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Senior Director, AI/ML Engineering

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

 

Join us to deploy and implement cutting-edge AI/ML models addressing complex challenges in life science R&D areas including target choice, patient identification, molecule design and clinical trial effectiveness. Collaborate with data scientists and leverage cloud infrastructure to build scalable training pipelines, ensuring rapid iterations and operational excellence. Develop robust backend systems and evaluation frameworks while engaging in technology assessments and co-development with strategic partners to support GenAI products across R&D functions.

 

 

Job Description  

      Deploy and implement advanced AI/ML models to tackle complex problems in target choice, patient identification, molecule design/chemistry, manufacturing and controls (CMC), and clinical trial effectiveness.

      Design and implement distributed training pipelines for LLMs using tools such as DeepSpeed, ensuring scalability and efficiency.

      Collaborate with Data Scientists in LLM customization: pre-training, fine-tuning, reinforcement learning with human feedback (RLHF), and applying parameter efficient fine-tuning (PEFT) techniques.

      Define and implement repeatable AI/ML pipelines to ensure rapid iterations of data science experiments while leveraging the cloud infrastructure to implement industry best practice in MLOps.

      Model operationalization and monitoring on Azure and GCP infrastructures with close collaboration with the DevSecOps team.

      Build scalable, reusable backend systems including the state-of-the-art agentic frameworks to support GenAI products across R&D functions. Develop robust logging, telemetry, and evaluation harnesses to ensure reliable model performance.

      Technology assessment of external product solutions and co-development with strategic partners

      Create and maintain pipelines for producing training/testing/validation data sets

      Build and maintain model evaluation framework

      Build strong relationships with key stakeholders across GSK, effectively communicating the value proposition of AI/ML and fostering a culture of data-driven decision-making.

      Develop and manage budgets, resource allocation, and timelines for responsible AI/ML projects

      Recruit and develop AI/ML talents, set direction/objectives, and manage overall on-time high-quality delivery.

      Continuously benchmark GSK AI/ML capabilities, stay ahead of industry trend, identify opportunities for optimization and innovation to drive great impact and ROI.

 

Basic Qualifications

      BS degree in computer science, engineering, or equivalent quantitative science fields (e.g., bioinformatics, applied math) 

      10+ years of engineering experience in high-velocity, high-growth companies.

      Strong track record of working with LLM technologies, including GenAI embedding techniques, modern model architecture, retrieval-augmented generation (RAG), fine tuning/pre-training AI models, and evaluation benchmarks

      Proficiency in Python, TensorFlow/PyTorch, and scalable ML architectures.

      Proficiency in Agentic framework, i.e., AutoGen and LangGraph

      Proficiency in Azure and GCP cloud services

      Expertise in full stack software development, and familiarity with software engineering principles around testing, code reviews and deployment.

      Strong analytical and problem-solving skills, with a passion for shaping AI-driven workflow.

      Strong written and verbal communication skills

      5+ years of people leader experience to scale one or more technical capability areas

 

Preferred Qualifications 

      MA degree in computer science or engineering

      10-15 years of combined full stack, data engineering, Azure/GCP cloud services, and AI engineering experience

      Experience with graph databases in the context of GraphRAG

      Experience with data lake-house architecture, data catalog, master data management applications 

      Experience in establishing AI/ML and agent best practices, standards, and ethics

      Experience in AI/ML applications in life science domain areas: pre-clinical research, clinical trial design and operation, precision medicine, regulatory science, and CMC.

      Experience in reducing the cost of running a service / capability while maintaining or improving performance efficiencies

Please visit  GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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What You Should Know About Senior Director, AI/ML Engineering, GSK

Join GSK as a Senior Director of AI/ML Engineering in Philadelphia, Pennsylvania, and become a pivotal part of our mission to unite science, technology, and talent to advance healthcare solutions. At GSK, we are not just a biopharma company; we are a dedicated team striving to transform lives and get ahead of diseases through cutting-edge innovations. In this dynamic role, you will lead the deployment and implementation of advanced AI and ML models that solve complex challenges in life science R&D. You'll partner with talented data scientists to customize language models and build scalable training pipelines, ensuring rapid iterations in our work. You will have the opportunity to shape the future of patient identification, molecule design, and clinical trial effectiveness, directly impacting healthcare outcomes. Collaboration will be key, as you develop strong relationships across GSK, fostering a culture of data-driven decision-making. Your expertise in Python, TensorFlow, and cloud services like Azure and GCP will help design robust backend systems that support our GenAI products. This is more than just a job; it’s a chance to contribute to a purpose-driven organization where your ideas can have a monumental impact. If you’re passionate about shaping AI-driven workflows and are excited about leading a stellar team to new heights, we’d love for you to join us in this important journey together.

Frequently Asked Questions (FAQs) for Senior Director, AI/ML Engineering Role at GSK
What responsibilities does the Senior Director of AI/ML Engineering at GSK entail?

