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Executive Director, Business Transformation and Agility

If you have the passion and the drive to accelerate growth and make people’s lives better – then AstraZeneca is the place for you.  In Operations we have a big ambition – to deliver more medicines to patients, quicker and more affordably. Backed by the investment, leadership and a clear plan to get there, we bring personal dedication and out of the box thinking. 

AstraZeneca turns molecules to medicines, bringing our Research & Development pipeline to life through a rigorous process of development, manufacturing, testing and delivery.  Operations is accelerating, fast. We are on track for Our Bold Ambition 2030, delivering 15+ new medicines driving us forward across different modalities including biologics, cell therapy, ADCs and small molecules. 

Position Summary

The Executive Director, Business Transformation and Agility is responsible for the management of overall Business Strategy and CMC Portfolio on a regional and/or global level and input in the global strategy for Project, Change, Business Improvement and Strategy Management of Cell Therapy Development and Operations. Recognized as a thought leader and expert within own area of specialization.

The ideal candidate for this role will be curious, creative, analytical with a natural leadership drive to bring solutions beyond immediate challenges; challenge the status quo and will have outstanding communication and influencing skills. This leader will share frequent interactions with senior leaders across Global Operations, as well as close collaboration with leaders of R&D of multiple Therapy areas. Success in this role will result in improved business decision-making, accelerated innovation, and enhanced productivity. A passion for transformation, combined with relationship-building, leadership, and communication skills will be key to success.

The position will report into the Vice President, Global Cell Therapy Development and Operations.  The position can be based in Gaithersburg, MD or Santa Monica, CA.


Responsibilities

  • Accountable for defining and executing CTDO business transformation strategies which will enable superior quality, effectiveness and efficiency of the business whilst ensuring delivery of top priority objectives to achieve the 2030 bold ambition
  • Establish and drive CTDO transformation roadmap structure and strategy that enable #1 place in Cell Therapy Operations by 2030 Enable successful organizational integration of respective process development/clinical and commercial manufacturing teams across the CTDO sites, ensuring consistent and sustainable organization to deliver on 2030 bold ambition
  • Identify high level opportunities for process improvement and drive implementation of the key process improvement and lean initiatives that will ensure successful launch and management of multiple products and pipeline.
  • Drive synergies, simplification and productivity initiatives and achieve cost efficiencies for CTDO organization. Lead cross functional teams to identify top operational challenges and supporting transformation programs that will strengthen supply model for autologous and allogenic modalities.
  • Actively collaborate with key networks across AZ and externally to gain awareness of current industry trends to contribute and influence new evolving technologies and practices. Share strategic outcomes of key strategy implementation and Business transformation projects with senior leadership teams, outlining benefits from a cost, speed and quality perspective and demonstrating the return on investment (ROI)

Ensuring Great Place to Work

  • Establish, manage and implement global operational strategies for CTDO sites.
  • Oversee global transformation projects, developing sustainable plans for process, projects, and organizational talent to ensure seamless delivery of new products and the pipeline.
  • Build a trusting relationship with senior leaders and other key stakeholders across the enterprise to advise and influence operational transformational changes supporting 2030 bold ambition
  • Articulate and engage on proactive communication with key stakeholders on strategy implementation

Minimum Requirements

  • Bachelor’s degree in appropriate discipline
  • Minimum 4 years in operational strategy

Preferred Requirements

  • Superior project management skills with demonstrated experience successfully managing a cross-functional or cross-departmental team on a sophisticated project
  • Comfort with ambiguity and the ability to logically structure issues and determine recommended resolutions
  • Demonstrated ability to set and manage priorities, resources, performance targets and project initiatives in a global environment
  • Operational expertise in proactive risk management and contingency planning
  • Conceptual, analytical, with demonstrated strategic thinking capability
  • Ability to work well under pressure and effectively and professionally navigate tough situations
  • Ability to challenge the status quo, take ownership and holds self and others accountable
  • Ability to influence strategically and persuade tactfully, to obtain desired outcomes while maintaining effective, positive, organizational relationships
  • Passion for Patients and Customers, representing the needs of multiple customers in decision making

Desirable Education, Qualifications, Skills and Experience

  • Masters or PhD or other advanced degree in appropriate discipline with MBA
  • CMC and Operations project management experience, preferably in launch and post-launch
  • PMP certification
  • Experience with driving lean/six sigma/process improvement
  • Vast experience in building Agile delivery and execution capabilities across global teams
  • Strong experience in relationship management and influencing skills
  • Effective problem and conflict resolution skills and proven team focus
  • Excellent knowledge of AstraZeneca policies, procedures and guidelines
  • Experience in working with senior leaders

When we put unexpected teams in the same room, we fuel bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the Gaithersburg, MD or Santa Monica, CA office. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base salary for this position ranges from $220,000 to $330,000. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related experience. If hired, employee will be in an “at-will position” and we reserve the right to modify base salary (and any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

02-Apr-2025

Closing Date

20-Apr-2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
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Average salary estimate

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$330000K

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What You Should Know About Executive Director, Business Transformation and Agility, AstraZeneca

