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Principal Software Engineer, AI

Natera™ is a global leader in cell-free DNA testing, focusing on oncology and women's health. We are seeking a Principal AI Engineer to lead AI initiatives enhancing lab operations.

Skills

  • Expertise in Python, Java, SQL
  • Deep understanding of AI/ML frameworks
  • Strong problem-solving skills

Responsibilities

  • Develop a strategic roadmap for AI-driven lab operations optimization.
  • Architect Generative AI solutions leveraging cloud AI frameworks.
  • Design full-stack AI-driven applications that integrate workflow automation.

Education

  • Bachelors in Computer Science or related field
  • Masters or PhD is a plus

Benefits

  • Comprehensive medical, dental, vision plans
  • 401k benefits
  • Free genetic testing for employees and families
To read the complete job description, please click on the ‘Apply’ button
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What You Should Know About Principal Software Engineer, AI, Natera

As a Principal Software Engineer specializing in AI at Natera in San Carlos, California, you'll be at the forefront of revolutionizing lab operations through cutting-edge technology. Your primary responsibility will be to lead various AI initiatives that enhance efficiency and usher in intelligent decision-making processes in high-throughput environments. You'll work on developing AI-driven task automation, sophisticated workflow guidance, and insightful analytics, ultimately transforming how laboratories operate. In this pivotal role, you'll define AI strategies, spearhead advancements in Generative AI, deep learning, and machine learning, while collaborating with amazing cross-functional teams. You’ll have your hands on creating solutions that include architecting innovative Generative AI models using tools like AWS Bedrock and SageMaker, fine-tuning large language models, and ensuring AI applications deliver seamless user experiences. You won’t just be a part of the evolution—you'll be leading it! With a strong emphasis on cloud solutions and advanced AI engineering, your projects will not only optimize operations but truly empower teams. Join a passionate group of professionals at Natera, committed to pushing the envelope in the field of genetic testing and diagnostics. If you're ready to take on a challenge and make a significant impact in prenatal health and oncology through technology, this could be your perfect role!

Frequently Asked Questions (FAQs) for Principal Software Engineer, AI Role at Natera
What are the primary responsibilities of a Principal Software Engineer, AI at Natera?

The Principal Software Engineer, AI at Natera is tasked with developing and executing a strategic roadmap aimed at optimizing lab operations through AI-driven solutions. This includes leading efforts in Generative AI, deep learning, and machine learning, with a focus on task automation, workflow guidance, and enhancing user experience through intelligent applications.

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What qualifications are required to become a Principal Software Engineer, AI at Natera?

To be considered for the Principal Software Engineer, AI position at Natera, candidates should have at least 12 years of experience in software development, with strong expertise in programming languages like Python and Java. Familiarity with AI/ML frameworks is essential, along with hands-on experience deploying models in cloud environments such as AWS. Candidates should also demonstrate a strategic mindset for AI adoption.

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What technologies will I work with as a Principal Software Engineer, AI at Natera?

As a Principal Software Engineer, AI at Natera, you'll work with advanced technologies including AWS tools like SageMaker and Bedrock, as well as machine learning frameworks such as PyTorch, TensorFlow, and Scikit-learn. You'll focus on innovative solutions involving Generative AI and large language models.

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How does Natera support AI-driven solutions in lab operations?

Natera drives AI-driven solutions in lab operations by developing real-time applications that provide predictive insights, automating workflows, and creating user-friendly interfaces. By leveraging cutting-edge AI technologies, Natera ensures efficiency and accuracy in lab processes, ultimately benefiting patient health.

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What type of work culture can I expect as a Principal Software Engineer, AI at Natera?

Natera fosters a collaborative work culture that emphasizes diversity and inclusion. As a Principal Software Engineer, AI, you'll be surrounded by a dedicated team of professionals who are passionate about making a difference in genetic testing and diagnostics. The work environment encourages innovation, growth, and continuous learning.

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Common Interview Questions for Principal Software Engineer, AI
Can you explain your experience with Generative AI and how it applies to lab automation?

In this response, discuss specific projects where you've implemented Generative AI. Highlight your familiarity with AI models, detailing how these solutions enhanced lab workflows through automation, increased efficiency, or improved data management, reinforcing the overarching goal of lab operations optimization.

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What strategies do you employ for AI model optimization in high-throughput environments?

Elaborate on your experience regarding AI/ML models, focusing on best practices like regular model fine-tuning and deployment processes. Additionally, discuss your familiarity with MLOps practices that ensure continuous improvement and reliability in high-throughput environments.

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Describe a challenge you faced while developing an AI application and how you overcame it.

Share a specific instance detailing the challenge you encountered, such as balancing model accuracy with computational efficiency. Explain the steps you took to analyze, iterate, and implement solutions, showcasing your problem-solving skills and dedication to achieving results.

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How do you stay updated on the latest AI technologies and trends?

Discuss your methods for keeping abreast of industry advancements, such as attending conferences, participating in online forums, or pursuing certifications. Mention specific resources you trust to enhance your knowledge base, which emphasizes your commitment to professional development.

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What are your thoughts on responsible AI practices?

This is your opportunity to express your understanding of ethical AI development. Discuss the importance of addressing biases, ensuring compliance with regulatory frameworks, and advocating for transparent AI systems that uphold user privacy and promote fair outcomes.

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How do you approach cross-functional collaboration in your projects?

Discuss your belief in the importance of teamwork and communication amongst diverse roles. Share specific experiences where collaboration led to innovative solutions or streamlining project delivery, emphasizing your ability to lead and unite a team with shared goals.

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Can you provide an example of an AI-driven application you've developed?

Detail a specific project from conception to implementation, focusing on the objectives, technologies used, and the impact it had. Emphasize how it contributed to efficiency or decision-making in a lab context, illustrating your hands-on experience in AI application development.

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What tools do you find most effective for AI model deployment?

Share your favorite tools, such as AWS services or specific ML frameworks you've worked with, and describe their strengths in facilitating successful model deployment. Explain how these tools enhance collaboration and scalability, indicating your extensive experience and proficiency.

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How do you ensure scalability and security in your AI solutions?

Discuss specific strategies you implement to balance scalability with robust security protocols, particularly in cloud environments. Emphasize best practices in securing data and models in production and providing safe access for both users and stakeholders.

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What led you to pursue a career in AI and software engineering?

This question gives you a chance to share your passion for technology and innovation. Talk about the influences in your life that drew you towards AI, any key experiences that solidified your interest, and how you envision your future contributions to the field.

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DATE POSTED
March 29, 2025

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