Senior Software Engineer
Xilis, Inc. is an innovation-driven biotech company developing its proprietary MicroOrganoSphere (“MOS”) Technology for functional precision oncology. Xilis’ MOS Technology enables rapid and scalable generation of patient tumor models that retain patient-specific tumor biology and tumor microenvironment, representing one of the most translationally-relevant ex vivo technologies for precision oncology drug discovery and development. Located in Research Triangle Park, Durham, NC, Xilis is building a functional precision medicine platform that incorporates scaled multi-modal profiling of therapeutic activity and AI/ML-enabled analytics to catalyze functional precision medicine drug discovery, development and diagnostics. Collectively, Xilis aims to harness its MOS Platform to enable development of the most effective therapeutics and guide them to the right patients at the right time.
Impact
Your work will directly contribute to advancing cancer care through innovative technology. Our proprietary MOS hardware is a sophisticated microscale encapsulation system for manipulating and studying complex 3D tissue models, combining microfluidics, extracellular matrices, robotics, and specialized protocols. Xilis As Senior Software Engineer, you will play a crucial role in enhancing this revolutionary platform that guides precision therapy for cancer patients and accelerates drug discovery and development.
- Design, develop, and support the device software for our revolutionary MicroOrganoSphere (MOS) technology
- Enhance device capabilities by implementing sensor integration and data collection systems that maximize device efficiency and performance
- Develop additional applications and features to support MOS creation and functional assays
- Collaborate with cross-functional hardware engineering and data science teams to drive innovation in our tech platform
- Integrate diverse sensors and hardware components using manufacturer libraries and SDKs
- Develop and design software logic systems for error detection, handling, and response, based on system readouts from hardware components
- Create robust data pipelines to synchronize device data with our AWS data lake
- Build intuitive, responsive on-device user interfaces
- Implement comprehensive logging and monitoring systems for device operations
- Collaborate with data scientists to develop and deploy device-specific algorithms that enhance operational efficiency and output quality
- Troubleshoot and resolve software issues to ensure reliable device operation, including PCBs and onboard computers
- Develop and maintain standard operating procedures (SOPs) for device operation to support laboratory workflows
- 7+ years of professional software engineering experience focused on embedded systems, device drivers, and integration with hardware components.
- Strong understanding of hardware-software integration, embedded systems, real-time processing, and how to interface with physical devices (e.g., sensors, actuators, communication buses, PCBs, microcontrollers).
- Proficiency in Python for instrument control, data acquisition, and device communication protocols
- Experience building and integrating APIs on AWS
- Experience with Git version control, CI/CD pipelines, and agile development
- Experience with Linux systems
- Bachelor’s degree in Electrical Engineering, Computer Engineering, or related technical field
- Background in life sciences or biotechnology
- Knowledge of regulatory requirements for laboratory instrumentation
- Background in electrical engineering or hands-on experience with hardware fundamentals such as signal processing, circuit-level debugging, or hardware bring-up.
- Prior experience with microfluidics or lab automation systems
- Experience with C/C++ for performance-critical applications
- Knowledge of UI/UX design principles for instrumentation interfaces
Xilis was created when its three founders — an engineer, a physician, and a biologist — decided to come together and commercialize their technology to transform cancer care. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. We do not discriminate on the basis of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status. Furthermore, even if your work experience isn't perfectly aligned with what we've described above, if you're excited about what we're building then we want to talk to you!
Xilis offers comprehensive health, vision, dental & retirement plans, and unlimited PTO. We are a remote-friendly team: our headquarters are in Durham, North Carolina, but we have team members across the US (and beyond!).
Average salary estimate
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Join Xilis, Inc. as a Senior Software Engineer and be part of a groundbreaking team that's changing the landscape of precision oncology! Based in the vibrant Research Triangle Park of Durham, NC, Xilis is on a mission to revolutionize cancer treatment with our innovative MicroOrganoSphere (MOS) Technology. Your expertise will play a pivotal role in designing and developing software that powers our sophisticated microscale encapsulation system, enabling the creation of patient-specific tumor models. In this role, you'll work closely with cross-functional teams, including hardware engineers and data scientists, to enhance device capabilities through sensor integration and robust data pipelines. If you are enthusiastic about developing applications that push the boundaries of precision therapy, and accelerating drug discovery, then this is the ideal opportunity for you! Bring your 7+ years of software engineering experience, especially in embedded systems, and utilize your skills in Python, AWS, and Linux systems to build intuitive interfaces and streamline device operations. You won't just be coding; you'll be making a direct impact on cancer care technology. Our culture thrives on diversity and innovation, welcoming anyone excited about our mission to transform how we fight cancer. With a comprehensive benefits package, including unlimited PTO and remote-friendly work arrangements, your work-life balance is important to us. Come and contribute to a project that truly matters at Xilis!
Based in Durham, North Carolina, Xilis, Inc. is a biotechnology company developing a precision oncology platform that guides treatment decisions for oncologists to improve cancer care outcomes for patients and supports drug discovery and developme...
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