Genesis Therapeutics is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation. We are seeking a Senior CADD Scientist to join our on-site discovery team in San Diego, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US.
Genesis Therapeutics is unifying AI and biotech to discover novel and breakthrough treatments for patients with severe and devastating conditions. Genesis was founded on groundbreaking molecular ML research and since has established itself as the industry leader in AI for small molecule drug discovery. Our team of accomplished biotech leaders and expert drug hunters joins forces with deep learning researchers and software engineers who are pioneering predictive and generative AI technologies for molecules.
Our team has created the industry's most advanced molecular AI platform called GEMS (Genesis Exploration of Molecular Space), to accelerate and optimize small molecule drug discovery and to enable the discovery of novel first-in-class and best-in-class small molecule drugs for challenging and/or undruggable targets.
The company has leveraged GEMS to build an internal pipeline with multiple programs against high-value targets, including data-poor and canonically undruggable targets where GEMS is uniquely advantaged. In addition, Genesis has signed AI-focused platform collaborations with major pharmaceutical companies, including most recently Incyte Corporation (Feb 2025) and Gilead Sciences (Sept 2024).
We raised a $200M series B in August 2023, and have raised over $300M in funding from top technology and biotech investors, including Andreessen Horowitz, Rock Springs Capital, T. Rowe Price, Fidelity, Radical Ventures, NVentures (NVIDIA's VC arm), BlackRock, and Menlo Ventures.
Genesis is headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.
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At Genesis Therapeutics, we're on a mission to transform drug discovery with the most advanced AI technologies, and we're in search of a talented Senior CADD Scientist to join our dynamic team in San Diego. In this exciting role, you'll get to work side-by-side with leading scientists in our sophisticated wet lab, pushing boundaries with cutting-edge machine learning and biophysical simulations. Here, you will lead small molecule drug discovery initiatives across a wide array of targets—some of which present unique challenges. Your expertise will be crucial as you utilize state-of-the-art CADD tools, engage in virtual screening, molecular simulation, and make vital predictions regarding potency and ADMET. Collaborating closely with medicinal chemists, you'll help craft tailored computational approaches for our projects. Plus, you’ll act as the vital link between computational and medicinal chemistry teams, fostering communication and collaboration that drives innovation. If you're ready to thrive in a fast-paced environment that encourages quick iteration and creativity, this role is perfect for you! Join us at Genesis Therapeutics and help us harness AI to develop groundbreaking treatments for those in need.
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