Senior Antibody MCM Development Lead - job 1 of 2

Join us and make YOUR mark on the World!

Are you interested in joining some of the brightest talent in the world to strengthen the United States’ security? Come join Lawrence Livermore National Laboratory (LLNL) where our employees apply their expertise to create solutions for BIG ideas that make our world a better place.

We are dedicated to fostering a culture that values individuals, talents, partnerships, ideas, experiences, and different perspectives, recognizing their importance to the continued success of the Laboratory’s mission.

Pay Range

$202,500 - $256,824 Annually

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting; pay will not be below any applicable local minimum wage.  An employee’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, seniority, geographic location, performance, and business or organizational needs.

We have an opening for a senior scientist to lead antibody medical countermeasure development, joining ongoing innovative projects developing biologics against infectious diseases.  You will be responsible for overseeing the development of antibody drug products from initial concept through to initial testing and handoff to partners for drug trails. You will lead activities conducted by cross-functional, interdisciplinary teams, including exploring technical feasibility, developing strategy, performing laboratory validation, and anticipating follow on regulatory requirements toward IND filing. Preferred candidates will have extensive experience with infectious disease research as well as experience managing translational research processes aimed at preparing biologics for pre-clinical trials. This position is in the Biosciences and Biotechnology Division.

You will

• Lead the development of antibody drug products. This includes coordinating and leading subject matter experts to assess technical feasibility and strategic benefits of potential new antibody products, working with team leads responsible for computational antibody design as well as leads responsible for antibody production and characterization.
• Collaborate with cross-functional, interdisciplinary, teams, including R&D efforts on new assay development and new laboratory technologies.
• Collaborate with external partners that provide reagents, assays, and/or protein production capabilities.
• Develop product development strategies, including working with project managers to define and track highly complex multi-year project plans, timelines, and budgets.
• Prepare scientific reports summarizing results from highly complex research activities performed onsite and with partner organizations.
• Work with antibody production team to oversee recombinant mammalian and bacterial protein expression and purification.
• Interface with computational teams performing computational design.
• Lead multi-location research teams
• Anticipate project shortcomings in advance and direct resources to develop effective solutions to improve efficiency in key areas relevant antibody design and discovery.
• Share research results in peer-reviewed journals
• Develop and maintain relationships with external partners and collaborators.
• Stay up-to-date with industry trends and advancements in antibody technology.
• Initiate and/or lead collaborative projects requiring involvement of a broader scientific community.
• Perform other duties as assigned.

• Must be eligible to access the Laboratory in compliance with Section 3112 of the National Defense Authorization Act (NDAA).  See Additional Information section below for details.
• Ph.D. in Molecular Biology, Cell Biology, or related field the equivalent combination of education and related experience.
• Highly advanced experience in antibody product development for infectious disease countermeasures, including experience in antibody generation and development, assay design, and antibody purification
• Substantial knowledge of cell biology, molecular biology, and biotechnology
• Expert with laboratory management, including molecular biology and cell biology
• Substantial experience with recombinant mammalian and bacterial protein expression and purification
• Expert leadership, communication, and project management skills.
• Significant experience developing and managing workflows for high throughput antibody production and screening platforms.
• Expert written, verbal communication and interpersonal skills necessary to deliver presentations, prepare written reports and to interact with a diverse set of scientists, engineers, and other technical and administrative staff.

Qualifications We Desire

• Significant experience with regulatory submissions and compliance
• Proven track record of leading cross-functional teams and developing successful product development strategies
• Expertise in library display technologies for high throughput screening, e.g., mammalian cell-based expression/display, yeast display, and/or other platforms.
• Extensive experience with additional protein purification and characterization techniques.

All your information will be kept confidential according to EEO guidelines.

Position Information

This is a Career Indefinite position, open to Lab employees and external candidates.

Why Lawrence Livermore National Laboratory?

• Included in 2025 Best Places to Work by Glassdoor!
• Flexible Benefits Package
• 401(k)
• Relocation Assistance
• Education Reimbursement Program
• Flexible schedules (*depending on project needs)
• Our values - visit https://www.llnl.gov/inclusion/our-values

Security Clearance

None required.  However, if your assignment is longer than 179 days cumulatively within a calendar year, you must go through the Personal Identity Verification process.  This process includes completing an online background investigation form and receiving approval of the background check.  (This process does not apply to foreign nationals.) 

National Defense Authorization Act (NDAA)

The 2025 National Defense Authorization Act (NDAA), Section 3112, generally prohibits citizens of China, Russia, Iran and North Korea without dual US citizenship or legal permanent residence from accessing specific non-public areas of national security or nuclear weapons facilities.  The restrictions of NDAA Section 3112 apply to this position.  To be qualified for this position, Candidates must be eligible to access the Laboratory in compliance with Section 3112.

Pre-Employment Drug Test

External applicant(s) selected for this position must pass a post-offer, pre-employment drug test. This includes testing for use of marijuana as Federal Law applies to us as a Federal Contractor.

Wireless and Medical Devices

Per the Department of Energy (DOE), Lawrence Livermore National Laboratory must meet certain restrictions with the use and/or possession of mobile devices in Limited Areas. Depending on your job duties, you may be required to work in a Limited Area where you are not permitted to have a personal and/or laboratory mobile device in your possession.  This includes, but not limited to cell phones, tablets, fitness devices, wireless headphones, and other Bluetooth/wireless enabled devices.  

If you use a medical device, which pairs with a mobile device, you must still follow the rules concerning the mobile device in individual sections within Limited Areas.  Sensitive Compartmented Information Facilities require separate approval. Hearing aids without wireless capabilities or wireless that has been disabled are allowed in Limited Areas, Secure Space and Transit/Buffer Space within buildings.

How to identify fake job advertisements

Please be aware of recruitment scams where people or entities are misusing the name of Lawrence Livermore National Laboratory (LLNL) to post fake job advertisements. LLNL never extends an offer without a personal interview and will never charge a fee for joining our company. All current job openings are displayed on the Career Page under “Find Your Job” of our website. If you have encountered a job posting or have been approached with a job offer that you suspect may be fraudulent, we strongly recommend you do not respond.

To learn more about recruitment scams: https://www.llnl.gov/sites/www/files/2023-05/LLNL-Job-Fraud-Statement-Updated-4.26.23.pdf

Equal Employment Opportunity

We are an equal opportunity employer that is committed to providing all with a work environment free of discrimination and harassment. All qualified applicants will receive consideration for employment without regard to race, color, religion, marital status, national origin, ancestry, sex, sexual orientation, gender identity, disability, medical condition, pregnancy, protected veteran status, age, citizenship, or any other characteristic protected by applicable laws.

Reasonable Accommodation

Our goal is to create an accessible and inclusive experience for all candidates applying and interviewing at the Laboratory.  If you need a reasonable accommodation during the application or the recruiting process, please use our online form to submit a request. 

California Privacy Notice

The California Consumer Privacy Act (CCPA) grants privacy rights to all California residents. The law also entitles job applicants, employees, and non-employee workers to be notified of what personal information LLNL collects and for what purpose. The Employee Privacy Notice can be accessed here.