If you're ready to take on a significant leadership role, look no further than the Executive Director, Business Transformation and Agility position at AstraZeneca in Gaithersburg, MD. This is an exciting opportunity for a driven individual passionate about pushing the boundaries of growth and healthcare innovation. At AstraZeneca, we firmly believe in delivering transformative medicines to patients more efficiently and affordably, and in this position, you’ll be at the forefront of that mission. You will be responsible for managing our business strategy and CMC portfolio on a global scale while collaborating closely with leaders in R&D and Operations. We are on an ambitious path towards our Bold Ambition 2030, which aims to introduce over 15 new medicines. We're looking for a thought leader who can effectively challenge the status quo, drive process improvement, and integrate our clinical and commercial manufacturing teams. With your exceptional communication and leadership abilities, you'll guide cross-functional teams to tackle operational challenges and implement transformative initiatives that enhance productivity and decision making. If you possess a blend of creativity, analytical skills, and a passion for change, AstraZeneca is the perfect fit for you. Join us as we continue to revolutionize the healthcare landscape, ensuring that we not only meet but exceed our goals for the next decade and beyond.

Frequently Asked Questions (FAQs) for Executive Director, Business Transformation and Agility Role at AstraZeneca
What are the primary responsibilities of the Executive Director, Business Transformation and Agility at AstraZeneca?

The Executive Director, Business Transformation and Agility at AstraZeneca is responsible for steering the overall business strategy and ensuring the efficiency of our CMC portfolio. This role entails defining and executing transformative strategies, enabling successful integration of manufacturing teams, and driving process improvements that align with our 2030 objectives.

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What qualifications are necessary for the Executive Director position at AstraZeneca?

Candidates for the Executive Director, Business Transformation and Agility at AstraZeneca should possess at least a bachelor's degree in a relevant discipline and a minimum of four years in operational strategy. Preferred qualifications include a master's degree or MBA, alongside project management expertise, preferably in CMC and operations.

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How does the Executive Director at AstraZeneca foster collaboration across global teams?

In the role of Executive Director, fostering collaboration is key, and at AstraZeneca, this is achieved through regular communication with senior leaders and actively engaging with cross-functional teams. This leader will oversee global transformation projects and ensure that organizational strategies align seamlessly across all sites.

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What skills are essential for success in the Executive Director role at AstraZeneca?

Essential skills for the Executive Director, Business Transformation and Agility at AstraZeneca include superior project management capabilities, effective risk management, strategic thinking, and strong relationship management. The ability to influence stakeholders and challenge the status quo are equally important.

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What is AstraZeneca’s vision for the 2030 Bold Ambition related to this role?

AstraZeneca’s 2030 Bold Ambition aims to deliver at least 15 innovative medicines to patients. The Executive Director will play a critical role in achieving this vision by driving operational improvements, enhancing decision-making processes, and ensuring the successful launch of multiple products and therapies.

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Common Interview Questions for Executive Director, Business Transformation and Agility
Can you describe your experience with business transformation initiatives?

When answering this question, highlight specific examples of transformation projects you have led. Discuss the strategies you employed, the challenges faced, and the outcomes achieved. Emphasize your role in leading cross-functional teams and how your efforts contributed to organizational growth.

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How do you approach risk management in a global operational context?

Your response should outline your understanding of proactive risk management. Share instances where you identified potential risks early, implemented measures to mitigate them, and ensured contingency planning was in place. Discuss your ability to adapt to global dynamics.

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What strategies do you employ to influence senior leadership on operational changes?

Discuss your approach to building relationships with senior leaders. Highlight your skills in persuasive communication, presenting data-driven insights, and articulating the benefits of proposed changes. The key is to demonstrate how you align operational goals with organizational priorities.

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How do you ensure successful integration of cross-departmental teams?

Share your methods for fostering collaboration between teams, such as establishing clear communication channels, defining shared goals, and leveraging team strengths. Provide examples of how you've previously managed integration during transformative initiatives.

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What experience do you have with project management in complex environments?

Describe your project management experience by discussing specific projects you have successfully navigated, particularly in operations or manufacturing. Mention the frameworks you used, the teams you managed, and how you ensured projects met their deliverables within time and budget constraints.

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What makes you passionate about driving business transformation?

This is your opportunity to convey your enthusiasm for transformation. Share personal anecdotes that illustrate your commitment to improving processes, enhancing efficiencies, and ultimately impacting patient care. Let your genuine passion shine through.

Join Rise to see the full answer
Can you give an example of how you've challenged the status quo?

Provide a clear scenario where you identified an entrenched practice that needed change. Detail your thought process, the steps you took to advocate for change, and the eventual results. Use this question to showcase your innovative mindset.

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How do you stay updated with industry trends that affect business operations?

Discuss the various tools and resources you utilize to keep informed about industry trends, such as attending conferences, reading relevant publications, or networking with industry professionals. Describe how you apply this knowledge to inform your strategic decisions.

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What tools or methodologies do you utilize for process improvement?

Mention specific process improvement methodologies like Lean or Six Sigma that you've implemented in past roles. Describe how you assess processes and engage your team in identifying areas for improvement, ensuring buy-in for changes.

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How do you measure success in your role as a leader?

Talk about the metrics or KPIs you prioritize to evaluate the success of initiatives and teams under your leadership. Being data-driven is crucial, so provide examples of how these measures directly influence decision-making and strategy execution.

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AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We’re consta...

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DATE POSTED
April 4, 2025

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