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Senior Scientist I Biotherapeutics Discovery

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on XFacebookInstagramYouTubeLinkedIn and Tik Tok.

Job Description

Discovery Biotherapeutics and Genetic Medicine (BGM) at Abbvie is seeking a highly motivated research scientist to join the Cell and Functional Biology group at the Cambridge Research Center (CRC). The CRC site based in Cambridge, MA offers a unique setting where BGM, Immunology, Neuroscience, and Genomic Research Center co-exist.  In this role, you will be responsible for the conceptualization and execution of cell- and protein- based functional characterization assays for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC. The ideal candidate should have strong experience with cell-based assays, cell culture and antibody screening and significant experience in flow cytometry, fluorescence-based assays and imaging. Familiarity with high-throughput screening and multi-specifics is highly valued. The applicant should be able to analyze, document, and report data. You should possess excellent communication skills and be comfortable working in cross-functional teams.

 

Job Responsibilities:

  • Lead the development and implementation of cell-based fluorescent assays to enable function-first antibody screening across multiple therapeutic areas and drug discovery stages.
  • Design, optimize, and validate assay protocols, ensuring robustness and reproducibility across projects.
  • Analyze and interpret complex data sets, providing insights and recommendations for next steps in research projects.
  • Stay abreast of technological advancements in cell-based assays, fluorescence applications, and imaging techniques to support the expansion of function-first assay design.
  • Develop close cross-functional relationships with therapeutic area scientists to drive synthesis of innovative ideas and solutions to achieve organizational goals.
  • Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment

Qualifications

Qualifications:

  • BS with 10+ years of experience or MS with 8+ years of experience or PhD with no experience in Biology, Molecular and Cellular Biology, Biomedical Engineering, Immunology or other related field.
  • Proficient in conceptualization and implementation of in vitro cell-based assays.
  • Experience with fluorescent based assay development with expertise in cell-culture, flow cytometry, ELISA/microplate cytometry and imaging platforms.
  • Proficiency in data analysis and statistical software.
  • Ability to work independently as well as part of a collaborative team environment.
  • Strong attention to quality and details when exercising organizational, documentation and communication skills.

Desirable:

  • Experience with high-throughput screening, programming and multi-specific antibodies.
  • Experience with external collaborations and partnerships.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​​

​​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​​

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​​

  • This job is eligible to participate in our short-term incentive programs. ​​

​​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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Average salary estimate

$135000 / YEARLY (est.)
min
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$120000K
$150000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

What You Should Know About Senior Scientist I Biotherapeutics Discovery, AbbVie

AbbVie is on the lookout for a Senior Scientist I in Biotherapeutics Discovery to join our innovative team at the Cambridge Research Center. This is a fantastic opportunity for someone passionate about making a significant impact in the fields of immunology, oncology, neuroscience, and more. In this role, you'll be integral to the Cell and Functional Biology group, where you'll take the lead on developing and implementing exciting cell-based functional characterization assays that are pivotal for antibody identification and optimization. The best part? You'll have the chance to collaborate across different therapeutic areas, driving real innovation. If you're someone with a rich background in cell-based assays, strong experience in flow cytometry, and an enthusiasm for high-throughput screening, you’ll fit right in. You'll be tasked with not only analyzing complex data sets but also staying on top of technological advancements to keep our research cutting-edge. This is a fast-paced multi-disciplinary environment, and while everyone here brings their unique skills to the table, excellent communication and teamwork are highly valued. Join us at AbbVie, and you'll be part of a mission focused on delivering novel medicines that genuinely alter lives for the better.

Frequently Asked Questions (FAQs) for Senior Scientist I Biotherapeutics Discovery Role at AbbVie
What are the responsibilities of a Senior Scientist I in Biotherapeutics Discovery at AbbVie?

As a Senior Scientist I in Biotherapeutics Discovery at AbbVie, you'll lead the development of cell-based assays, implement assay protocols, analyze complex data sets, and collaborate with various therapeutic teams to drive innovative solutions in drug discovery.

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What qualifications are required for the Senior Scientist I position at AbbVie?

To qualify for the Senior Scientist I role at AbbVie, candidates should ideally hold a BS with 10+ years of experience or an MS with 8+ years in a relevant field, alongside proficiency in cell culture, flow cytometry, and experience with antibody screening and analysis.

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What skills are essential for a Senior Scientist I in the Biotherapeutics Discovery field at AbbVie?

A Senior Scientist I in Biotherapeutics Discovery at AbbVie must possess strong analytical skills, proficiency in assay development, and excellent communication abilities. Experience in high-throughput screening and detailed documentation skills are also essential.

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How does AbbVie support the growth and development of its Senior Scientists?

AbbVie fosters a collaborative environment focused on innovation, providing resources for professional development, and opportunities for external collaborations, allowing Senior Scientists to contribute to diverse projects and stay informed on industry advancements.

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What type of environment can a Senior Scientist I in Biotherapeutics Discovery at AbbVie expect?

At AbbVie, a Senior Scientist I in Biotherapeutics Discovery can expect a fast-paced, multi-disciplinary environment that values teamwork, promotes scientific excellence, and encourages sharing of innovative ideas among peers.

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Common Interview Questions for Senior Scientist I Biotherapeutics Discovery
Can you describe your experience with cell-based assays for the Senior Scientist I position at AbbVie?

Discuss your specific experiences in designing and implementing cell-based assays, including methodologies used, challenges faced, and successful outcomes. Highlight your ability to adapt techniques based on project needs.

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How do you approach analyzing complex data sets in your research?

Explain your systematic approach to data analysis, including software tools used, statistical methods, and how you translate data into actionable insights for research projects.

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What are some challenges you’ve faced in antibody screening and how did you overcome them?

Focus on a specific challenge you've encountered in antibody screening, detailing the problem, your creative solution, and the results achieved. Emphasize your perseverance and innovative thinking.

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Can you share your experience with flow cytometry and how it relates to the role?

Provide a brief overview of your hands-on experience with flow cytometry, including specific assays or experiments, and how this expertise will contribute to your success in the Senior Scientist I role.

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How do you keep up with advancements in cell-based assays and technologies?

Discuss any professional development courses, conferences, or journals you engage with, emphasizing your commitment to continuous learning and how this benefits your research practices.

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What role does teamwork play in your approach to scientific research?

Illustrate your communication style, how you interact with cross-functional teams, and specific examples of successful collaborations that led to project advancements.

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How do you ensure the robustness and reproducibility of your assay protocols?

Share methods you use to validate assay protocols, such as control experiments, repeat trials, and documentation practices that ensure reliability in your findings.

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What motivates you to pursue a career in biotherapeutics discovery?

Articulate your passion for the field, discussing specific experiences or events that inspired you to contribute to developing innovative therapeutics that can enhance patient lives.

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How do you handle tight deadlines and multiple projects in a fast-paced environment?

Discuss your time-management strategies, prioritization techniques, and how you remain flexible and focused under pressure while ensuring quality work.

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Why do you want to work at AbbVie specifically?

Share your admiration for AbbVie's mission and values, and discuss how you believe your skills and experiences align with the company's goals in drug discovery and patient care.

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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: i...

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DATE POSTED
March 18, 2025

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