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Postdoctoral Fellow

Your group

The Cortes-Ciriano group studies the mutational processes and mechanisms of genome instability underpinning tumourigenesis, immune escape, and drug response through the analysis of high-throughput sequencing data from clinical samples. The group is also leading the development of novel approaches for early cancer detection using long-read sequencing. More information about the group can be found here.

Your role 

We invite applications for a Postdoctoral Fellow position in the fields of early detection, cancer genomics and long-read sequencing data analysis. We are looking for an intrinsically motivated, talented, and hypothesis-driven individual with experience in analysing high-throughput sequencing data sets. This position is an excellent opportunity for individuals looking to gain in-depth knowledge and expertise in genomic medicine and long-read sequencing data analysis.
You will be expected to lead the development of scalable and creative computational solutions for sequencing data analysis. Specifically, your project will involve developing computational methods for analysing a unique collection of hundreds of long-read whole-genome sequencing data sets from human tumours and cell-free DNA samples spanning multiple cancer types, including adult and paediatric tumours. It is essential that you are dedicated to lead your own project while also being a team player and willing to engage with our national and international collaborators.

You will enjoy substantial freedom (if desired) to design novel algorithms and to explore your own hypotheses. Your project will benefit from close interactions with our clinical and wet-lab collaborators.

You have 

  • PhD degree in the life sciences (preferably computational biology, genomics, statistics, or a similar field)
  • Strong analytical and programming skills (preferably in python and R)
  • Significant experience in computational genomics (ideally in cancer genomics) as evidenced by publication record
  • Demonstrated ability to work both independently and collaboratively with other group members and external collaborators
  • Proficient communication skills in both written and spoken English
  • Experience in Unix-based environments, high-performance computing and the development of reproducible data analysis pipelines using version control software
  • Data science skills, such as visualisation of complex data sets

You may also have

  • Background in cancer biology
  • Experience in long-read sequencing data analysis is desired but not required

Other Helpful Information

  • At EMBL-EBI we are pleased to offer hybrid working options for all our employees. Our research teams spend 4 days working from the office, in our new Thornton Building.
  • If you are interested please submit a cover letter/ motivation letter, CV and 2 letters of recommendation to be uploaded as part of your application. Applications which have this information missing will not be considered.

Contract length: 2 years

Salary: Monthly stipend of £3,307 per month after tax


Professional development support

The EMBL Fellows’ Career Service provides support and guidance to predoctoral and postdoctoral fellows across all six EMBL’s sites.

Working with a dedicated Careers Advisor, this invaluable service will help you to take informed decisions about your career planning both in the short and longer term. Whether your main interest is pursuing a career path in academia, exploring opportunities in industry or exploring an independent venture, the EMBL Fellows’ Career Service with provide you with a portfolio of activities and resources to help you.

To find out more please visit - EMBL-fellows-career-service

Why join us

Join a culture of innovation 
We are located on the Wellcome Genome Campus, alongside other prominent research and biotech organisations, and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued, supported and empowered to reach their professional potential. 

Enjoy lots of employee benefits:

  • Financial incentives: Monthly family and child allowances, generous stipend reviewed yearly, pension scheme, death benefit and unemployment insurances

  • Flexible working arrangements including hybrid working patterns 

  • Private medical insurance for you and your immediate family 

  • Generous time off: 30 days annual leave per year in addition to public holidays

  • Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely)

  • Family benefits: On-site nursery (Heidelberg & Hinxton), 10 days of child sick leave, paid maternity & parental leave, holiday clubs on campus and monthly family and child allowances

  • Benefits for non-residents: Visa and financial support to relocate if you're overseas


What else you need to know

  • International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants. 

  • Diversity and inclusion: At EMBL, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ & individuals from all nationalities. 

  • Job location: All our fellowships are based on-site (for at least part of each week). If you are living overseas, you will receive a generous relocation package to support you. 

  • EMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes here.

  • Watch this video to find out what it's like to be a Postdoc at EMBL-EBI.

  • How to apply: To apply please submit a cover letter and a CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date below.

Closing Date

04/05/2025


 

Average salary estimate

$39704 / YEARLY (est.)
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$39704K
$39704K

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What You Should Know About Postdoctoral Fellow, EMBL

Join the innovative Cortes-Ciriano group as a Postdoctoral Fellow in Hinxton, Cambridgeshire! Here, you'll dive deep into the fascinating world of cancer genomics, focusing on the intricacies of genome instability and how it impacts tumorigenesis and drug response. Your primary responsibility will be to develop groundbreaking computational methods for analyzing high-throughput sequencing data sets from human tumors and cell-free DNA samples across various cancer types, including both adult and pediatric tumors. This position presents a fantastic opportunity for those passionate about early cancer detection and long-read sequencing data analysis. If you hold a PhD in life sciences and possess strong programming skills, preferably in Python and R, this could be the perfect fit for you. You’ll collaborate closely with clinical and wet-lab teams, bringing your innovative ideas to life while also having the freedom to explore your own hypotheses. You'll be part of a supportive and inclusive community dedicated to pushing the boundaries of genomic medicine. With substantial developmental support and a commitment to professional growth, this role provides the chance to make a real impact in the field of cancer research. If you're ready to lead your own project and work alongside national and international collaborators, we encourage you to apply today and embark on a fulfilling journey in cancer genomics with us!

