Principal Research Scientist I, Analytical R&D (Peptides)

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Group Overview: 

AbbVie Analytical Research & Development (Analytical R&D) is a global analytical scientific organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products.  Our scope includes AbbVie's diverse pipeline of innovative small molecule medicines and spans from the selection of Discovery candidate molecules through Early-Stage Clinical Development.  We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines.  Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.  We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates. 

Position Overview:

The Small Molecule Analytical Research and Development group is seeking a Peptide Analytical Chemist, Principal Research Scientist I to conduct process research and development of small molecules, including Peptides, and/or antibody-drug conjugates from pre-clinical through early clinical phases. 

Key Responsibilities: 

• The candidate will participate and/or lead analytical teams associated with drug substance and drug product development and characterization of peptides and other modalities. 
• Responsible for fit-for purpose method development, testing procedures, justifying specifications, and implementation of analytical control strategies to help the advancement of drug discovery candidates. 
• Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management.  
• Mentor and develop scientific staff in troubleshooting strategic and experimental issues and foster a culture of knowledge sharing. 
• Leverage prior experience to author and review key regulatory documents, laboratory data, technical memos and reports. 
• The position involves multi-disciplinary collaborations across Discovery, Development, Manufacturing, and Regulatory to execute and deliver material and information for clinical trials and regulatory submissions.  
• The candidate will identify and nurture ideas for continuous improvement activities and initiatives within the department. 
• This role may include management of direct reports. 

• Bachelor’s, Master’s, or PhD Degree in Analytical Chemistry with typically 14+ (BS), 12+ (MS) or 6+ (PhD) years of experience. Candidates with less experience may be considered for other opportunities. 
• Experience with analytical aspects of advancing peptide modalities. 
• Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to represent analytical in cross-functional development teams. 
• Hands on experience with HPLC analysis and method development along with fundamental understanding and working knowledge of various analytical techniques including Dissolution, MS, GC, and NMR.  
• An understanding of global regulatory expectations and experience with authoring development reports and regulatory filings is highly desirable. 

Key AbbVie Competencies: 

Interacts well with diverse groups within function and maintain strong working relationships with internal and external collaborators to enable higher performance.  

• Learns fast, grasps the "essence" and can change course quickly where indicated. 
• Raises the bar and is never satisfied with the status quo. 
• Creates a learning environment, open to suggestions and experimentation for improvement. 
• Embraces the ideas of others, nurtures innovation and manages innovation to reality. 

Level and compensation will be commensurate with experience. 

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• ​This is an on-site position based out of AbbVie's campus north of Chicago. 
• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
• This job is eligible to participate in our short-term incentive programs. ​
• This job is eligible to participate in our long-term incentive programs​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html