As the Senior Director of AI/ML Engineering at GSK, you will oversee the implementation and deployment of advanced AI and ML models across various domains. Key responsibilities include leading AI initiatives in clinical trial design, patient identification, and molecule design. You will manage teams, ensuring the development of scalable training pipelines and fostering collaboration with data scientists. Engaging with stakeholders and conducting technology assessments will also be part of your role.

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What qualifications are required for the Senior Director AI/ML Engineering position at GSK?

To qualify for the Senior Director of AI/ML Engineering role at GSK, candidates need a BS degree in computer science, engineering, or a related quantitative field. A decade of engineering experience, particularly with LLM technologies and cloud services such as Azure and GCP, is essential. Leadership experience and familiarity with software engineering principles will substantially strengthen your candidacy.

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How does GSK support the growth of employees in the Senior Director AI/ML Engineering role?

At GSK, we prioritize employee growth and well-being. As a Senior Director in AI/ML Engineering, you'll lead high-performing teams, set clear objectives, and foster an environment of learning and development. GSK offers comprehensive benefits and opportunities for professional advancement, ensuring you can thrive both personally and within your career.

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What technologies will the Senior Director of AI/ML Engineering be working with at GSK?

The Senior Director of AI/ML Engineering at GSK will work with a variety of advanced technologies, including Python, TensorFlow, and PyTorch. You will also engage in the customization of LLMs using cutting-edge techniques like reinforcement learning and parameter-efficient fine-tuning. In addition, proficiency with Azure and GCP cloud infrastructures will be crucial for model operationalization and monitoring.

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What impact can the Senior Director of AI/ML Engineering have on GSK's mission?

In the role of Senior Director of AI/ML Engineering at GSK, your contributions will directly impact patient health outcomes by enhancing the precision and efficacy of clinical trials and innovations. By deploying advanced AI solutions and leading transformative projects, you'll help drive forward GSK’s mission to effectively address diseases and improve patient care globally.

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Common Interview Questions for Senior Director, AI/ML Engineering
Can you describe your experience with AI and ML technologies relevant to the Senior Director role?

In your response, focus on specific AI/ML projects you've led, detailing the technologies and methodologies used, as well as your role in addressing key challenges. Highlight your expertise with LLM technologies and mention specific successes in previous positions to demonstrate your qualifications.

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How do you approach collaboration with data scientists and technical teams?

Emphasize your collaborative skills by sharing specific examples of projects where you successfully worked with cross-functional teams. Discuss the importance of fostering open communication, delegating tasks effectively, and ensuring that everyone is aligned with project goals to maintain continuity and efficiency.

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What strategies do you implement to ensure the successful operationalization of AI models?

Discuss best practices in MLOps, touching on the importance of monitoring, testing, and iteration post-deployment. Share examples of how you've structured AI pipelines and utilized cloud services to enhance scalability and performance in your previous roles.

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How do you stay informed about emerging trends in AI/ML and apply them at GSK?

Articulate your process for staying current with industry trends, such as attending conferences, following relevant publications, or engaging in professional networks. Explain how you've integrated new knowledge into workplace strategies to improve AI capabilities in past projects.

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Can you explain a challenging AI project you've managed and its outcomes?

Narrate a particular project challenge you faced, the specific steps you took to resolve it, and the resulting impact on the organization. Highlight your problem-solving skills and reinforce the significance of teamwork in overcoming obstacles.

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What key performance indicators (KPIs) do you consider essential for AI projects?

Discuss your perspective on KPIs such as model accuracy, operational efficiency, and return on investment. Mention how you utilize these KPIs to benchmark performance and guide decision-making to optimize the performance of AI initiatives.

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How have you successfully recruited and developed talent in the AI/ML field?

Provide insights into your approach to talent acquisition and development, emphasizing mentorship, clear goal-setting, and creating opportunities for growth. Share examples of how you’ve built high-performing teams and improved their capabilities over time.

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What are your thoughts on ethical considerations in AI/ML implementation?

It's crucial to discuss the importance of ethical AI practices, sharing your views on fairness, transparency, and accountability. Offer examples of how you've approached ethical challenges in past projects to highlight your commitment to responsible AI development.

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How do you manage timelines and resources for multiple AI projects concurrently?

Talk about your project management strategies, including prioritization, the use of project management tools, and how you allocate resources effectively. Highlight your experience in keeping projects on track and meeting deadlines.

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What role do you think AI will play in the future of the biopharma industry?

Reflect on the transformative potential of AI in biopharma, touching on aspects like drug discovery, patient care, and operational efficiencies. Support your view with market examples and trends to demonstrate a forward-thinking mindset.

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We know that healthy communities depend on healthy people, and healthy communities are the backbone of strong, sustainable societies. As a business, we have responsibilities to society, and society has expectations of us. Our goal is to meet those...

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BENEFITS & PERKS
Dental Insurance
Disability Insurance
Vision Insurance
Flexible Spending Account (FSA)
Health Savings Account (HSA)
Performance Bonus
Family Medical Leave
Paid Holidays
FUNDING
DEPARTMENTS
SENIORITY LEVEL REQUIREMENT
TEAM SIZE
EMPLOYMENT TYPE
Full-time, on-site
DATE POSTED
April 3, 2025

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