Frequently Asked Questions (FAQs) for Postdoctoral Fellow Role at EMBL
What are the responsibilities of a Postdoctoral Fellow at the Cortes-Ciriano group?

As a Postdoctoral Fellow in the Cortes-Ciriano group, your key responsibilities will include developing scalable computational solutions for high-throughput sequencing data analysis, leading projects that analyze long-read whole-genome sequencing data sets from human tumors, and collaborating with clinical scientists to enable early cancer detection strategies. You'll need to exhibit strong analytical skills while working both independently and in a team-oriented environment.

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What qualifications do I need to become a Postdoctoral Fellow in Hinxton?

To qualify for the Postdoctoral Fellow position at the Cortes-Ciriano group, you should possess a PhD in the life sciences, ideally in subjects like computational biology or genomics. Strong programming skills in Python and R, significant experience in computational genomics (preferably cancer genomics), and the ability to communicate effectively in English are also critical for success in this role.

Join Rise to see the full answer
Is experience in long-read sequencing data analysis required for the Postdoctoral Fellow position?

While experience in long-read sequencing data analysis is preferred, it is not a strict requirement for the Postdoctoral Fellow role at the Cortes-Ciriano group. What is essential, however, is a strong background in computational genomics, which will enable you to effectively contribute to the group's innovative cancer detection research.

Join Rise to see the full answer
What is the working environment like for a Postdoctoral Fellow at EMBL-EBI?

At EMBL-EBI, the work environment for a Postdoctoral Fellow is collaborative and inclusive, emphasizing innovation and creativity. Located on the beautiful Wellcome Genome Campus, you'll enjoy flexible hybrid working options and a relaxed atmosphere, all while engaging in cutting-edge research. Our team fosters a culture where your contributions are valued and supported, providing a nurturing space for professional growth.

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How does the EMBL Fellows’ Career Service support Postdoctoral Fellows?

The EMBL Fellows’ Career Service offers invaluable support for Postdoctoral Fellows at the Cortes-Ciriano group, aiding in career planning whether you're interested in academia, industry, or entrepreneurial ventures. You’ll have access to resources, guidance from dedicated Career Advisors, and a variety of activities aimed at fostering your professional development throughout your fellowship.

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Common Interview Questions for Postdoctoral Fellow
Can you describe your experience with high-throughput sequencing data analysis?

When answering this question, focus on your specific experiences with high-throughput sequencing technologies, the datasets you have worked with, and the tools used for your analyses. Highlight any projects where your analysis led to significant findings and how it contributed to the team’s goals.

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What programming languages are you proficient in, and how have you used them in your past work?

Discuss your proficiency in programming languages like Python and R, providing examples of how you've applied these languages in computational genomics, data analysis, or algorithm development. Mention any projects where your coding skills improved the analysis process or added value to your research outcomes.

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How do you approach developing new algorithms for genomic data analysis?

Articulate your methodology for creating algorithms, starting from identifying gaps or needs in current methodologies, brainstorming potential solutions, and validating your algorithms with robust testing. Share any specific algorithms you've developed, including their impact on your projects.

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Can you provide an example of a successful collaborative project you were involved in?

When sharing an example of a collaborative project, focus on your role and the contributions you made within the team. Discuss how you navigated challenges, communicated with collaborators, and the outcomes of that project. Highlight the importance of teamwork in achieving shared research goals.

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What challenges do you anticipate facing when analyzing long-read sequencing data?

Discuss potential challenges such as data complexity, bioinformatics bottlenecks, or integration with existing datasets. Emphasize your problem-solving skills and how you plan to tackle these challenges through effective planning, collaboration, and leveraging computational tools.

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What experience do you have with Unix-based environments and high-performance computing?

Share specifics about your familiarity with Unix systems and high-performance computing resources, including any relevant projects where you utilized these environments to optimize data analysis processes. Stress the importance of these tools in handling large genomic datasets effectively.

Join Rise to see the full answer
Describe your experience with data visualization techniques.

Highlight any data visualization tools you've used, such as R's ggplot2 or Python's Matplotlib, and how you've applied them to communicate complex genomic data. Provide specific examples where effective visualizations improved insight and understanding among your team or stakeholders.

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How do you ensure reproducibility in your data analysis workflows?

Explain the techniques and tools you use to enhance reproducibility, including version control software, use of documentation, and scripting of your analysis processes. Emphasize how crucial reproducibility is in scientific research, particularly in computational genomics.

Join Rise to see the full answer
Why are you interested in joining the Cortes-Ciriano group as a Postdoctoral Fellow?

Articulate your passion for the group's research focus and how it aligns with your career goals. Mention specific projects or aspects of the group's work that excite you and detail how your skills and background position you as a strong asset to their ongoing research efforts.

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What are your long-term career aspirations within the field of genomic medicine?

Discuss your future goals, whether they include pursuing an academic path, moving into industry roles, or making contributions to independent research. Highlight how the Postdoctoral Fellow position at the Cortes-Ciriano group fits into your career plans and contributes to your aspirations.

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DATE POSTED
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