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Director, Clinical Science

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An integral member of the Janux Therapeutics’ Clinical Development team; the Director, Clinical Science will participate in the evaluation, strategic planning, design and execution of the drug development strategies of our current and future clinical-stage programs. The incumbent will work closely with the Clinical Operations team members to support and execute upon clinical trial conduct. In addition, they will support the assigned Clinical Lead with various deliverables necessary for successful clinical trial execution.

ESSENTIAL FUNCTIONS AND RESPONSIBILITIES:

Support the design and implementation of development strategies for programs entering the clinic, providing strategic clinical science input for all assigned programs
Collaborate cross functionally with Clinical Operations team members to support the design and execution of clinical trials. This may include assistance in the development of essential clinical trial documents such as protocols, ICF documents/amendments, CRF’s, CSR’s, and Investigator Brochures
Aid in the development of the Data Review Plan and Data Review Strategy, ensuring that protocol-level deviations, eligibility criteria, study assessments & other aspects of the protocol are implemented consistently across the study
Perform clinical data review and identify clinical data insights through ongoing patient level review and trends analysis, working cross-functionally to monitor clinical data
Promote quality review of data with an emphasis on subject safety and eligibility, data integrity, trend identification, analysis and remediation, and identification of AEs/SAEs for medical review
Support ad-hoc Regulatory activities such as contributing by authoring/reviewing clinical portions of Regulatory Documents and/or posters, abstracts and manuscripts, and the preparation and conduct of meetings with regulatory agencies and/or external drug development consortiums
Develop and deliver upon clinical presentation slides and other materials for internal and external meetings
Maintain scientific and clinical knowledge in the specific therapeutic and disease areas of assignment
Other duties as required

EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS AND ABILITIES

Advanced degree in Life Sciences preferred
Minimum 8 years of industry experience, 5+ years of which dedicated to the conduct of clinical trials as a Clinical Scientist
Knowledge of Oncology drug development and clinical trial processes, study design, statistics and clinical operations within a similar biotech and/or pharmaceutical environment
Skills to support program-specific data review and trend analysis
Knowledge of the establishment and operation of data monitoring committees, dose review teams, and independent response adjudication committees
Knowledge of GCP and regulatory requirements
Ability to critically evaluate data, literature and presentations
Ability to lead and work with cross-functional teams
Strong project management skills

$205,000 - $240,000 a year

In addition to a competitive base salary ranging from $205,000 to $240,000, we offer stock options, restricted stock units, a stock purchase plan (ESPP) and a target bonus. Janux also provides a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, and supplemental disability insurance.

Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, and internal equity.

Job Type: Full-time

Benefits:

· 401K

· Medical insurance

· Dental insurance

· Vision insurance

· Supplemental disability insurance plans

· Flexible schedule

· Life insurance

· Flexible vacation

· Sick time

· Incentive stock option plan

· Relocation assistance

Schedule:

· Monday to Friday

Work authorization:

· United States (Required)

Additional Compensation:

· Annual targeted bonus X%

Work Location:

· On site (San Diego, CA)

EQUAL OPPORTUNITY EMPLOYER:

Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.

Notice to Recruiters and Third-Party Agencies

The Talent Acquisition team manages the recruitment and employment process for Janux. To protect the interests of all parties involved, Janux will only accept resumes from a recruiter once a fully-executed search agreement is in place. Agencies are hereby specifically directed not to contact Janux employees directly in an attempt to present candidates. Janux will consider any candidate for whom an Agency and/or Recruiter has submitted an unsolicited resume to have been referred, free of any charges or fees.

Average salary estimate

$222500 / YEARLY (est.)

min

max

$205000K

$240000K

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What You Should Know About Director, Clinical Science, Janux Therapeutics

Janux Therapeutics is on the lookout for a dynamic Director of Clinical Science to join our dedicated Clinical Development team in sunny San Diego, CA. This is a remarkable opportunity to play a key role in the strategic planning, design, and execution of our clinical-stage programs. As the Director, Clinical Science, you'll work closely with Clinical Operations to ensure our clinical trials run smoothly and successfully. Your experience will shine as you contribute to the creation of vital clinical trial documents including protocols and investigational brochures. You'll perform clinical data reviews and provide insights to ensure participant safety and data integrity. Plus, your leadership will help guide our regulatory activities, from preparing presentations for external meetings to engaging with regulatory agencies. With a strong background in Oncology drug development and clinical trial processes, you’ll be instrumental in shaping the future of our innovative therapies. If you’re ready to take your career to the next level with a company that values quality and collaboration, Janux Therapeutics is the place for you!

Frequently Asked Questions (FAQs) for Director, Clinical Science Role at Janux Therapeutics

What are the essential responsibilities for the Director, Clinical Science at Janux Therapeutics?

The Director, Clinical Science at Janux Therapeutics is responsible for designing and implementing drug development strategies for clinical programs. This role involves collaboration with the Clinical Operations team to support trial execution, developing essential clinical documents, performing data reviews, promoting quality assurance in trial data, and assisting with regulatory submissions. This leadership position ensures that all aspects of clinical trials align with company objectives and regulatory standards.