigorous compliance standards throughout trials.

Highlight your communication skills and specific examples where you've successfully collaborated across diverse teams. Discuss how you facilitate team meetings, align project goals, and resolve conflicts to achieve optimal outcomes.

Explain your proactive approach to identifying potential risks and your methods for quickly addressing issues. Share an example where your strategic thinking led to effective problem resolution.

In your answer, provide a specific instance where you successfully guided a junior colleague through a challenging aspect of their role. Highlight how your mentorship not only supported their development but also contributed positively to the team's overall success.

Describe your analytical skills and your experience in interpreting clinical data. Discuss how you utilize this data to inform decision-making and strategy, contributing to trial adjustments or new hypotheses.

Talk about the resources you utilize—such as journals, conferences, and professional networks—to stay informed about the latest research in oncology. Share how this continuous learning influences your clinical strategies.

Discuss the types of protocols you have authored, emphasizing your understanding of what constitutes a robust protocol. Describe your methods for ensuring clarity, compliance, and alignment with study objectives.

Elaborate on your communication techniques for translating complex scientific data into easily understandable insights. You might share a specific example where your approach successfully engaged diverse audiences.

Answer by discussing factors like strong leadership, effective communication, rigorous adherence to protocols, and patient engagement. Provide examples to illustrate how these elements contributed to your past trial successes.