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Senior Software Engineer, Infrastructure Engineering - job 1 of 2

10x Genomics is looking for a Senior Software Engineer to build their growing cloud infrastructure and HPC platform. This role requires expertise in Linux, cloud, and distributed computing in a collaborative environment.

Skills

  • Software engineering experience in Python or Golang.
  • Linux systems engineering and operational experience.
  • Experience with AWS services and infrastructure.
  • Infrastructure as Code knowledge (ex. Terraform, Ansible).
  • CI/CD tools experience.

Responsibilities

  • Design, build, deploy, and maintain resilient and scalable services and High Performance Computing (HPC) systems in the cloud.
  • Scale systems and improve operational efficiency through extensive automation.
  • Collaborate with the software engineering team on continuous delivery and deployment.
  • Monitor infrastructure and applications for uptime and resource utilization.
  • Identify performance bottlenecks and troubleshoot system issues.
  • Maintain detailed documentation of system build and operational procedures.
  • Participate in on-call rotations.

Education

  • Bachelor’s degree in Computer Science or a related field, or equivalent work experience.

Benefits

  • Base pay range of $183,000—$247,600 USD.
  • Eligibility for equity grants.
  • Comprehensive health and retirement benefits.
  • Annual bonus program or sales incentive program.
To read the complete job description, please click on the ‘Apply’ button
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Average salary estimate

$215300 / YEARLY (est.)
min
max
$183000K
$247600K

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What You Should Know About Senior Software Engineer, Infrastructure Engineering, 10x Genomics

Are you ready to take your career to the next level? 10x Genomics is on the hunt for a Senior Software Engineer for our Infrastructure Engineering team based in Pleasanton, California! In this role, you'll be at the forefront of building our dynamic cloud infrastructure and cutting-edge High Performance Computing (HPC) platform. If you’re passionate about Linux, cloud computing, and want to contribute to a team of talented experts across various disciplines, this is the perfect opportunity for you. Imagine designing and maintaining resilient, scalable services while collaborating with a diverse group of professionals dedicated to scientific innovation. Your experience with automation, monitoring infrastructure, and implementing best practices will shine here. You’ll be involved in everything from troubleshooting performance issues to scaling systems effectively. Not to mention, you'll get to enhance your skills in tools such as AWS, Terraform, and Kubernetes. Whether you are diving into codebases or documenting procedures, your contributions will be vital to our mission of advancing biology. If you are a self-starter, eager to learn new technologies, we want to hear from you! Join us at 10x Genomics, where your expertise can make a real difference.

Frequently Asked Questions (FAQs) for Senior Software Engineer, Infrastructure Engineering Role at 10x Genomics
What are the key responsibilities of a Senior Software Engineer at 10x Genomics?

As a Senior Software Engineer at 10x Genomics, your key responsibilities will include designing, building, and maintaining resilient cloud services and HPC systems. You'll collaborate with the engineering team on continuous delivery, monitor application uptime, troubleshoot performance bottlenecks, and enhance operational efficiency through automation.

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What qualifications are required for the Senior Software Engineer position at 10x Genomics?

To qualify for the Senior Software Engineer role at 10x Genomics, candidates should have a Bachelor’s degree in Computer Science or a related field, along with 5 years of software engineering experience in Python or Golang and 3 years of Linux systems engineering experience. Familiarity with AWS services, Infrastructure as Code, and CI/CD tools is crucial.

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What preferred skills can enhance a Senior Software Engineer’s application at 10x Genomics?

Preferred skills for a Senior Software Engineer at 10x Genomics include proficiency in shell scripting and languages like Python or Go, experience with Docker and Kubernetes, and knowledge of Linux kernel tuning. Strong problem-solving abilities and excellent communication skills are also important.

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What is the work environment like for a Senior Software Engineer at 10x Genomics?

The work environment at 10x Genomics is collaborative and dynamic, encouraging team members to pursue their passions and innovative ideas. As a Senior Software Engineer, you'll work alongside a diverse group of professionals in a hybrid setting, where creativity and contribution are highly valued.

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What is the salary range for the Senior Software Engineer position at 10x Genomics?

The salary range for the Senior Software Engineer position at 10x Genomics is between $183,000 and $247,600. Actual compensation will depend on various individual factors, including skills and experience, along with additional benefits like equity grants and health programs.

Join Rise to see the full answer
Common Interview Questions for Senior Software Engineer, Infrastructure Engineering
Can you explain your experience with cloud infrastructure?

When answering this question, emphasize your previous projects involving AWS or similar cloud platforms. Discuss specific tools you have used, challenges you faced, and how you improved the architecture or performance of cloud solutions.

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What is your approach to troubleshooting in a Linux environment?

Highlight your systematic approach to troubleshooting, including how you utilize logs, performance metrics, and system commands to diagnose issues. Share specific examples of problems you've solved and the outcomes to showcase your effectiveness.

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How do you ensure your applications are reliable and scalable?

Discuss your experience with service design, load testing, and the implementation of monitoring tools. Explain how you focus on automation, continuous integration, and deployment strategies to maintain high availability and performance.

Join Rise to see the full answer
Describe a project where you utilized Infrastructure as Code.

Select a project that showcases your proficiency with tools like Terraform or Ansible. Discuss the challenges faced, solutions implemented, and how infrastructure automation improved efficiency and reduced errors in the deployment process.

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What is your experience with containerization and orchestration?

Talk about your familiarity with Docker for building containers and Kubernetes for orchestration. Share specific scenarios where you set up, configured, or troubleshot applications in a containerized environment.

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How do you handle performance optimization in systems?

Focus on methodologies you apply for performance tuning, such as load testing, analyzing bottlenecks, and applying best practices. Include examples where your optimizations led to significant improvements in performance metrics.

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How do you maintain documentation for your systems and procedures?

Explain your commitment to maintaining comprehensive documentation throughout the development lifecycle. Discuss the tools you use and give examples of how documentation supports operational efficiency and knowledge sharing.

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What continuous integration and deployment tools have you used?

Mention specific CI/CD tools you've utilized, like Jenkins or GitLab CI, and how you’ve optimized deployment pipelines. Discuss any challenges encountered and how you ensured quality and speed in the release process.

Join Rise to see the full answer
Can you describe your experience with high-performance computing systems?

Share specific details about HPC systems you've worked on, the applications used, and any optimizations you implemented. Highlight your understanding of parallel processing and computational workload management.

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How do you keep current with emerging technologies in software engineering?

Discuss your strategies for staying updated, such as attending conferences, participating in forums, or self-study. Mention specific new technologies you’ve explored recently and how they can be incorporated into your work at 10x Genomics.

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At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advanc...

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FUNDING
SENIORITY LEVEL REQUIREMENT
TEAM SIZE
SALARY RANGE
$183,000/yr - $247,600/yr
EMPLOYMENT TYPE
Full-time, hybrid
DATE POSTED
March 11, 2025

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